quinolin-8-ol (CAS 148-24-3) — Safety Data Sheet

quinolin-8-ol carries a harmonised entry in CLP Annex VI under index 613-[CAS?]. This page covers the safety data sheet issued for it — a document, not a supply of the material.

quinolin-8-ol (CAS 148-24-3) at a glance

• Substance – quinolin-8-ol
• CAS number – 148-24-3
• EC number – 205-711-1
• CLP Annex VI index number – 613-[CAS?]
• Also known as – 8-hydroxyquinoline
• Hazard statements – H360D (may damage the unborn child); H301 (toxic if swallowed); H318 (causes serious eye damage); H317 (may cause an allergic skin reaction); H400 (very toxic to aquatic life); H410 (very toxic to aquatic life with long lasting effects)
• Hazard classes – Repr. 1B, Acute Tox. 3, Eye Dam. 1, Skin Sens. 1, Aquatic Acute 1, Aquatic Chronic 1
• Label pictograms – GHS05, GHS06, GHS08, GHS09
• Signal word – Danger
• Concentration limits / M-factor / ATE – M = 1;M = 1
• Entry current as of – ATP10
• CMR classification – yes, classified as carcinogenic, mutagenic or toxic for reproduction
• Documentation issued – safety data sheet in REACH Annex II structure; working draft or signed card
• What is supplied – a document. MolGod.org does not sell, supply or ship chemical substances.

Storage and handling in the document

Section 7 of the documentation for quinolin-8-ol details handling and storage procedures, including incompatible materials, conditions to be avoided, and any segregation requirements resulting from its classification. Laboratories reviewing this section need explicit instructions rather than general warnings; for example, a statement like ‘store in a cool dry place’ is insufficient because it leaves the responsibility of specifying precise storage conditions to the personnel.

First-aid content and why it is read first

When an exposure to quinolin-8-ol happens, nobody reads sixteen sections. They read section 4, and they read it in the language of the person holding the sheet. Both facts should shape how that section is written and translated.

How is quinolin-8-ol classified for road, sea and air transport?

Section 14 for CAS 148-24-3 includes the UN number, correct shipping name, class, packing group, and environmental hazard where applicable. If the substance is not hazardous for transportation, Section 14 explicitly states this rather than being left empty; an empty Section 14 is interpreted as an omission rather than a lack of hazard.

What is the EC number for quinolin-8-ol?

Alongside CAS 148-24-3, this substance carries EC number 205-711-1 and Annex VI index 613-[CAS?]. European documentation is built around the EC number as often as around the CAS: registration dossiers, the candidate list and customs systems key on it. A safety data sheet quoting only one of the two forces every downstream reader to look up the other.

What Annex VI notes and concentration limits apply to quinolin-8-ol?

The register also records M = 1;M = 1 for this entry. Specific concentration limits, M-factors and acute toxicity estimates override the generic cut-off values, so a mixture calculation that ignores them will classify the mixture wrongly in both directions.

What is the CLP classification of quinolin-8-ol?

The harmonised classification for CAS 148-24-3 carries 6 hazard statements: H360D, H301, H318, H317, H400, H410. In plain terms this means may damage the unborn child; toxic if swallowed; causes serious eye damage; may cause an allergic skin reaction. A harmonised entry is binding across the Union — an importer may not soften it, and a self-classification that diverges from it will not survive an enforcement check.

Accidental release and containment

A spill involving substance with CAS number 148-24-3 must be managed according to Section 6, which should clearly specify the required containment materials and personal protective equipment necessary for personnel approaching the spill site. An operational sheet outlining the cleanup process without detailing the appropriate attire for workers is considered incomplete.

Which GHS pictograms apply to quinolin-8-ol?

The label for quinolin-8-ol carries GHS05 (corrosion), GHS06 (skull and crossbones), GHS08 (health hazard), GHS09 (environment), with the signal word Danger. These are not chosen by the supplier: CLP Annex VI states them for CAS 148-24-3, and the precedence rules in Annex I decide which pictogram is dropped when two would say the same thing. A label showing a different set from the register is wrong even if every hazard statement on it is correct.

Sensitisation and declaration thresholds

Sensitisation (H317) carries consequences beyond the label: a threshold for declaring the substance in mixtures far below the general cut-off, and — where the entry is on the candidate list — an obligation to inform recipients. Importers frequently discover this at the point where a customer asks for a declaration they had not prepared.

Who is responsible for REACH compliance for quinolin-8-ol?

The responsibility for documentation accompanying quinolin-8-ol rests with the entity introducing it into the Union market, rather than with any external supplier. Importers share the same obligations as manufacturers, including designating a identifiable EU contact in section 1. A non-EU supplier may appoint a sole representative, but this appointment must be established prior to the movement of goods, not in response to subsequent inquiries.

Can I import quinolin-8-ol into the EU?

The introduction of quinolin-8-ol into the Union necessitates the preparation of documentation prior to logistical arrangements. The documentation file must be available at the time of import, not merely upon request; for this purpose, heterocyclic compounds is assessed within the context of active-ingredient and intermediate imports. Index 613-[CAS?] establishes the classification that Section 2 must reflect accordingly.

Is quinolin-8-ol classified as a CMR substance?

CAS 148-24-3 is classified as a CMR substance (H360D). That status changes the obligations attached to every shipment: workplace exposure documentation, restrictions on supply to the general public, and substitution pressure from downstream users who must justify continued use. A safety data sheet for a CMR substance is read more closely than any other, because the classification itself invites scrutiny.

Why a correct sheet stops being correct

Classification under CLP moves with each Adaptation to Technical Progress. A sheet for CAS 148-24-3 written before the amendment that touched its entry keeps stating a classification the register no longer holds. Nothing in the document announces this — it reads exactly as it did on the day it was issued, which is precisely why revision dates are checked before content.

What must the label for quinolin-8-ol contain?

The supply label for quinolin-8-ol is generated from the same classification that drives the safety data sheet: pictograms selected by precedence, one signal word derived from the highest hazard class present, and the hazard statements H360D, H301, H318… reproduced in full. Where the container is too small to carry the complete set at a legible size, there are lawful ways to handle it and unlawful ones that look identical to a non-specialist.

Where is regulatory status recorded for quinolin-8-ol?

The regulatory status of quinolin-8-ol evolves separately from its hazard classification. A substance may maintain consistent hazard characteristics over extended periods while gaining additional obligations under Section 15, leading to this section becoming outdated more rapidly than Section 2.

Identifiers that must agree

CAS 148-24-3 and index number 613-[CAS?] are not interchangeable and not decorative. The index number ties the entry to the harmonised classification; the CAS number ties it to the chemical literature. A file carrying one without the other forces every reader to reconstruct the link, and reconstruction is where errors enter.

What concentration limits apply to quinolin-8-ol?

M-factor on record: 1. The M-factor multiplies the contribution of this substance in the aquatic hazard calculation for a mixture, which is where it is most often overlooked.

Purity, certificates and what the sheet does not say

Purity grade is a certificate question, not a safety data sheet question. The sheet for quinolin-8-ol describes the substance; a certificate of analysis describes one batch of it, with the measured result against the specification and the analytical method named per parameter. Laboratories asking for ‘the COA’ usually need both documents.

Questions about documentation for quinolin-8-ol

Can I check whether my existing sheet is still valid?

Yes. A section-by-section reading against Annex II and the current harmonised entry establishes that in one pass, and a sheet that passes is reported as passing.

Do I need a safety data sheet to import quinolin-8-ol into the EU?

Yes. A sheet compiled to Annex II of REACH must exist before the first consignment moves, and it must be held by the entity placing the substance on the Union market.

What is the CAS number of quinolin-8-ol?

CAS 148-24-3. In CLP Annex VI the same substance carries index number 613-[CAS?], and both identifiers should appear in the documentation.

Is quinolin-8-ol a CMR substance?

Yes. The harmonised classification places it among substances classified as carcinogenic, mutagenic or toxic for reproduction, which changes workplace documentation and supply restrictions.

MolGod.org issues documentation and does not sell, supply or ship chemical substances. CAS 148-24-3 identifies the subject of this document.