vanillin-CAS-121-33-5-—-Safety-Data-Sheet CAS_NUMBER 121-33-5 (de_DE)

vanillin (CAS 121-33-5) — Safety Data Sheet

Safety data sheet documentation for vanillin (CAS 121-33-5), compiled to REACH Annex II. Vanillin has no harmonised entry in CLP Annex VI; the sheet states its classification basis (aggregated ECHA C&L notifications). Two options: a working draft sent by e-mail immediately, or a signed card issued within 72 hours of complete input. The item supplied is a document — MolGod.org does not sell, supply or ship chemical substances.

Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.

REACH 2020/878
v4 · 10.09.2026
Download Safety Data Sheet (PDF)CAS 121-33-5 · PDF · 152 KBWorking draft — not yet reviewed and approved.

Section 9 — physicochemical properties: 10 of 22 established.

We show what is established and name what is not. Classification and identity are complete on every card; section 9 is where public data is thin.

This page sells the documentation for this substance, not the substance. Choose the level you need.

  1. €0Audit the sheet you already haveSend us your existing sheet for this substance and we tell you what is wrong with it. One per company. If it turns out to be sound, you buy nothing.Start the free audit →
  2. €49.99Working draftThe complete sixteen-section document, referenced, downloadable immediately after checkout. The right choice while the paperwork is still moving.
  3. €249.99Signed cardThe same document reviewed and signed, issued within 72 hours of complete input — for the moment somebody official asks who stands behind it.

Documentation available for this substance: safety data sheet · CLP label · certificate of analysis on request · specification. Languages: the official language of your destination market, produced per card.

Grade, purity, physical form, packaging, minimum order and lead time are not shown, because MolGod does not supply the material — those are facts about a seller, and there is no seller on this page. They appear on storefronts we build for suppliers, where somebody can answer for them.

See a finished document firstFull price list →

What you receive — and what this is not

What you receive

  • A digital PDF safety data sheet in the sixteen-section structure of REACH Annex II (Regulation 1907/2006).
  • Substance identification, hazard classification, physicochemical, toxicological and ecological information, and regulatory references.
  • Classification read against the harmonised entry in CLP Annex VI where one exists for the substance.
  • A version number, a compilation date, and the source behind each value that carries one.
  • Delivery by e-mail. Nothing is shipped.

What this is not

  • Not a chemical substance, not a sample, not any physical goods.
  • Not a certification. No official certification scheme for safety data sheets exists in the European Union.
  • Not legal approval, and not a guarantee of compliance in any jurisdiction.
  • Not a substitute for your own regulatory assessment, nor for the safety data sheet supplied by the manufacturer or importer of the substance you actually hold.
  • Not adapted to a specific workplace, process or national annex unless you provide that information.

Where the available evidence does not support a value, the sheet states that the value is not established rather than estimating one. A field with no recorded source is marked as such.

What is in the buyer pack

Everything your compliance officer will ask for, in one file.

  • The product page as PDF — the record as published, so what you forward matches what you read.
  • The safety data sheet at your entitlement level — sixteen sections in the order set by REACH Annex II, for this substance, in the language you select.
  • The CLP label artwork — generated from the same classification as the sheet, so the two cannot disagree.
  • The specification, and the certificate of analysis where batch data exists.
  • sources.txt — every citation with the date it was read.
  • An explicit list of what we could not establish — fields marked unavailable rather than filled with an estimate. This is the honest part of the document and we do not hide it in a footnote.

Your European buyer is going to forward this to somebody who was not on the call. The pack exists so that what they forward is complete, self-explanatory and traceable — rather than four attachments and a sentence beginning “I think this is everything”.

SKU: SDS-121-33-5 Category:

These switch the language of this page. Single substances. Mixtures on enquiry. One document, one language — additional languages are priced separately. Every version, including the Chinese one, is written to EU law — (EC) No 1907/2006 (REACH) Annex II and (EU) 2020/878 — and translated from it. The Chinese version is a reference translation, not a legally valid document for the Chinese market: an SDS for China must be compiled separately to GB/T 16483 and GB/T 17519.

🧬 3D-Molekül-Visualisierer
Molekül wird geladen...
3D-Modell Vanillin, CAS 121-33-5, Summenformel C8H8O3, molare Masse 152.15 g/mol

Daten transkribiert aus regulatorischen Registern und Fachliteratur, unter Angabe von Quelle und Ausgabe. Sie ersetzen nicht das Sicherheitsdatenblatt des Lieferanten. Felder ohne hinterlegte Quelle sind als solche gekennzeichnet.

📊 Physikochemische Daten — CAS 121-33-5
📊 Physikochemische Eigenschaften

Kurzübersicht

Formel: C8H8O3
MW: 152.15 g/mol
CAS: 121-33-5
🔬 Erweiterte Eigenschaften

Chemische Kennungen

SMILES: COC1=C(C=CC(=C1)C=O)O

Zuletzt aktualisiert: 2026-10-07

Chemische Übersicht: Vanillin
SummenformelC8H8O3[1]
Molekulargewicht152.15 g/mol[1]
Schmelzpunkt82 °C[1][2]
Siedepunkt285 °C[1][3]
Dichte1.06 g/cm³[1]
LogP (Lipophilie)1.2[1]
IUPAC-Name4-hydroxy-3-methoxybenzaldehyde[1]
SMILESCOC1=C(C=CC(=C1)C=O)O[1]
InChIKeyMWOOGOJBHIARFG-UHFFFAOYSA-N[1]

Synonyme: vanillin · 4-Hydroxy-3-methoxybenzaldehyde · 121-33-5 · Vanillic aldehyde · Vanillaldehyde

Datenquellen: PubChem (NLM/NIH)
Zuletzt aktualisiert: 2026-09-02

📚 Wissenschaftliche Referenzen (Chicago Author-Date) (3 Quellen)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. ↗ dotyczy: Summenformel · Molekulargewicht · Schmelzpunkt · Siedepunkt · Dichte · LogP (Lipophilie) · IUPAC-Name · SMILES · InChIKey
  2. NIST. Chemistry WebBook, SRD 69. National Institute of Standards and Technology. ↗ dotyczy: Schmelzpunkt
  3. NLM. Hazardous Substances Data Bank (HSDB). National Library of Medicine. ↗ dotyczy: Siedepunkt

WISSENSCHAFTLICHE FORSCHUNG

[1]PubMed2025
Divanillin Cross-Linked Recyclable Cellulose Networks.
Zhang M, Subramaniyan S, Hakkarainen M. (2025). "Divanillin Cross-Linked Recyclable Cellulose Networks.". Macromolecular rapid communications. https://doi.org/10.1002/marc.202401094
Zur vollständigen Studie ↗
[2]PubMed2025
Milnacipran and Vanillin Alleviate Fibromyalgia-Associated Depression in Reserpine-Induced Rat Model: Role of Wnt/β-Catenin Signaling.
Kamaly NA, Kamel AS, Sadik NA et al.. (2025). "Milnacipran and Vanillin Alleviate Fibromyalgia-Associated Depression in Reserpine-Induced Rat Model: Role of Wnt/β-Catenin Signaling.". Molecular neurob
Zur vollständigen Studie ↗
[3]PubMed2025
Vanillin alleviates oxidative stress-mediated neuronal pyroptosis induced in rats by isoproterenol via SIRT1/NOX4/ROS/TXNIP/NLRP3 signaling pathway.
Abdelghafour AM, Mahrous M, Zaher ME. (2025). "Vanillin alleviates oxidative stress-mediated neuronal pyroptosis induced in rats by isoproterenol via SIRT1/NOX4/ROS/TXNIP/NLRP3 signaling pathway.". Fo
Zur vollständigen Studie ↗
[4]PubMed2024
Genetic Engineering Approaches for the Microbial Production of Vanillin.
Santos LDF, Lautru S, Pernodet JL. (2024). "Genetic Engineering Approaches for the Microbial Production of Vanillin.". Biomolecules. https://doi.org/10.3390/biom14111413
Zur vollständigen Studie ↗
[5]PubMed2024
Paulina S. Gennermann 2023: Eine Geschichte mit Geschmack. Die Natur synthetischer Aromastoffe im 20. Jahrhundert am Beispiel Vanillin und Lisa…
Stoff H. (2024). "Paulina S. Gennermann 2023: Eine Geschichte mit Geschmack. Die Natur synthetischer Aromastoffe im 20. Jahrhundert am Beispiel Vanillin und Lisa Haushofer 2022: Wonder Foods: The Scie
Zur vollständigen Studie ↗
[6]PubMed2023
Strategies for improving the production of bio-based vanillin.
Liu Y, Sun L, Huo YX et al.. (2023). "Strategies for improving the production of bio-based vanillin.". Microbial cell factories. https://doi.org/10.1186/s12934-023-02144-9
Zur vollständigen Studie ↗
[7]PubMed2022
Biosynthesis of vanillin by different microorganisms: a review.
Ma Q, Liu L, Zhao S et al.. (2022). "Biosynthesis of vanillin by different microorganisms: a review.". World journal of microbiology & biotechnology. https://doi.org/10.1007/s11274-022-03228-1
Zur vollständigen Studie ↗
[8]PubMed2021
Therapeutic role of vanillin receptors in cancer.
Rakoczy K, Szlasa W, Saczko J et al.. (2021). "Therapeutic role of vanillin receptors in cancer.". Advances in clinical and experimental medicine : official organ Wroclaw Medical University. https://d
Zur vollständigen Studie ↗
📚 Wissenschaftliche Referenzen (Chicago Author-Date) 9 refs · 1 baz

MOLECULE Bibliografie pro CAS (live aus 13+ Datenbanken)

Quellen: db:pubmed (9)

  1. db:pubmed Zhang M, Subramaniyan S, Hakkarainen M. (2025). "Divanillin Cross-Linked Recyclable Cellulose Networks.". Macromolecular rapid communications. https://doi.org/10.1002/marc.202401094 →
  2. db:pubmed Kamaly NA, Kamel AS, Sadik NA et al.. (2025). "Milnacipran and Vanillin Alleviate Fibromyalgia-Associated Depression in Reserpine-Induced Rat Model: Role of Wnt/β-Catenin Signaling.". Molecular neurobiology. https://doi.org/10.1007/s12035-025-04723-w →
  3. db:pubmed Abdelghafour AM, Mahrous M, Zaher ME. (2025). "Vanillin alleviates oxidative stress-mediated neuronal pyroptosis induced in rats by isoproterenol via SIRT1/NOX4/ROS/TXNIP/NLRP3 signaling pathway.". Food & function. https://doi.org/10.1039/d4fo06458e →
  4. db:pubmed Santos LDF, Lautru S, Pernodet JL. (2024). "Genetic Engineering Approaches for the Microbial Production of Vanillin.". Biomolecules. https://doi.org/10.3390/biom14111413 →
  5. db:pubmed Stoff H. (2024). "Paulina S. Gennermann 2023: Eine Geschichte mit Geschmack. Die Natur synthetischer Aromastoffe im 20. Jahrhundert am Beispiel Vanillin und Lisa Haushofer 2022: Wonder Foods: The Science and Commerce of Nutrition.". NTM. https://doi.org/10.1007/s00048-024-00384-3 →
  6. db:pubmed Liu Y, Sun L, Huo YX et al.. (2023). "Strategies for improving the production of bio-based vanillin.". Microbial cell factories. https://doi.org/10.1186/s12934-023-02144-9 →
  7. db:pubmed Ma Q, Liu L, Zhao S et al.. (2022). "Biosynthesis of vanillin by different microorganisms: a review.". World journal of microbiology & biotechnology. https://doi.org/10.1007/s11274-022-03228-1 →
  8. db:pubmed Rakoczy K, Szlasa W, Saczko J et al.. (2021). "Therapeutic role of vanillin receptors in cancer.". Advances in clinical and experimental medicine : official organ Wroclaw Medical University. https://doi.org/10.17219/acem/139398 →
  9. db:pubmed Kojder PL, Erickson CL. (2021). "Airborne Allergic Contact Dermatitis to Vanillin.". Dermatitis : contact, atopic, occupational, drug. https://doi.org/10.1097/DER.0000000000000677 →
Regulatorischer Status der Substanz
Diese Substanz unterliegt regulatorischen Anforderungen: Bewirtschaftung gefährlicher Abfälle (BDO — nationale Vorschrift, Polen). Details im Abschnitt "Regulatorischer Status (REACH/ECHA/CLP)" und im SDS. Regulatorische Information — schränkt den Kauf in diesem Shop nicht ein.
🧮 Stöchiometrie-Rechner
🧪 Chemische Daten
CAS-Nummer
121-33-5
Summenformel
C8H8O3
Molmasse
152.15 g/mol
IUPAC-Name (EN)
4-hydroxy-3-methoxybenzaldehyde
SMILES
COC1=C(C=CC(=C1)C=O)O
InChIKey
MWOOGOJBHIARFG-UHFFFAOYSA-N
📡 Data sources

The data in this widget comes from the following verified scientific sources:

  • PubChem — National Center for Biotechnology Information (NCBI/NIH), USA
  • ChEMBL — European Bioinformatics Institute (EMBL-EBI), UK
  • NIST WebBook — National Institute of Standards and Technology, USA

Data is cached locally for speed — the widget also works offline.

⚗️ Physicochemical properties
Temp. topnienia
82
Density
1.056

Source: PubChem, NIST WebBook. Last updated: 2026-10-07

🔍 Externe Identifikatoren
14 von 16 ID-Systemen88%
DatenbankIdentifikatorAktionen
CAS Registry Number121-33-5Öffnen →
PubChem CID1183[1]Öffnen →
InChIKeyMWOOGOJBHIARFG-UHFFFAOYSA-N[1]Öffnen →
InChIInChI=1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,…[1]
SMILESCOC1=C(C=CC(=C1)C=O)O[1]
EC Number204-465-2[2]Öffnen →
ChEMBLCHEMBL13883[3]Öffnen →
KEGG CompoundD00091Öffnen →
HMDBHMDB0012308Öffnen →
ChemSpider13860434[4]Öffnen →
MeSH UID (NLM)C100058Öffnen →
UNII (FDA)CHI530446XÖffnen →
NSC Number (NCI)15351Öffnen →
WikiData QIDQ33495Öffnen →

Quellen: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Wissenschaftliche Referenzen (Chicago Author-Date) (4 Quellen)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. ↗ dotyczy: PubChem CID · InChIKey · InChI · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. ↗ dotyczy: EC Number
  3. ChEMBL. European Bioinformatics Institute (EMBL-EBI), bioactivity database. ↗ dotyczy: ChEMBL
  4. ChemSpider. Royal Society of Chemistry, chemical structure database. ↗ dotyczy: ChemSpider

Further reading

Publications topically related to this CAS. They are not the source of any value given on this card.

Bibliografie (erweitert) (5)

  1. ★★☆☆☆ CROSSREF 🔓 OFFEN ❓ nicht verifiziert Anonymous. "Vanillin.". https://doi.org/10.31003/fcc_f101484_02_01. Link [abgerufen: 2026-10-07] CC0 (metadata)
  2. ★★☆☆☆ CROSSREF 🔓 OFFEN ❓ nicht verifiziert Anonymous. "Ethyl Vanillin.". https://doi.org/10.31003/fcc_f101260_02_01. Link [abgerufen: 2026-10-07] CC0 (metadata)
  3. ★★☆☆☆ CROSSREF 🔓 OFFEN ❓ nicht verifiziert Anonymous. "Vanillin.". https://doi.org/10.31003/uspnf_m87890_02_01. Link [abgerufen: 2026-10-07] CC0 (metadata)
  4. ★★☆☆☆ CROSSREF 🔓 OFFEN ❓ nicht verifiziert Anonymous. "Ethyl Vanillin.". https://doi.org/10.31003/uspnf_m31950_02_01. Link [abgerufen: 2026-10-07] CC0 (metadata)
  5. ★☆☆☆☆ OPENLIBRARY 🔓 OFFEN William Shober Seese. 1965. "The synthesis of substituted o̲-vanillins." Link [abgerufen: 2026-10-07] CC0 (metadata)
📡 Spektroskopie — CAS 121-33-5
📊 Spektroskopische Spektrendatenbanken — Inline-Daten 9 Quellen

Spektren werden bei Bedarf aus 9 Quellen abgerufen. Jedes Spektrum wird in unserer Datenbank gespeichert — beim nächsten Öffnen erfolgt keine Anfrage an die externe API. Laden Sie JCAMP-DX / CSV / PNG zu jedem Spektrum herunter, ohne zu suchen.

IR IR (Infrared) — NIST WebBook
Public domain (US Federal)
▶ Klicken, um das Spektrum zu laden
🔗 Quelle
— Punkte
📚 NIST Chemistry WebBook, SRD 69
MS (NIST) Mass Spectrum (EI) — NIST WebBook
Public domain (US Federal)
▶ Klicken, um das Spektrum zu laden
🔗 Quelle
— Punkte
📚 NIST Standard Reference Database 1A
UV-Vis UV/Visible Absorption — NIST WebBook
Public domain (US Federal)
▶ Klicken, um das Spektrum zu laden
🔗 Quelle
— Punkte
📚 NIST Chemistry WebBook, SRD 69
¹H NMR NMR (¹H, ¹³C) — NMRShiftDB
nmrshiftdb2 Database License
https://nmrshiftdb.nmr.uni-koeln.de/nmrshiftdbhtml/nmrshiftdb2datalicense.txt
Type of data: Type of data not reported by the source (may be measured or calculated)
Basis: these values match NMRShiftDB record nmrshiftdb2:60005858; type as classified by MolGod from that record.
▶ Klicken, um das Spektrum zu laden
🔗 Quelle
About the downloads (Type of data: Type of data not reported by the source (may be measured or calculated))
JCAMP: the NMRShiftDB file as received (JCAMP-DX 5.01 text). It is a peak list: chemical shift in ppm. MolGod adds header lines stating the type of data; the values are unchanged.
CSV: the same peak list in two columns. The second column repeats the shift value; it is not a signal intensity. Lines starting with # state the type of data.
PNG: a picture of the plot above, with the type of data written on it.
Use: where signals are expected or were reported (chemical shift positions). Not included or guaranteed: intensities, multiplicities, coupling constants, line shapes, and solvent or temperature unless stated. A predicted list is not a measurement and cannot serve as a reference spectrum for identity or purity testing. Downloads become active after Show.
— Punkte
📚 Steinbeck C et al. (2003) J. Chem. Inf. Comput. Sci. 43(1):10–16 DOI: 10.1021/ci025588g
MS (MoNA) MoNA — MassBank of North America
CC-BY 4.0
▶ Klicken, um das Spektrum zu laden
🔗 Quelle
— Punkte
📚 MassBank of North America (UC Davis) DOI: 10.1002/jms.1777
IR/NMR/MS (SDBS) SDBS — Spectral Database for Organic Compounds (Japan AIST)
Free for non-commercial

Referenzquelle — keine öffentliche API. In einer externen Datenbank öffnen:

🔗 IR/NMR/MS (SDBS) →
📚 SDBSWeb: https://sdbs.db.aist.go.jp (AIST, Japan)
JP Monograph Japanese Pharmacopoeia — Monographs
Reference only

Referenzquelle — keine öffentliche API. In einer externen Datenbank öffnen:

🔗 JP Monograph →
📚 Japanese Pharmacopoeia 18th Edition (2021)
WHO INN WHO — International Nonproprietary Names
WHO Model Lists (free)

Referenzquelle — keine öffentliche API. In einer externen Datenbank öffnen:

🔗 WHO INN →
📚 WHO INN Programme
DOAJ DOAJ — Directory of Open Access Journals
OA journal index (mixed)

Referenzquelle — keine öffentliche API. In einer externen Datenbank öffnen:

🔗 DOAJ →
📚 DOAJ — doaj.org

Die Daten werden einmalig abgerufen (JCAMP-DX-Parser) und in der lokalen Datenbank des Plugins gespeichert. Keine doppelten Downloads, keine erneuten Anfragen an NIST bei späteren Aufrufen. Lizenzen werden eingehalten (veröffentlicht wird nur ein Deep-Link plus eigene Visualisierung).

🔬 Interaktive Spektren (live — NIST / MoNA / NMRShiftDB / SDBS) (2)

Daten werden live aus mehreren Quellen abgerufen (Priority-Chain). JCAMP-DX / CSV / PNG stehen unter jedem Spektrum zum Download bereit.

IR — Fourier-Transform-Infrarot

IR — Fourier-Transform-Infrarot wird geladen…

MS — Massenspektrometrie (EI 70eV)

MS — Massenspektrometrie (EI 70eV) wird geladen…

Strukturelle Eigenschaften

Strukturdaten werden geladen...

❓ Häufig gestellte Fragen (3)
What is 121-33-5?
121-33-5 (CAS 121-33-5) is a chemical compound. The chemical data comes from PubChem (National Institutes of Health, USA).
Hilfreich?
What is the CAS number of 121-33-5?
The CAS number for 121-33-5 is 121-33-5. A CAS Registry Number is the standard identifier for a chemical substance in scientific literature and in trade.
Hilfreich?
How should 121-33-5 be stored?
121-33-5 should be stored as its safety data sheet directs \— typically in a dry, cool, well-ventilated place, away from heat and from materials it is incompatible with.
Hilfreich?
➕ Frage vorschlagen
Strukturdateien herunterladen

Molekülstrukturdateien aus der PubChem-Datenbank (NIH). Kompatibel mit Avogadro, PyMOL, Jmol und ChemDraw.

Quelle: PubChem, National Library of Medicine (NIH). CID: 1183

🔄 Umrechner für Konzentrationseinheiten LIVE

Geben Sie die Konzentration Vanillin in einer beliebigen Einheit ein — der Rest wird automatisch berechnet.

MW: 152.15 g/mol · IUPAC Gold Book ↗

⚗️ Umrechnungsformeln + Zitate (pro Formel)
UmrechnungFormelGenauigkeitQuelle
% (w/v) ↔ molarityc (mol/L) = (% × 10) / MW±0.5% rel. when density ≈ 1.0 g/mLIUPAC (2019)
millimolar ↔ molarc (mol/L) = mM × 10⁻³ExactCohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007)
molarity (mol/L)c = n/V = (m/MW)/V±0.1% (depends on MW precision)IUPAC (2019)
parts per million (mg/L) ↔ molarityc (mol/L) = ppm / (1000 × MW); equivalently ppm = mg/L for dilute aqueous±1% (density-independent for dilute solutions)IUPAC (2019)
mg/mL ↔ molarityc (mol/L) = (mg/mL × 1000) / MW / 1000 = mg/mL / MW × 1±0.2%Cohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007)
g/L ↔ molarityc (mol/L) = (g/L) / MW±0.1% (depends on MW precision)Cohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007)
mmol/L ↔ molarityc (mol/L) = mmol/L × 10⁻³ExactCohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007)
Celsius ↔ KelvinT(K) = t(°C) + 273.15±0.01 K (ITS-90 scale)BIPM (Bureau International des Poids et Mesures) (2019)
Celsius ↔ FahrenheitT(°F) = T(°C) × 9/5 + 32±0.1 °FThompson A, Taylor BN (2008)
density-corrected % ↔ molarityc (mol/L) = (%w/w × ρ × 10) / MW, ρ in g/mL±0.1% when ρ known to 3 decimalsCohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007)
📚 Bibliographie (8 autoritative Quellen)
  1. Thompson A, Taylor BN (2008). Guide for the Use of the International System of Units (SI). NIST Special Publication 811 · DOI: 10.6028/NIST.SP.811-2008
    → Primary SI standard for US scientific usage
  2. Cohen ER, Cvitaš T, Frey JG, Holmström B, Kuchitsu K, Marquardt R, Mills I, Pavese F, Quack M, Stohner J, Strauss HL, Takami M, Thor AJ (2007). Quantities, Units and Symbols in Physical Chemistry — The IUPAC Green Book. RSC Publishing, 3rd ed. · DOI: 10.1039/9781847557889 · ISBN: 978-0-85404-433-7
    → Canonical IUPAC guide for chemistry quantities/units
  3. BIPM (Bureau International des Poids et Mesures) (2019). The International System of Units (SI), 9th edition. BIPM · ↗
    → International SI definitions (incl. redefined kilogram 2019)
  4. ISO/IEC (2022). Quantities and units — Part 1: General. International Organization for Standardization — ISO 80000-1:2022 · ↗
    → General rules for physical quantities and units
  5. ISO/IEC (2019). Quantities and units — Part 9: Physical chemistry and molecular physics. International Organization for Standardization — ISO 80000-9:2019 · ↗
    → Concentration / molality / amount-of-substance conventions
  6. Tiesinga E, Mohr PJ, Newell DB, Taylor BN (2021). CODATA recommended values of the fundamental physical constants: 2018. Rev. Mod. Phys. 93(2):025010 · DOI: 10.1103/RevModPhys.93.025010
    → Avogadro, gas constant, molar volume (2019 SI revision)
  7. IUPAC (2019). Compendium of Chemical Terminology — the IUPAC Gold Book (online). IUPAC · DOI: 10.1351/goldbook
    → Definitions of mass fraction, molality, normality, ppm, activity
  8. Mills IM, Cvitaš T, Homann K, Kallay N, Kuchitsu K (1988). Quantities, Units and Symbols in Physical Chemistry. Blackwell Scientific Publications, 1st ed. · ISBN: 0-632-01773-5
    → Historical predecessor of IUPAC Green Book
Ähnliche Molekülstrukturen

Ähnliche Strukturen werden geladen...

🧪 Assistent zur Lösungsvorbereitung WIZARD
① Konzentration auswählen
② Zielvolumen
③ Lösungsmittel

Berechnungen nach: IUPAC Gold Book ↗, Merck ↗

Computerchemie

Berechnungsdaten werden geladen...

🛡️ Sicherheit — CAS 121-33-5
Hinweis zu Datenbeschränkungen. Die Sicherheitsinformationen auf dieser Seite dienen nur zur Information und ersetzen kein vollständiges Sicherheitsdatenblatt (SDS). Konsultieren Sie vor der Verwendung des Produkts das aktuelle Sicherheitsdatenblatt des Herstellers sowie die GHS/CLP-Leitlinien. Die CLP-Einstufung bezieht sich auf die reine Bulk-Substanz, nicht auf handelsübliche Zubereitungen.

GHS/CLP-Einstufung — Verordnung (EG) Nr. 1272/2008 + UN GHS Rev. 9 (2021).

⚠ Achtung (Warning)
GHS07 — Reizend / gesundheitsschädlich
GHS07 Reizend / gesundheitsschädlich
GHS09 — Umweltgefahr
GHS09 Umweltgefahr

🚨 Gefahrenhinweise (H)

  • H319 — Verursacht schwere Augenreizung.
  • H302 — Gesundheitsschädlich bei Verschlucken.
  • H411 — Giftig für Wasserorganismen, mit langfristiger Wirkung.
  • H320 — Verursacht Augenreizung.
  • H402 — Schädlich für Wasserorganismen.
  • H412 — Schädlich für Wasserorganismen, mit langfristiger Wirkung.

🛡 Sicherheitshinweise (P)

  • P261 — Einatmen von Staub/Rauch/Gas/Nebel/Dampf/Aerosol vermeiden.
  • P264 — Nach Gebrauch gründlich waschen.

⚠ Einstufung basierend auf einem Konsens der Quellen (PubChem / Meldungen der Lieferanten) — nicht gegen die harmonisierte Einstufung in Anhang VI (CLP) verifiziert. Der Gefahrenumfang kann breiter sein als die amtliche Einstufung; vor der Verwendung mit dem aktuellen Sicherheitsdatenblatt des Lieferanten verifizieren.

Übersetzungen: CLP-Verordnung (EG) 1272/2008, Anhang III und IV. Daten: PubChem/NLM.

📚 Konsolidierte wissenschaftliche Referenzen — Chicago Author-Date 10 Quellen

Referenzen aus allen Safety-Hub-Registerkarten gesammelt. CAS: 121-33-5 · PubChem ↗

  1. Parlament Europejski i Rada UE. 2008. "Regulation (EC) nr 1272/2008 w sprawie klasyfikacji, oznakowania i pakowania substancji (CLP)." Dz.Urz. UE L 353. [↗] GHS, Vorschriften
  2. United Nations Economic Commission for Europe (UNECE). 2021. "Globally Harmonized System of Classification and Labelling of Chemicals (GHS), Ninth Revised Edition." United Nations, Geneva. [↗] GHS
  3. Goldfrank, Lewis R., Robert S. Hoffman, Mary Ann Howland, et al.. 2019. "Goldfrank's Toxicologic Emergencies, 11th ed.." McGraw-Hill Education, New York. ISBN 978-1-25-985961-8. Erste Hilfe, Toxikologie
  4. National Institute for Occupational Safety and Health (NIOSH). 2023. "NIOSH Pocket Guide to Chemical Hazards (DHHS Publ. 2005-149)." U.S. Department of Health and Human Services / CDC, Cincinnati, OH. [↗] Erste Hilfe, PSA, Toxikologie
  5. European Committee for Standardization (CEN). 2016. "EN 374-1:2016 — Protective gloves against dangerous chemicals and micro-organisms." CEN, Brussels. [↗] PSA
  6. UNECE. 2023. "European Agreement Concerning the International Carriage of Dangerous Goods by Road (ADR 2025)." United Nations, Geneva. [↗] Entsorgung, Rechtsvorschriften
  7. National Fire Protection Association (NFPA). 2022. "NFPA 400 — Hazardous Materials Code." NFPA, Quincy, MA. [↗] Lagerung
  8. Urben, P.G. (ed.). 2017. "Bretherick's Handbook of Reactive Chemical Hazards, 8th ed.." Butterworth-Heinemann / Elsevier, Oxford. [↗] Lagerung
  9. Ministerstwo Klimatu i Środowiska RP. 2023. "Baza danych o produktach i opakowaniach oraz o gospodarce odpadami (BDO)." Ministerstwo Klimatu i Środowiska, Warszawa. Nationale Vorschriften — Polen [↗] Entsorgung
  10. International Agency for Research on Cancer (IARC / WHO). 2024. "IARC Monographs on the Identification of Carcinogenic Hazards to Humans — List of Classifications." WHO, Lyon. [↗] Toxikologie

Registerkarten mit eigenen Referenzen (Emergency, PPE, Storage, Waste) enthalten zusätzliche bibliografische Einträge in ihren jeweiligen Abschnitten.

📈 Analytische Statistik (t-Test · RSD · Grubbs · Q-Dixon) ICH Q2

Fügen Sie eine Serie von Messwiederholungen ein (CSV oder eine Zahl pro Zeile). Der Rechner berechnet Mittelwert, Standardabweichung und 95% CI und erkennt Ausreißer (Grubbs + Dixon Q).

Trennzeichen: Komma, Leerzeichen, Tab, Zeilenumbruch. Min. 3 Messungen.
📐 Statistische Formeln
  • x̄ = Σxᵢ / n — arithmetisches Mittel
  • s² = Σ(xᵢ - x̄)² / (n-1) — Stichprobenvarianz
  • s = √s² — Standardabweichung
  • RSD% = (s / x̄) × 100% — relative Standardabweichung
  • CI₉₅ = x̄ ± t(0.05, n-1) × s / √n — Student's t
  • G = |xᵢ - x̄| / s — Grubbs-Test
  • Q = |xsuspect - xnearest| / |xmax - xmin| — Dixon Q-test

Quelle: ICH Q2(R2) Validation of Analytical Procedures · ICH PDF ↗

🧪 Puffer-Rezept-Rechner EINZIGARTIG
Literatur: pKa-Werte aus Goldberg NIST 81 · CRC Handbook 100th ed. · Stoll & Blanchard 1990 (DOI)

Wählen Sie einen Puffer aus der Liste von 20 gängigen Systemen → geben Sie den Ziel-pH-Wert ein → Sie erhalten ein exaktes Rezept mit den einzuwiegenden Massen.

Schritt 1: Puffersystem wählen

📜 Rezeptverlauf (letzte 10)
📅 Project Planner — Manager für Laborexperimente NEU

Planen Sie Ihr gesamtes Laborprojekt: Fügen Sie Experimente mit Reagenzien, Wiederholungen und Dauer hinzu. Sie erhalten ein Gantt-Diagramm, eine Einkaufsliste (mit Links zum Shop!), ein Budget mit 10% Reserve und eine GHS-Risikomatrix.

🧪 Löslichkeit und Lösungsmittelkompatibilität
Molekül
Vanillin
Formel
C8H8O3
logP (XLogP3)
1.20
Masse (g/mol)
152.15
Polarität
Mäßig

⚠️ GC-Schätzung (Hoftyzer–Van Krevelen). Keine HSP-Literaturdaten für diese CAS — Genauigkeit ±2 MPa½. Experimentell verifizieren.

Ra < R₀ = good miscibility · Ra < 1,5×R₀ = borderline · above = poor (R₀ — radius of the Hansen sphere of this molecule) For this molecule R₀ = 8..

Lösungsmittel Compat. Ra Visuell GC-MS HPLC Anwendungen Referenzen
Water (H₂O)11 g/L (pomiar)—
✗ NoA (aqueous) (RP)
buffercell cultureanalyticalextraction (hydrophilic)
Ethanol (EtOH)——no basis✗ NoA/B modifier (RP/NP)
extractionspectroscopy (UV-Vis)synthesisHPLC modifier
Methanol (MeOH)——no basis✗ NoA/B (RP) (RP)
HPLC (eluent)LC-MSKarl FischerUV-transparent to 205 nm
Acetone——no basis✗ NoB modifier (NP)
GC headspacecrystallisationdegreasingsynthesis
Acetonitrile (ACN)——no basis✗ NoB (RP) (RP)
HPLC eluent (gold standard)LC-MS (low UV cut-off, 190 nm)peptide analysis
DMSO——no basis✗ NoN/A (N/A)
NMR (d6-DMSO)cell biology (cryopreservation)drug deliverysynthesis
THF——no basis✗ NoB (NP) (NP)
GPC/SEC (polymer analysis)Grignard synthesisorganometallics
DCM (CH₂Cl₂)——no basis✓ YesB (NP) (NP)
extractionNP-HPLCGC-MScrystallisation (anti-solvent)
Chloroform (CHCl₃)——no basis✓ YesN/A (toxic) (N/A)
NMR (CDCl3)lipid extraction (Folch method)NP-TLC
Hexane——no basis✓ YesA (NP) (NP)
NP-HPLCoil extraction (lipids)GC-MSTLC (NP)
Toluene——no basis✓ YesB (NP) (NP)
NMR (d8-toluene)synthesisazeotropic drying (Dean-Stark)
📚 Wissenschaftliche Referenzen für Lösungsmittel (Chicago Author-Date) — zum Aufklappen klicken

11 solvents · 54 full citations (NIST/CRC/IARC/Hansen/Reichardt/Smallwood/Wypych/Armarego/Snyder/GESTIS) — below.

Water (H₂O)
  1. NIST — NIST Chemistry WebBook — Water (CAS 7732-18-5)
  2. CRC — CRC Handbook of Chemistry and Physics, 104th ed., Sec. 8 (Properties of Water)
  3. IAPWS — IAPWS Release on Static Dielectric Constant of Water
  4. Reichardt 2011 — Solvents and Solvent Effects in Organic Chemistry
  5. GESTIS — GESTIS Substance Database — Water
Ethanol (EtOH)
  1. NIST — NIST Chemistry WebBook — Ethanol (CAS 64-17-5)
  2. CRC — CRC Handbook — Ethanol physical constants
  3. Snyder & Kirkland — Modern Liquid Chromatography — Ethanol eluotropic
  4. Smallwood — Handbook of Organic Solvent Properties — Ethanol
  5. GESTIS — GESTIS Substance Database — Ethanol
Methanol (MeOH)
  1. NIST — NIST Chemistry WebBook — Methanol (CAS 67-56-1)
  2. CRC — CRC Handbook — Methanol physical constants
  3. Snyder & Kirkland — Modern Liquid Chromatography — MeOH eluotropic, eo=0.95
  4. GESTIS — GESTIS Substance Database — Methanol
Acetone
  1. NIST — NIST Chemistry WebBook — Acetone (CAS 67-64-1)
  2. CRC — CRC Handbook — Acetone physical & thermodynamic constants
  3. Hansen 2007 — Hansen Solubility Parameters — Acetone (dD=15.5, dP=10.4, dH=7.0)
  4. Smallwood — Handbook of Organic Solvent Properties — Acetone
  5. GESTIS — GESTIS Substance Database — Acetone
Acetonitrile (ACN)
  1. NIST — NIST Chemistry WebBook — Acetonitrile (CAS 75-05-8)
  2. CRC — CRC Handbook — Acetonitrile constants
  3. Snyder & Kirkland — Modern Liquid Chromatography — ACN gold-standard HPLC eluent
  4. Reichardt 2011 — Solvents and Solvent Effects — ACN dipolar aprotic
  5. GESTIS — GESTIS Substance Database — Acetonitrile
DMSO
  1. NIST — NIST Chemistry WebBook — DMSO (CAS 67-68-5)
  2. Wypych 2019 — Handbook of Solvents Vol. 1 — DMSO comprehensive properties
  3. Hansen 2007 — HSP — DMSO (dD=18.4, dP=16.4, dH=10.2)
  4. Reichardt 2011 — Solvents and Solvent Effects — DMSO E_T(30)=45.1, dipolar aprotic
  5. GESTIS — GESTIS Substance Database — DMSO
THF
  1. NIST — NIST Chemistry WebBook — THF (CAS 109-99-9)
  2. Armarego 2009 — Purification of Laboratory Chemicals — THF drying & peroxide test
  3. Hansen 2007 — Hansen Solubility Parameters — THF (dD=16.8, dP=5.7, dH=8.0)
  4. Smallwood — Handbook of Organic Solvent Properties — THF
  5. GESTIS — GESTIS Substance Database — Tetrahydrofuran
DCM (CH₂Cl₂)
  1. NIST — NIST Chemistry WebBook — Dichloromethane (CAS 75-09-2)
  2. IARC 71 — IARC Monograph 71 — DCM (Group 2A carcinogen)
  3. Hansen 2007 — Hansen Solubility Parameters — DCM (dD=18.2, dP=6.3, dH=6.1)
  4. Reichardt 2011 — Solvents and Solvent Effects — DCM polarity index
  5. GESTIS — GESTIS Substance Database — Dichloromethane
Chloroform (CHCl₃)
  1. NIST — NIST Chemistry WebBook — Chloroform (CAS 67-66-3)
  2. IARC 73 — IARC Monograph 73 — Chloroform (Group 2B carcinogen)
  3. Hansen 2007 — Hansen Solubility Parameters — CHCl3 (dD=17.8, dP=3.1, dH=5.7)
  4. Reichardt 2011 — Solvents and Solvent Effects — CHCl3 H-bond donor strength
  5. GESTIS — GESTIS Substance Database — Chloroform
n-Hexane
  1. NIST — NIST Chemistry WebBook — n-Hexane (CAS 110-54-3)
  2. ATSDR n-Hexane — ATSDR Toxicological Profile for n-Hexane — neuropatia obwodowa (n-Heksan NIE jest kancerogenem IARC)
  3. Hansen 2007 — Hansen Solubility Parameters — n-Hexane (dD=14.9, dP=0, dH=0)
  4. Snyder & Kirkland — Modern Liquid Chromatography — n-Hexane NP standard, eo=0.00
  5. GESTIS — GESTIS Substance Database — n-Hexane
Toluene
  1. NIST — NIST Chemistry WebBook — Toluene (CAS 108-88-3)
  2. IARC 71 — IARC Monograph 71 — Toluene
  3. Hansen 2007 — Hansen Solubility Parameters — Toluene (dD=18.0, dP=1.4, dH=2.0)
  4. Smallwood — Handbook of Organic Solvent Properties — Toluene
  5. GESTIS — GESTIS Substance Database — Toluene
Löslichkeitstheorie (angewendet in der Verträglichkeitsvorhersage):
  1. Yalkowsky, Samuel H., and Shri C. Valvani. 1980. "Solubility and Partitioning I: Solubility of Nonelectrolytes in Water." Journal of Pharmaceutical Sciences 69 (8): 912–922. https://doi.org/10.1002/jps.2600690814 — General Solubility Equation (GSE): logS = 0.5 − logP − 0.01(MP−25).
  2. Hansen, Charles M. 2007. Hansen Solubility Parameters: A User's Handbook. 2nd ed. CRC Press. https://doi.org/10.1201/9781420006834 — HSP-Triplett (dD, dP, dH) + Ra-Formel.
  3. Stefanis, E., and C. Panayiotou. 2008. "Prediction of Hansen Solubility Parameters with a New Group-Contribution Method." Int J Thermophys 29: 568–585. https://doi.org/10.1007/s10765-008-0415-z
  4. Reichardt, Christian, and Thomas Welton. 2011. Solvents and Solvent Effects in Organic Chemistry. 4th ed. Wiley-VCH. https://doi.org/10.1002/9783527632220 — E_T(30) polarity scale, solwatochromia.
  5. Snyder, Lloyd R., Joseph J. Kirkland, and John W. Dolan. 2010. Introduction to Modern Liquid Chromatography. 3rd ed. Wiley. https://doi.org/10.1002/9780470508183 — Eluotropic series, polarity index.
  6. Van Krevelen, D. W., and K. Te Nijenhuis. 2009. Properties of Polymers. 4th ed. Elsevier. https://doi.org/10.1016/B978-0-08-054819-7.X0001-5 — Hoftyzer–Van Krevelen group contribution dla dD/dP/dH z SMILES.
  7. Marcus, Yizhak. 1998. The Properties of Solvents. Wiley Series in Solution Chemistry, Vol. 4. ISBN 9780471983699 — Vollständige tabellarische Sammlung von 250+ Lösungsmitteln (ε, μ, Donizität, Akzeptorzahlen).
  8. PubChem Compound Database — CAS 121-33-5 lookup ↗ — logP (XLogP3), water solubility experimental + predicted.

Vollständige Bibliografie im Akkordeon REFERENZEN (am Ende der Seite) — Chicago Manual of Style 17th ed., Author-Date.

⚗️ Reaktionskompatibilität prüfen
2 0 0
Gesundheit: 2/4
Entflammbarkeit: 0/4
Reaktivität: 0/4
Gemäß NFPA 704 / berechnet aus H-Sätzen

Prüfen Sie, ob Vanillin mit einem anderen Reagenz verträglich ist

📦 Lagerverträglichkeitsmatrix
Acids Regeln Oxidationsmittel Entzündbar Giftig Gazy
Acids ✓ ✗ ✗ ✗ ⚠ ✗
Regeln ✗ ✓ ⚠ ⚠ ⚠ ⚠
Oxidationsmittel ✗ ⚠ ✓ ✗ ⚠ ✗
Entzündbar ✗ ⚠ ✗ ✓ ⚠ ✗
Giftig ⚠ ⚠ ⚠ ⚠ ✓ ⚠
Gazy ✗ ⚠ ✗ ✗ ⚠ ✓
✓ Gemeinsame Lagerung möglich · ⚠ Vorsicht · ✗ NICHT zusammen lagern · OSHA Chemical Segregation ↗

Verträglichkeitsdaten aus: Bretherick's Handbook (7th ed.) ↗, GESTIS ↗, ECHA REACH ↗, NFPA 704 ↗

🧮 Laborrechner (8)
Verdünnung (C₁V₁=C₂V₂)
Molarität (M=n/V)
pH-Puffer (Henderson-Hasselbalch)
Beer-Lambert (A=εcl)
Masse → Mol
Konzentration % → M
ppm → mg/L
Temperatur C↔F↔K

Verifizierte Formeln: IUPAC Gold Book ↗, DOI ↗

📊 Spektroskopische Spektrendatenbanken
📋 Laborprotokoll-Generator

Protokoll erstellt auf Grundlage von: GHS SDS, Aldrich Lab Guide ↗

🏷️ Etiketten-Generator (QR)
Vanillin• 4-Hydroxy-3-methoxybenzaldehyde / Lioxin• IUPAC: 4-hydroxy-3-methoxybenzaldehyde• CAS: 121-33-5• EC: 204-465-2• Formel: C8H8O3• Masse: 152.15 g/molACHTUNGGHS-GEFAHRENHINWEISE:(Selbsteinstufung der Lieferanten — unverbindlich)H319 H302 H411P301+P317 P302+P352 P305+P351+P338 P333+P317 P337+P317 P362+P364 P321P330 P391 P280 P501 P261 P264+P265 P264 P270 P272 P273Nonsensia Ltd124-128 City Road, EC1V 2NX London[email protected]molgod.orgCharge-Nr.: Nettomasse:
Deskryptory Lipinskiego (struktura)
ADMET-Vorhersagen werden geladen…
🧪 Assistent zur Lösungsherstellung (Smart Prep)

Geben Sie ein, was Sie zubereiten möchten — ich erstelle eine SOP

Beispiele unten — zum Einfügen anklicken:
Fertige Rezepte:
📚 Überblick über die wissenschaftliche Literatur — CAS 121-33-5
⭐ Wichtigste Erkenntnisse (wissenschaftliche Literatur) 9 Publikationen
🏆 CAS 121-33-5 — multi-criteria ranking (W12): 30% Zitierungen · 20% Aktualität · 20% Thema · 15% historisch · 15% Open Access.
  1. #1
    Stoff H (2024) · NTM
    Warum es wichtig ist: Aktuell (2024) · open access
    SCORE 6.25 Mechanismus Open Access DOI ↗ PubMed ↗
  2. #2
    Santos LDF, Lautru S, Pernodet JL (2024) · Biomolecules
    Warum es wichtig ist: Aktuell (2024) · Übersichtsarbeit · open access
    SCORE 6.25 Übersicht Open Access DOI ↗ PubMed ↗
  3. #3
    Zhang M, Subramaniyan S, Hakkarainen M (2025) · Macromolecular rapid communications
    Warum es wichtig ist: Aktuell (2025) · open access
    SCORE 6.25 Mechanismus Open Access DOI ↗ PubMed ↗
  4. #4
    Kamaly NA, Kamel AS, Sadik NA et al. (2025) · Molecular neurobiology
    Warum es wichtig ist: Aktuell (2025) · open access
    SCORE 6.25 Mechanismus Open Access DOI ↗ PubMed ↗
  5. #5
    Liu Y, Sun L, Huo YX et al. (2023) · Microbial cell factories
    Warum es wichtig ist: Aktuell (2023) · Übersichtsarbeit · open access
    SCORE 6.15 Übersicht Open Access DOI ↗ PubMed ↗
  6. #6
    Rakoczy K, Szlasa W, Saczko J et al. (2021) · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
    Warum es wichtig ist: Übersichtsarbeit · open access
    SCORE 5.55 Übersicht Open Access DOI ↗ PubMed ↗
  7. #7
    Ma Q, Liu L, Zhao S et al. (2022) · World journal of microbiology & biotechnology
    Warum es wichtig ist: Übersichtsarbeit
    SCORE 5.2 Übersicht DOI ↗ PubMed ↗
  8. #8
    Abdelghafour AM, Mahrous M, Zaher ME (2025) · Food & function
    Warum es wichtig ist: Aktuell (2025)
    SCORE 4 Mechanismus DOI ↗ PubMed ↗
  9. #9
    Kojder PL, Erickson CL (2021) · Dermatitis : contact, atopic, occupational, drug
    Warum es wichtig ist: Ausgewählt nach einem Multikriterien-Score (Zitierungen + Aktualität + Thema + historisch + OA).
    SCORE 3.3 Mechanismus DOI ↗ PubMed ↗

Why this page can be checked

Identity

CAS, EC and molecular formula, resolved across the identifier systems a buyer uses. The count of systems resolved is shown, so you can see how well characterised this substance is rather than assuming.

Data

Every physicochemical value carries the source it came from and the date that source was read. Open any of them.

Classification

Read against the harmonised entry where one exists, with the index number stated. Self-classification is shown separately and labelled.

Regulatory

Inventory, restriction, authorisation and candidate-list status, each stated individually. Where a status is not established, this page says so — it never says no restrictions apply.

Documentation

Which documents exist, at what review level, in which languages, and when each was issued.

Supplier

Who is selling this, and what they have published about themselves.

Nothing on this page is a certification. It is a record you can audit.

Two guarantees, both with their limits stated

The Gap Report Guarantee

If the available evidence cannot support a defensible document for your CAS number and product specification, we will not invent the missing values. You receive a documented gap report and choose: a refund, store credit, or the report on its own.

A visible gap is worth more than a plausible number, because the plausible number is the one that fails when somebody checks it.

The Re-issue Promise

If a signed card is rejected by an authority or by a customer’s compliance officer on one of the points we checked and reported as passed, we re-issue it corrected at no charge and credit the original fee.

This covers the checks we performed and named. It does not cover registration status, tonnage, or your role in the supply chain — those are not ours to hold, and a guarantee that pretended otherwise would be worth nothing.

For vanillin (CAS 121-33-5) the documentation obligation begins before the first shipment. This page sets out what the safety data sheet has to establish.

vanillin (CAS 121-33-5) at a glance

  • Substance – vanillin
  • CAS number – 121-33-5
  • EC number – 204-465-2
  • CLP Annex VI – no harmonised entry
  • Classification basis – self-classification from aggregated ECHA C&L Inventory notifications (CLP Art. 4(3))
  • Documentation issued – safety data sheet in REACH Annex II structure; working draft or signed card
  • What is supplied – a document. MolGod.org does not sell, supply or ship chemical substances.

What is the CLP classification of vanillin?

Vanillin has no harmonised entry in CLP Annex VI, so there is no binding classification to copy. The sheet carries the classification derived from aggregated notifications in the ECHA C&L Inventory and states that basis in section 2; the importer remains responsible for confirming it against the manufacturer’s data.

Disposal route and waste classification

Disposal of vanillin and of its packaging is section 13, and it has to align with the classification: a substance with an aquatic hazard cannot be routed to drain, and the waste code assigned by the holder follows from the hazard profile, not from convenience.

How is vanillin classified for road, sea and air transport?

Section 14 for CAS 121-33-5 carries the UN number, proper shipping name, class, packing group and environmental hazard where these apply. Where the substance is not dangerous for carriage, the section says so explicitly rather than being left empty — an empty section 14 reads as an omission, not as an absence of hazard.

Which version do you need?

SDS Working Draft

€49.99

  • Delivered automatically after payment, by e-mail
  • Full 16-section REACH Annex II structure
  • Classification against ECHA CLP Annex VI
  • Public-source data with references
  • Unresolved gaps flagged, never filled by guesswork
  • For internal drafting and supplier review. Unsigned; supplier-specific fields may need completing.

Best for

  • Seeing what the document will contain before you commit
  • Comparing what a supplier sent you against the register
  • Finding the gaps in a sheet you already hold
  • Preparing an internal file before an export decision
  • Substances you handle but do not yet sell
Recommended when the document leaves your company

Expert-Reviewed SDS

€249.99

  • Everything in the Working Draft
  • Reviewed by a competent person under Annex II, section by section
  • Adapted to your company, product grade and identified use
  • Destination market and language checked
  • Transport section reviewed for the mode you request
  • Five rounds of corrections applied to your instructions
  • Within 72 hours of receiving complete input.

Best for

  • Any document that leaves your company
  • A customer or distributor who asked for the sheet
  • Paperwork travelling with an export shipment
  • A sheet an inspector or authority may read
  • Replacing a sheet a customer has already rejected
If you are unsure, read down the left column and stop at the first line that describes your situation.
What the document is for Working Draft
€49.99		 Expert-Reviewed
€249.99
Internal drafting and review YesYes
Checking a sheet a supplier sent you YesYes
Sent to your customer Not written for thisYes
Travels with an export shipment Not written for thisYes
Read by an inspector or authority Not written for thisYes
Adapted to your company, grade and identified use NoYes
Signed and dated by the reviewer NoYes
When you get it Immediately after paymentWithin 72 hours of complete input

Nothing stops you sending a draft to anyone. "Not written for this" means exactly that: it carries no signature and no fields adapted to your company, so it will not answer the questions the recipient is about to ask.

What the signature means

Who prepares the document
The document is generated by the MolGod engine from ECHA CLP Annex VI and the cited public sources, then read section by section by a qualified scientific reviewer with a degree in chemistry or a related scientific field.
What the review covers
The sheet is read section by section against the REACH Annex II structure. GHS classification and transport entries are checked against the sources cited in the document, and the sheet is adapted to the company, product grade and identified use you provide.
What is NOT verified
We do not test your material and we cannot confirm what is physically in your container: composition, concentration, impurities or manufacturing route. Those come from you and are reproduced as supplied.
What the signature is — and is not
The signature records that a qualified scientific reviewer read the document. It is not a government approval, not an ECHA approval, and not a legal certification — no such certification exists for safety data sheets in the EU. A signature does not by itself make a document legally valid or make your business compliant.
What you receive
A PDF in the 16-section REACH Annex II structure, signed and dated, with version information and a list of anything we could not establish. Five rounds of corrections are included.
Delivery
Within 72 hours of receiving complete input from you. The clock pauses whenever we are waiting on an answer.
Refunds
Full refund before review begins. If the evidence is insufficient, you choose a refund, store credit or a gap report. See the refund policy.

No fabricated-data guarantee. If the available evidence is insufficient to support a defensible document for this CAS number and your product specification, we will not invent the missing values. You may choose a refund, store credit or a documented gap report.

The supplier placing the substance or mixture on the market remains responsible for ensuring that the final safety data sheet matches the material, its identified uses and their legal role in the supply chain.

Not sure which one fits? Ask for a free screening of a sheet you already hold.

Related products

📄 Analysenzertifikate (CoA) CAS 121-33-5 keine

Keine Zertifikate für dieses Produkt in der Datenbank.

📚 Wissenschaftliche Referenzen (Chicago Author-Date) — zum Aufklappen klicken

Standards für Chargenmanagement und Laborzertifizierung — 13 unabhängige Quellen (ICH Q1/Q3/Q6/Q7/Q10 + ISO 17025 + WHO TRS + 21 CFR 211 + EMA + USP + Ph.Eur. + PIC/S + IPEC-PQG).

  1. International Council for Harmonisation (ICH). 2000. "Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients." ICH Expert Working Group. [Link ↗] — GMP for APIs — adopted by EMA, FDA, MHLW
  2. International Organization for Standardization. 2017. "ISO/IEC 17025:2017 General requirements for the competence of testing and calibration laboratories." ISO. [Link ↗] — Lab accreditation standard underpinning every CoA
  3. World Health Organization. 2010. "WHO Good Manufacturing Practices for Pharmaceutical Products: Main Principles (WHO Technical Report Series No. 957, Annex 3)." WHO Press. [Link ↗] — WHO TRS No. 957 — global reference for GMP
  4. International Council for Harmonisation (ICH). 2003. "ICH Q1A(R2): Stability Testing of New Drug Substances and Products." International Council for Harmonisation. [Link ↗] — Source for batch shelf-life and retest dating
  5. International Council for Harmonisation (ICH). 2006. "ICH Q3A(R2): Impurities in New Drug Substances." ICH. [Link ↗]
  6. International Council for Harmonisation (ICH). 1999. "ICH Q6A: Specifications for New Drug Substances and Products." ICH. [Link ↗] — CoA acceptance-criteria specification standard
  7. International Council for Harmonisation (ICH). 2008. "ICH Q10: Pharmaceutical Quality System." ICH. [Link ↗]
  8. U.S. Food and Drug Administration. 2024. "21 CFR Part 211: Current Good Manufacturing Practice for Finished Pharmaceuticals." US Code of Federal Regulations. [Link ↗] — US legal mandate (Subpart J — Records and Reports)
  9. European Medicines Agency. 2014. "Guideline on Process Validation for Finished Products — Information and Data to Be Provided EMA/CHMP/CVMP/QWP/BWP/70278/2012." European Medicines Agency. [Link ↗]
  10. United States Pharmacopeial Convention. 2024. "United States Pharmacopeia and National Formulary, USP 47-NF 42." USP. [Link ↗]
  11. European Pharmacopoeia Commission. 2024. "European Pharmacopoeia 11th Edition." Council of Europe — EDQM. [Link ↗]
  12. Pharmaceutical Inspection Co-operation Scheme (PIC/S). 2021. "Guide to Good Manufacturing Practice for Medicinal Products PE 009-15." PIC/S Secretariat, Geneva. [Link ↗] — Cross-recognized GMP for 54 inspectorates worldwide
  13. International Pharmaceutical Excipients Council (IPEC) and Pharmaceutical Quality Group (PQG). 2017. "Joint IPEC-PQG Good Manufacturing Practices Guide for Pharmaceutical Excipients." IPEC-Americas. [Link ↗] — Excipient-grade CoA standard for non-API ingredients
📜 Patente (öffentliche Metadaten) keine Daten

Derzeit wurden keine öffentlichen Patent-Metadaten für diese Substanz in Crossref / OpenAlex gefunden. Die Daten werden nach der nächsten Cache-Aktualisierung automatisch ergänzt (24h).

📚 Referenzen (Chicago Author-Date) — zum Aufklappen klicken
  1. Zhang M, Subramaniyan S, Hakkarainen M. (2025). "Divanillin Cross-Linked Recyclable Cellulose Networks.". Macromolecular rapid communications. https://doi.org/10.1002/marc.202401094
  2. Kamaly NA, Kamel AS, Sadik NA et al.. (2025). "Milnacipran and Vanillin Alleviate Fibromyalgia-Associated Depression in Reserpine-Induced Rat Model: Role of Wnt/β-Catenin Signaling.". Molecular neurobiology. https://doi.org/10.1007/s12035-025-04723-w
  3. Abdelghafour AM, Mahrous M, Zaher ME. (2025). "Vanillin alleviates oxidative stress-mediated neuronal pyroptosis induced in rats by isoproterenol via SIRT1/NOX4/ROS/TXNIP/NLRP3 signaling pathway.". Food & function. https://doi.org/10.1039/d4fo06458e
  4. Santos LDF, Lautru S, Pernodet JL. (2024). "Genetic Engineering Approaches for the Microbial Production of Vanillin.". Biomolecules. https://doi.org/10.3390/biom14111413
  5. Stoff H. (2024). "Paulina S. Gennermann 2023: Eine Geschichte mit Geschmack. Die Natur synthetischer Aromastoffe im 20. Jahrhundert am Beispiel Vanillin und Lisa Haushofer 2022: Wonder Foods: The Science and Commerce of Nutrition.". NTM. https://doi.org/10.1007/s00048-024-00384-3
  6. Liu Y, Sun L, Huo YX et al.. (2023). "Strategies for improving the production of bio-based vanillin.". Microbial cell factories. https://doi.org/10.1186/s12934-023-02144-9
  7. Ma Q, Liu L, Zhao S et al.. (2022). "Biosynthesis of vanillin by different microorganisms: a review.". World journal of microbiology & biotechnology. https://doi.org/10.1007/s11274-022-03228-1
  8. Rakoczy K, Szlasa W, Saczko J et al.. (2021). "Therapeutic role of vanillin receptors in cancer.". Advances in clinical and experimental medicine : official organ Wroclaw Medical University. https://doi.org/10.17219/acem/139398
  9. Kojder PL, Erickson CL. (2021). "Airborne Allergic Contact Dermatitis to Vanillin.". Dermatitis : contact, atopic, occupational, drug. https://doi.org/10.1097/DER.0000000000000677
  10. World Intellectual Property Organization. 2024. "Patent Cooperation Treaty (PCT)." https://www.wipo.int/pct/.
  11. U.S. Patent and Trademark Office. 2024. "USPTO Patent Public Search." https://ppubs.uspto.gov/.
  12. European Patent Office. 2024. "Espacenet Patent Search." https://worldwide.espacenet.com/.
  13. Newman, David J., and Gordon M. Cragg. 2020. "Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019." Journal of Natural Products 83 (3): 770-803.
  14. Davies, Mark, Michał Nowotka, George Papadatos, et al. 2015. "ChEMBL Web Services: Streamlining Access to Drug Discovery Data and Utilities." Nucleic Acids Research 43 (W1): W612-W620.
  15. Bickerton, G. Richard, Gaia V. Paolini, Jérémy Besnard, Sorel Muresan, and Andrew L. Hopkins. 2012. "Quantifying the Chemical Beauty of Drugs." Nature Chemistry 4 (2): 90-98.
  16. Meanwell, Nicholas A. 2011. "Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design." Journal of Medicinal Chemistry 54 (8): 2529-2591.
  17. Ertl, Peter, and Ansgar Schuffenhauer. 2009. "Estimation of Synthetic Accessibility Score of Drug-Like Molecules Based on Molecular Complexity and Fragment Contributions." Journal of Cheminformatics 1: 8.
  18. Hopkins, Andrew L., and Colin R. Groom. 2002. "The Druggable Genome." Nature Reviews Drug Discovery 1 (9): 727-730.
  19. Allison, John R., and Mark A. Lemley. 1998. "Empirical Evidence on the Validity of Litigated Patents." AIPLA Quarterly Journal 26 (3): 185-275.
  20. Patani, George A., and Edmond J. LaVoie. 1996. "Bioisosterism: A Rational Approach in Drug Design." Chemical Reviews 96 (8): 3147-3176.
  21. Lerner, Josh. 1994. "The Importance of Patent Scope: An Empirical Analysis." RAND Journal of Economics 25 (2): 319-333.

REST: /wp-json/molgod/v1/patents/121-33-5?status=active&limit=10

Daten von PubChemQuelle: PubChem (NIH) · ChEMBL
📤 Betten Sie dieses Molekül auf Ihrer Website ein

Haben Sie einen Blog, ein Forum oder einen wissenschaftlichen Dienst? Betten Sie das interaktive 3D-Molekül auf Ihrer Website ein — jeder Ihrer Leser sieht es, und darunter gibt es einen Link zu unserem Shop, wo er das Reagenz kaufen kann.

🔗 HTML-iframe-Code (am einfachsten — funktioniert überall)

Kopieren Sie ihn und fügen Sie ihn in den HTML-Editor Ihrer Website ein:

Passen Sie width und height an Ihr Layout an.

⚙ WordPress Shortcode (für andere Shops mit MOL-GOD)

🌐 Direktlink (für E-Mails, Chats, LinkedIn, Twitter)

LinkedIn Twitter/X Facebook
QR code CAS 121-33-5

📱 QR code (zum Druck auf Flyern / Etiketten / Katalogen)

Platzieren Sie ihn in einem Produktkatalog, auf einem Flaschenetikett oder einem Flyer. Der Kunde scannt ihn — sieht das 3D-Molekül auf seinem Telefon, mit einem Link zu Ihrem Shop.

⬇ PNG herunterladen

🖼 Open Graph image (für Social-Media-Meta-Tags)

Wenn Sie den Link teilen, ruft Facebook/LinkedIn/Discord automatisch die Bildvorschau ab:

Preview
📋 Lizenz: Der Embed behält einen Backlink zu MolGod (erforderlich — der Shop ist die Datenquelle). Chemische Daten stammen von PubChem (CC0 — gemeinfrei). Der Embed ist KOSTENLOS für Bildungs-, kommerzielle und Hobbyzwecke.
📚 REFERENZEN (Gesammelte Bibliografie, Chicago Author-Date) 77 Einträge

Alle wissenschaftlichen Quellen, die in den Akkordeons oben für CAS 121-33-5 zitiert werden.Format: Chicago Manual of Style, 17. Aufl., Autor-Datum-System.

🗄️ Wissenschaftliche Datenbanken

  1. NIST. n.d. NIST Chemistry WebBook: CAS 121-33-5. Gaithersburg, MD: National Institute of Standards and Technology. https://webbook.nist.gov/cgi/cbook.cgi?ID=121-33-5.
  2. AIST. n.d. Spectral Database for Organic Compounds (SDBS): CAS 121-33-5. Tsukuba, Japan: National Institute of Advanced Industrial Science and Technology. https://sdbs.db.aist.go.jp/.
  3. Linstrom, Peter J., and William G. Mallard, eds. n.d. NIST Chemistry WebBook: NIST Standard Reference Database Number 69. Gaithersburg, MD: National Institute of Standards and Technology. https://doi.org/10.18434/T4D303.
  4. PubChem. n.d. PubChem Compound Summary: CAS 121-33-5. Bethesda, MD: National Center for Biotechnology Information (NCBI), National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/#query=121-33-5.

📐 Standards / Richtlinien

  1. ICH. 2003. "Stability Testing of New Drug Substances and Products: Q1A(R2)." Geneva: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use. https://database.ich.org/sites/default/files/Q1A%28R2%29%20Guideline.pdf.
  2. National Fire Protection Association (NFPA). 2024. "NFPA 30: Flammable and Combustible Liquids Code." NFPA, Quincy, MA. https://www.nfpa.org/codes-and-standards/all-codes-and-standards/list-of-codes-and-standards/detail?code=30.
  3. Occupational Safety and Health Administration (OSHA). 2023. "29 CFR 1910.106 — Flammable Liquids." U.S. Department of Labor, Federal Register. https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.106.
  4. European Chemicals Agency (ECHA). 2024. "Annex VI to Regulation (EC) No 1272/2008 (CLP) — Harmonised Classification and Labelling." ECHA, Helsinki / Official Journal of the European Union. https://echa.europa.eu/regulations/clp/clp-classification.
  5. European Committee for Standardization (CEN). 2016. "EN 374-1:2016 — Protective gloves against dangerous chemicals and micro-organisms — Part 1: Terminology and performance requirements for chemical risks." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=205:110:::::FSP_PROJECT,FSP_ORG_ID:38536,6080&cs=1B0DAA8B85DF42E4A2C70E5D71F0BFA32.
  6. European Committee for Standardization (CEN). 2001. "EN 166:2001 — Personal eye-protection — Specifications." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=CEN:110:0::::FSP_PROJECT:6541&cs=1F1A4E0A78C4DB6A28DBE2E8C29D89DCF.
  7. European Committee for Standardization (CEN). 2009. "EN 14605:2005+A1:2009 — Protective clothing against liquid chemicals — Performance requirements for clothing with liquid-tight (Type 3) or spray-tight (Type 4) connections." CEN, Brussels. https://standards.cencenelec.eu/dyn/www/f?p=CEN:110:0::::FSP_PROJECT:21581&cs=1A04A2D3C7CC58E9E6CB58D55F7EBFB7E.
  8. National Institute for Occupational Safety and Health (NIOSH). 2017. "Recommendations for Chemical Protective Clothing: A Companion to the NIOSH Pocket Guide." U.S. Department of Health & Human Services / CDC. https://www.cdc.gov/niosh/ncpc/default.html.
  9. Occupational Safety and Health Administration (OSHA). 2011. "Personal Protective Equipment — General requirements." U.S. Department of Labor — 29 CFR 1910.132. https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.132.

📖 Bücher

  1. Hansen, Charles M. 2007. Hansen Solubility Parameters: A User's Handbook, 2nd ed.. Boca Raton, FL: CRC Press. https://www.routledge.com/Hansen-Solubility-Parameters-A-Users-Handbook/Hansen/p/book/9780849372483.
  2. Barton, Allan F. M. 1991. CRC Handbook of Solubility Parameters and Other Cohesion Parameters: 2nd ed.. Boca Raton, FL: CRC Press. https://www.routledge.com/CRC-Handbook-of-Solubility-Parameters-and-Other-Cohesion-Parameters/Barton/p/book/9780849301766.
  3. Connors, Kenneth A., Gordon L. Amidon, and Valentino J. Stella. 1986. Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists, 2nd ed.. New York: Wiley. https://doi.org/10.1002/0471734683.
  4. Rumble, John R., ed. 2019. CRC Handbook of Chemistry and Physics: 100th Edition. Boca Raton, FL: CRC Press. https://hbcp.chemnetbase.com/.
  5. Urben, Peter G. 2017. Bretherick's Handbook of Reactive Chemical Hazards, 8th Edition. Academic Press / Elsevier, Oxford. https://www.sciencedirect.com/book/9780081010594.

📄 Wissenschaftliche Artikel (peer-reviewed)

  1. Stefanis, Emmanuel, and Costas Panayiotou. 2008. "Prediction of Hansen Solubility Parameters with a New Group-Contribution Method." International Journal of Thermophysics 29: 568-585. https://doi.org/10.1007/s10765-008-0415-z.
  2. Stoll, Vincent S., and John S. Blanchard. 1990. "Buffers: Principles and Practice: In Methods in Enzymology, vol. 182." San Diego: Academic Press. https://doi.org/10.1016/0076-6879(90)82008-P.

🌐 Websites

  1. ECHA. 2023. "Guidance on the Application of the CLP Criteria." European Chemicals Agency. https://echa.europa.eu/guidance-documents/guidance-on-clp.
  2. European Parliament. 2006. "Regulation (EC) No 1907/2006 (REACH)." Official Journal of the European Union L 396: 1–849.
  3. ECHA. 2023. "Candidate List of Substances of Very High Concern for Authorisation." European Chemicals Agency. https://echa.europa.eu/candidate-list-table.
  4. European Parliament. 2008. "Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of Substances and Mixtures (CLP)." Official Journal of the European Union L 353: 1–1355.
  5. ECHA. 2017. "Guidance on the Compilation of Safety Data Sheets." Version 3.1. European Chemicals Agency. ECHA-17-G-01-EN. https://echa.europa.eu/documents/10162/23047722/sds_en.pdf.
  6. ECHA. 2022. "Restrictions Under REACH — Annex XVII." European Chemicals Agency. https://echa.europa.eu/substances-restricted-under-reach.
  7. United Nations. 2021. Globally Harmonized System of Classification and Labelling of Chemicals (GHS). 9th revised ed. ST/SG/AC.10/30/Rev.9. New York and Geneva: United Nations. https://unece.org/ghs-rev9-2021.
  8. ECHA. 2020. "Understanding REACH." European Chemicals Agency. https://echa.europa.eu/regulations/reach/understanding-reach.
  9. United States Pharmacopeial Convention. 2024. "USP <621> Chromatography." In United States Pharmacopeia and National Formulary, USP 47-NF 42. Rockville, MD: USP. https://www.uspnf.com/.
  10. European Pharmacopoeia Commission. 2024. "2.2.46 Chromatographic Separation Techniques." In European Pharmacopoeia, 11th ed. Strasbourg: Council of Europe — EDQM. https://www.edqm.eu/en/european-pharmacopoeia-ph-eur-11th-edition.
  11. International Council for Harmonisation (ICH). 2022. "ICH Q2(R2): Validation of Analytical Procedures." International Council for Harmonisation. https://database.ich.org/sites/default/files/ICH_Q2%28R2%29_Guideline_2022_1130.pdf.
  12. International Council for Harmonisation (ICH). 1996. "ICH Q3A: Impurities in New Drug Substances." International Council for Harmonisation. https://database.ich.org/sites/default/files/Q3A%28R2%29%20Guideline.pdf.
  13. International Organization for Standardization. 2017. "ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories." Geneva: ISO. https://www.iso.org/standard/66912.html.
  14. Kolthoff, Izaak Maurits, and Philip J. Elving, eds. 1978. Treatise on Analytical Chemistry, Part I: Theory and Practice. 2nd ed. New York: Wiley-Interscience.
  15. Skoog, Douglas A., F. James Holler, and Stanley R. Crouch. 2018. Principles of Instrumental Analysis. 7th ed. Boston: Cengage Learning.
  16. Christian, Gary D., Purnendu K. Dasgupta, and Kevin A. Schug. 2014. Analytical Chemistry. 7th ed. Hoboken, NJ: Wiley.
  17. EURACHEM/CITAC. 2012. "Quantifying Uncertainty in Analytical Measurement." 3rd ed. EURACHEM/CITAC Guide CG 4. https://www.eurachem.org/images/stories/Guides/pdf/QUAM2012_P1.pdf.
  18. International Organization for Standardization. 1994. "ISO 5725-2:1994 Accuracy (Trueness and Precision) of Measurement Methods and Results — Part 2: Basic Method for the Determination of Repeatability and Reproducibility of a Standard Measurement Method." Geneva: ISO. https://www.iso.org/standard/11834.html.
  19. Heckert, N. A., and J. J. Filliben. 2003. "NIST/SEMATECH e-Handbook of Statistical Methods." NIST Handbook 151. Gaithersburg, MD: National Institute of Standards and Technology. https://www.itl.nist.gov/div898/handbook/.
  20. Grubbs, Frank E. 1950. "Sample Criteria for Testing Outlying Observations." Annals of Mathematical Statistics 21 (1): 27–58.
  21. Dixon, Wilfrid J. 1950. "Analysis of Extreme Values." Annals of Mathematical Statistics 21 (4): 488–506.
  22. Snedecor, George W., and William G. Cochran. 1989. Statistical Methods. 8th ed. Ames, IA: Iowa State University Press.
  23. Student [William Sealy Gosset]. 1908. "The Probable Error of a Mean." Biometrika 6 (1): 1–25.
  24. International Organization for Standardization. 2005. "ISO 3534-1:2006 Statistics — Vocabulary and Symbols — Part 1: General Statistical Terms and Terms Used in Probability." Geneva: ISO. https://www.iso.org/standard/40145.html.
  25. Thompson, Michael, Stephen L. R. Ellison, and Roger Wood. 2002. "Harmonized Guidelines for Single-Laboratory Validation of Methods of Analysis." Pure and Applied Chemistry 74 (5): 835–855.
  26. United Nations Economic Commission for Europe. 2024. European Agreement Concerning the International Carriage of Dangerous Goods by Road (ADR), Applicable as from 1 January 2025 (ECE/TRANS/352). Geneva: UNECE. https://unece.org/transport/dangerous-goods/adr-2025-edition.
  27. International Air Transport Association. 2026. Dangerous Goods Regulations (DGR). 67th ed. Montreal: IATA. https://www.iata.org/en/programs/cargo/dgr/.
  28. International Maritime Organization. 2024. International Maritime Dangerous Goods (IMDG) Code, 2024 Edition (Amendment 42-24). London: IMO. https://www.imo.org/en/OurWork/Safety/Pages/DangerousGoods-default.aspx.
  29. United Nations. 2025. Recommendations on the Transport of Dangerous Goods: Model Regulations (Orange Book). 24th revised ed. ST/SG/AC.10/1/Rev.24. New York and Geneva: United Nations. https://unece.org/transport/dangerous-goods/un-model-regulations.
  30. International Civil Aviation Organization. 2025. Technical Instructions for the Safe Transport of Dangerous Goods by Air (Doc 9284). 2025–2026 ed. Montreal: ICAO. https://www.icao.int/safety/DangerousGoods/Pages/technical-instructions.aspx.
  31. European Commission. 2014. "Commission Decision 2014/955/EU on the list of waste pursuant to Directive 2008/98/EC." Official Journal of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32014D0955.
  32. Ministerstwo Klimatu i Środowiska Rzeczypospolitej Polskiej. 2020. "Rozporządzenie Ministra Klimatu z dnia 2 stycznia 2020 r. w sprawie katalogu odpadów." Dziennik Ustaw RP 2020 poz. 10. https://isap.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20200000010. Nationale Vorschriften — Polen
  33. Główny Inspektorat Ochrony Środowiska (GIOŚ). 2024. "Baza Danych O Odpadach (BDO) — System rejestracji firm utylizacyjnych." Ministerstwo Klimatu i Środowiska. https://bdo.mos.gov.pl/. Nationale Vorschriften — Polen
  34. Polska — Sejm RP. 2012. "Ustawa z dnia 14 grudnia 2012 r. o odpadach." Dz.U. 2013 poz. 21 (z późn. zm.). https://isap.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20130000021. Nationale Vorschriften — Polen
  35. Furr, A. Keith, ed.. 2000. "CRC Handbook of Laboratory Safety." CRC Press.
  36. Pohanish, Richard P.. 2017. "Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens." Elsevier.
  37. Lewis, Richard J.. 2012. "Sax's Dangerous Properties of Industrial Materials." Wiley.
  38. NIOSH. 2024. "Pocket Guide to Chemical Hazards." U.S. Department of Health and Human Services. https://www.cdc.gov/niosh/npg/.
  39. OSHA. 2024. "Occupational Chemical Database — Hazardous Waste Operations (HAZWOPER)." Occupational Safety and Health Administration. https://www.osha.gov/chemicaldata.
  40. European Parliament and Council. 2008. "Directive 2008/98/EC on waste (Waste Framework Directive)." Official Journal of the European Union L 312/3. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008L0098.
  41. European Parliament and Council. 2009. "Regulation (EC) No 1272/2008 (CLP) on classification, labelling and packaging of substances and mixtures." Official Journal of the European Union L 353. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1272.
  42. United Nations Economic Commission for Europe (UNECE). 2023. "European Agreement concerning the International Carriage of Dangerous Goods by Road (ADR 2025)." UNECE. https://unece.org/transport/standards/transport/dangerous-goods/adr-2025.
  43. IPCS INCHEM. 2024. "International Programme on Chemical Safety — Waste Management Guidelines." WHO/UNEP/ILO. https://www.inchem.org/.
  44. European Parliament and Council. 2006. "Regulation (EC) No 1013/2006 on Shipments of Waste." Official Journal of the European Union L 190: 1–98. https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32006R1013.
  45. International Council for Harmonisation (ICH). 2000. "Q7 Good Manufacturing Practice Guide for Active Pharmaceutical Ingredients." ICH Expert Working Group. https://database.ich.org/sites/default/files/Q7%20Guideline.pdf.
  46. International Organization for Standardization. 2017. "ISO/IEC 17025:2017 General requirements for the competence of testing and calibration laboratories." ISO. https://www.iso.org/standard/66912.html.
  47. World Health Organization. 2010. "WHO Good Manufacturing Practices for Pharmaceutical Products: Main Principles (WHO Technical Report Series No. 957, Annex 3)." WHO Press. https://www.who.int/publications/m/item/trs957-annex3.
  48. International Council for Harmonisation (ICH). 2003. "ICH Q1A(R2): Stability Testing of New Drug Substances and Products." International Council for Harmonisation. https://database.ich.org/sites/default/files/Q1A%28R2%29%20Guideline.pdf.
  49. International Council for Harmonisation (ICH). 2006. "ICH Q3A(R2): Impurities in New Drug Substances." ICH. https://database.ich.org/sites/default/files/Q3A%28R2%29%20Guideline.pdf.
  50. International Council for Harmonisation (ICH). 1999. "ICH Q6A: Specifications for New Drug Substances and Products." ICH. https://database.ich.org/sites/default/files/Q6A%20Guideline.pdf.
  51. International Council for Harmonisation (ICH). 2008. "ICH Q10: Pharmaceutical Quality System." ICH. https://database.ich.org/sites/default/files/Q10%20Guideline.pdf.
  52. U.S. Food and Drug Administration. 2024. "21 CFR Part 211: Current Good Manufacturing Practice for Finished Pharmaceuticals." US Code of Federal Regulations. https://www.ecfr.gov/current/title-21/chapter-I/subchapter-C/part-211.
  53. European Medicines Agency. 2014. "Guideline on Process Validation for Finished Products — Information and Data to Be Provided EMA/CHMP/CVMP/QWP/BWP/70278/2012." European Medicines Agency. https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-process-validation-finished-products-information-data-be-provided-regulatory-submissions-revision-1_en.pdf.
  54. United States Pharmacopeial Convention. 2024. "United States Pharmacopeia and National Formulary, USP 47-NF 42." USP. https://www.uspnf.com/.
  55. European Pharmacopoeia Commission. 2024. "European Pharmacopoeia 11th Edition." Council of Europe — EDQM. https://www.edqm.eu/en/european-pharmacopoeia-ph-eur-11th-edition.
  56. Pharmaceutical Inspection Co-operation Scheme (PIC/S). 2021. "Guide to Good Manufacturing Practice for Medicinal Products PE 009-15." PIC/S Secretariat, Geneva. https://picscheme.org/en/publications.
  57. International Pharmaceutical Excipients Council (IPEC) and Pharmaceutical Quality Group (PQG). 2017. "Joint IPEC-PQG Good Manufacturing Practices Guide for Pharmaceutical Excipients." IPEC-Americas. https://ipecamericas.org/sites/default/files/IPECPQGGMPGuide2017.pdf.
📥 BibTeX herunterladen📥 RIS herunterladenImport in Zotero/Mendeley/EndNote/Papers.
📜 Lizenz und Provenienz
vanillin (CAS 121-33-5), C8H8O3 - 3D ball-and-stick molecular model, engraved element symbols (C H O), MolGod STL previewDownload image

MG_862-948-061-70 · engraved · 259,524 △ · 12 MB · SHA-256 0194fb70856b8c13

3D-Modell herunterladen · ENGRAVED · C H O

vanillin (CAS 121-33-5), C8H8O3 - 3D ball-and-stick molecular model, MolGod STL previewDownload image

MG_862-948-061-70 · normal · 7,904 △ · 386 KB · SHA-256 bf3d41edc5e13128

3D-Modell herunterladen

Modell
vanillin · 121-33-5
InChIKey
MWOOGOJBHIARFG-UHFFFAOYSA-N
Lizenz
CC BY-SA 4.0 International
Namensnennung
MolGod Scientific — vanillin (CAS 121-33-5)
Lizenz- und Provenienzeintrag
vanillin (CAS 121-33-5) →
MolGod-Moleküleintrag
vanillin →
Quelldaten
PubChem CID 1183 ↗
Modellinformationen
STL erzeugt von MolGod · MolGod STL Exporter build 97d4498f28a7 · erzeugt 2026-10-04
SHA-256 (STL)
bf3d41edc5e131288aecf9bc31defe2aea05d6a0337c3add8dd0eaed94bcb338
MD5 (STL)
7ac679ec348b64f50c1bf7b1b32a140a
MolGod Identification Number
MG_862-948-061-70
Transformation
MolGod Scientific Kugel-Stab-Netz
Änderungen
In ein trianguliertes Molekülnetz umgewandelt; Atomkoordinaten und Konnektivität unverändert.
Wikimedia Commons
STL · PNG

Diese Lizenz gilt für das von MolGod erstellte STL-Mesh, nicht automatisch für Quellmaterial Dritter.