bromadiolone (CAS 28772-56-7) — Safety Data Sheet
Safety data sheet documentation for bromadiolone (CAS 28772-56-7), compiled to REACH Annex II with classification read against the harmonised entry in CLP Annex VI (H360D, H330, H310, H300). Two options: a working draft sent by e-mail immediately, or a signed card issued within 72 hours. The item supplied is a document — MolGod.org does not sell, supply or ship chemical substances.
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bromadiolone (ISO) carries a harmonised entry in CLP Annex VI under index 607-[CAS?]. This page covers the safety data sheet issued for it — a document, not a supply of the material.
bromadiolone (CAS 28772-56-7) at a glance
- Substance – bromadiolone
- CAS number – 28772-56-7
- EC number – 249-205-9
- CLP Annex VI index number – 607-[CAS?]
- Also known as – 3-[3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one
- Hazard statements – H360D (may damage the unborn child); H330 (fatal if inhaled); H310 (fatal in contact with skin); H300 (fatal if swallowed); H372 (blood) (causes damage to organs through prolonged or repeated exposure); H400 (very toxic to aquatic life)
- Hazard classes – Repr. 1B, Acute Tox. 1, Acute Tox. 1, Acute Tox. 1, STOT RE 1, Aquatic Acute 1
- Label pictograms – GHS06, GHS08, GHS09
- Signal word – Danger
- Concentration limits / M-factor / ATE – Repr. 1B;H360D: C ≥ 0.003%;STOT RE 1;H372: C ≥ 0.005%;STOT RE 2;H373: 5.0E-4% ≤ C < 0.005%;M = 1;M = 1
- Entry current as of – ATP09
- CMR classification – yes, classified as carcinogenic, mutagenic or toxic for reproduction
- Documentation issued – safety data sheet in REACH Annex II structure; working draft or signed card
- What is supplied – a document. MolGod.org does not sell, supply or ship chemical substances.
Is bromadiolone (ISO) classified as a CMR substance?
CAS 28772-56-7 is classified as a CMR substance (H360D). That status changes the obligations attached to every shipment: workplace exposure documentation, restrictions on supply to the general public, and substitution pressure from downstream users who must justify continued use. A safety data sheet for a CMR substance is read more closely than any other, because the classification itself invites scrutiny.
Documentation demand on the EU market
CAS 28772-56-7 has a recorded presence on the European trading market, which means documentation for it is requested routinely rather than exceptionally. Substances that move in commerce attract repeat scrutiny: the same sheet is read by successive customers, carriers and authorities, and a defect that survives the first reading rarely survives the tenth.
Stability, reactivity and incompatibilities
Section 10 records stability and reactivity for bromadiolone: conditions to avoid, incompatible materials, and hazardous decomposition products. This is the section a laboratory consults before placing two substances on the same shelf.
Disposal route and waste classification
Disposal of bromadiolone and its packaging must comply with section 13 requirements. The substance is classified as posing an aquatic hazard, meaning it cannot be discharged into drains. The waste code assigned by the holder should reflect the hazard profile rather than convenience, ensuring proper management in accordance with regulatory guidelines.
What concentration limits apply to bromadiolone (ISO)?
The harmonised entry for bromadiolone carries specific concentration limits: H360D: C ≥ 0,003 %; H372 (blood): C ≥ 0,005 %; H373 (blood): 0,0005 % ≤ C < 0,005 %. These override the generic cut-off values, so a mixture containing bromadiolone is classified against these figures and not against the default thresholds. M-factor on record: 1. The M-factor multiplies the contribution of this substance in the aquatic hazard calculation for a mixture, which is where it is most often overlooked.
What is the EC number for bromadiolone (ISO)?
Alongside CAS 28772-56-7, this substance carries EC number 249-205-9 and Annex VI index 607-[CAS?]. European documentation is built around the EC number as often as around the CAS: registration dossiers, the candidate list and customs systems key on it. A safety data sheet quoting only one of the two forces every downstream reader to look up the other.
Accidental release and containment
A spill involving substance with CAS number 28772-56-7 must be managed according to Section 6, which should clearly specify the required containment materials and personal protective equipment necessary for personnel approaching the spill site. An operational sheet outlining the cleanup process without detailing the appropriate attire for workers is considered incomplete.
Identifiers that must agree
Identity verification must be conducted prior to hazard assessment. If discrepancies exist between the label, safety data sheet, and certificate regarding the CAS 28772-56-7 number or if the index 607-[CAS?] refers to a location where the name does not match, a reviewer will lose trust in all three documents simultaneously, despite their internal consistency. This is because inconsistencies among these key documentation elements undermine their reliability as a unified source of information.
What Annex VI notes and concentration limits apply to bromadiolone (ISO)?
The register also records Repr. 1B;H360D: C ≥ 0.003%;STOT RE 1;H372: C ≥ 0.005%;STOT RE 2;H373: 5.0E-4% ≤ C < 0.005%;M = 1;M = 1 for this entry. Specific concentration limits, M-factors and acute toxicity estimates override the generic cut-off values, so a mixture calculation that ignores them will classify the mixture wrongly in both directions.
What is the CLP classification of bromadiolone (ISO)?
The harmonised classification for CAS 28772-56-7 carries 7 hazard statements: H360D, H330, H310, H300, H372 (blood), H400, H410. In plain terms this means may damage the unborn child; fatal if inhaled; fatal in contact with skin; fatal if swallowed. A harmonised entry is binding across the Union — an importer may not soften it, and a self-classification that diverges from it will not survive an enforcement check.
How is bromadiolone (ISO) classified for road, sea and air transport?
Carriers and forwarders handling bromadiolone compare section 14 against the shipping papers before loading. Any disagreement stops the consignment at the point where correcting it is most expensive.
Where is regulatory status recorded for bromadiolone (ISO)?
Regulatory status for bromadiolone changes independently of its hazard classification. A substance can keep the same hazard profile for years and acquire new obligations in section 15, which is why that section dates faster than section 2.
Which GHS pictograms apply to bromadiolone (ISO)?
The label for bromadiolone carries GHS06 (skull and crossbones), GHS08 (health hazard), GHS09 (environment), with the signal word Danger. These are not chosen by the supplier: CLP Annex VI states them for CAS 28772-56-7, and the precedence rules in Annex I decide which pictogram is dropped when two would say the same thing. A label showing a different set from the register is wrong even if every hazard statement on it is correct.
How do I check if my SDS for bromadiolone (ISO) is still valid?
An existing sheet for bromadiolone (ISO) may be reviewed against the register without obligation. The desirable outcome includes identifying discrepancies between sections, understanding the register’s specified requirements, and determining if such differences would prevent shipment authorisation.
What must the label for bromadiolone (ISO) contain?
The supply label for bromadiolone (ISO) is generated from the same classification that drives the safety data sheet: pictograms selected by precedence, one signal word derived from the highest hazard class present, and the hazard statements H360D, H330, H310… reproduced in full. Where the container is too small to carry the complete set at a legible size, there are lawful ways to handle it and unlawful ones that look identical to a non-specialist.
First-aid content and why it is read first
First-aid content for CAS 28772-56-7 has to be actionable by a person who is not a chemist and is reading under pressure. Section 4 also carries notes for the attending physician, which is where the classification becomes clinically relevant.
Which SDS sections decide whether a shipment clears?
The sixteen sections outlined in Annex II are not merely a formatting requirement; each section has a specific purpose, and inspectors review them by number. For the CAS registry number 28772-56-7, the sections typically determining acceptance are 2 (classification against the harmonised entry), 3 (composition and identifiers), 14 (transport) and 15 (regulatory status). It is imperative not to merge, renumber or omit any sections, as placeholders must remain unchanged.
In which language must the SDS for bromadiolone (ISO) be supplied?
A safety data sheet must be supplied in an official language of every Member State where bromadiolone (ISO) is placed on the market, unless that State has stated otherwise. This is the requirement most often missed by importers who hold a technically correct English document and assume it travels. A sheet in the wrong language is a refusal ground on its own, independent of the accuracy of its content.
Questions about documentation for bromadiolone
What is the CAS number of bromadiolone?
CAS 28772-56-7. In CLP Annex VI the same substance carries index number 607-[CAS?], and both identifiers should appear in the documentation.
Is bromadiolone a CMR substance?
Yes. The harmonised classification places it among substances classified as carcinogenic, mutagenic or toxic for reproduction, which changes workplace documentation and supply restrictions.
What hazard statements apply to CAS 28772-56-7?
The harmonised entry lists H360D, H330, H310, H300. These are binding across the Union and may not be softened by a self-classification.
In which language must the sheet be supplied?
In an official language of each Member State where bromadiolone is placed on the market, unless that State has stated otherwise.
MolGod.org issues documentation and does not sell, supply or ship chemical substances. CAS 28772-56-7 identifies the subject of this document.
Bibliografia (rozszerzona) (5)
- ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Tarazona, Jose V.. 2024. "Bromadiolone." Encyclopedia of Toxicology: 273-277. https://doi.org/10.1016/b978-0-12-824315-2.00716-8. link [dostep: 2026-08-25] CC0 (metadata)
- ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Ramasahayam, S.. 2014. "Bromadiolone." Encyclopedia of Toxicology: 549-551. https://doi.org/10.1016/b978-0-12-386454-3.00367-5. link [dostep: 2026-08-25] CC0 (metadata)
- ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Rao, K.S.. 2005. "Bromadiolone." Encyclopedia of Toxicology: 338-340. https://doi.org/10.1016/b0-12-369400-0/00150-2. link [dostep: 2026-08-25] CC0 (metadata)
- ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Deepa, Subbiah, Mishra, Ashok K.. 2005. "Fluorescence spectroscopic study of serum albumin–bromadiolone interaction: fluorimetric determination of bromadiolone." Journal of Pharmaceutical and Biomedical Analysis 38 (3): 556-563. https://doi.org/10.1016/j.jpba.2005.01.023. link [dostep: 2026-08-25] CC0 (metadata)
- ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Unger, Thomas A.. 1996. "Bromadiolone." Pesticide Synthesis Handbook: 845. https://doi.org/10.1016/b978-081551401-5.50653-5. link [dostep: 2026-08-25] CC0 (metadata)




