4,4′-diaminodiphenylmethane (CAS 101-77-9) — Safety Data Sheet

This page describes the regulatory documentation issued for 4,4′-diaminodiphenylmethane (CAS 101-77-9). The item supplied is a document, not the substance.

4,4′-diaminodiphenylmethane (CAS 101-77-9) at a glance

• Substance – 4,4′-diaminodiphenylmethane
• CAS number – 101-77-9
• EC number – 202-974-4
• CLP Annex VI index number – 612-[CAS?]
• Also known as – 4,4′-methylenedianiline
• Hazard statements – H350 (may cause cancer); H341 (suspected of causing genetic defects); H370 (causes damage to organs); H373 (may cause damage to organs through prolonged or repeated exposure); H317 (may cause an allergic skin reaction); H411 (toxic to aquatic life with long lasting effects)
• Hazard classes – Carc. 1B, Muta. 2, STOT SE 1, STOT RE 2 *, Skin Sens. 1, Aquatic Chronic 2
• Label pictograms – GHS07, GHS08, GHS09
• Signal word – Danger
• Entry current as of – CLP00
• CMR classification – yes, classified as carcinogenic, mutagenic or toxic for reproduction
• Documentation issued – safety data sheet in REACH Annex II structure; working draft or signed card
• What is supplied – a document. MolGod.org does not sell, supply or ship chemical substances.

Other names for this substance

The same substance appears in trade and in the literature under several names: 4,4′-methylenedianiline. A safety data sheet has to carry the name used in the harmonised entry, but a purchase order, a customs declaration and a certificate of analysis may each use a different one. Where the names diverge, CAS 101-77-9 is the identifier that reconciles them — and a document set that relies on trade names alone will eventually be read as describing three different materials.

What must the label for 4,4′-diaminodiphenylmethane contain?

The supply label for 4,4′-diaminodiphenylmethane is generated from the same classification that drives the safety data sheet: pictograms selected by precedence, one signal word derived from the highest hazard class present, and the hazard statements H350, H341, H370… reproduced in full. Where the container is too small to carry the complete set at a legible size, there are lawful ways to handle it and unlawful ones that look identical to a non-specialist.

Stability, reactivity and incompatibilities

The reactivity information for CAS 101-77-9 provided under Section 10 must be sufficiently detailed and actionable. While stating ‘avoid strong oxidizing agents’ offers a general category, specifying the exact chemical classes that react with the substance in question provides clearer guidance on appropriate handling and precautionary measures.

How do I check if my SDS for 4,4′-diaminodiphenylmethane is still valid?

Before ordering documentation for 4,4′-diaminodiphenylmethane, verify if the existing sheet can withstand an inspection. Conduct a section-by-section review against Annex II to determine compliance in one pass; if it meets the requirements, the honest assessment confirms its validity.

Is 4,4′-diaminodiphenylmethane on the SVHC candidate list?

Yes — 4,4′-diaminodiphenylmethane appears on the candidate list of substances of very high concern. That triggers duties that classification alone does not: notification to ECHA above the tonnage threshold, and an obligation to inform recipients where the substance is present in an article above 0.1 % by weight. It is also listed in Annex XIV, with a sunset date of 2014-08-21. Once a substance reaches Annex XIV, continued use in the Union requires an authorisation granted for a named use — a supplier relationship alone is not a legal basis.

How is 4,4′-diaminodiphenylmethane classified for road, sea and air transport?

Carriers and forwarders handling 4,4′-diaminodiphenylmethane compare section 14 against the shipping papers before loading. Any disagreement stops the consignment at the point where correcting it is most expensive.

Storage and handling in the document

Storage requirements for 4,4′-diaminodiphenylmethane must be addressed in Section 7 and should align with Section 10, which outlines prohibited conditions and materials. If discrepancies arise between the two sections, the documentation is considered internally inconsistent, and a laboratory auditor will deem both sections unreliable.

Can I import 4,4′-diaminodiphenylmethane into the EU?

An import of CAS 101-77-9 succeeds or fails on whether the accompanying sheet matches the register. Among amines and nitrogen bases the recurring failure is a classification carried over from a supplier outside the Union, where the same substance may be classified differently. Index 612-[CAS?] is the binding reference, and it is in intermediate and reagent shipments that the discrepancy surfaces.

What is the EC number for 4,4′-diaminodiphenylmethane?

Alongside CAS 101-77-9, this substance carries EC number 202-974-4 and Annex VI index 612-[CAS?]. European documentation is built around the EC number as often as around the CAS: registration dossiers, the candidate list and customs systems key on it. A safety data sheet quoting only one of the two forces every downstream reader to look up the other.

Identifiers that must agree

Identity is checked before hazard. If the label, the sheet and the certificate disagree about what CAS 101-77-9 is called, or if index 612-[CAS?] points somewhere the name does not, a reviewer stops trusting all three documents at once, even though each was internally consistent.

Purity, certificates and what the sheet does not say

The purity grade is determined by a certificate of analysis rather than a safety data sheet. The safety data sheet for 4,4′-diaminodiphenylmethane provides information about the substance itself, while a certificate of analysis specifically details a particular batch, including measured results against the specification and the analytical method used for each parameter. Laboratories typically request both documents when they refer to ‘the COA’.

Protective equipment and exposure controls

Section 8 details exposure controls and personal protective equipment (PPE) for 4,4′-diaminodiphenylmethane: appropriate glove materials, eye protection, respiratory protection when required by the hazard classification, and any established occupational exposure limits. The selection of glove material is more important than merely wearing gloves; nitrile gloves are not universally suitable.

Disposal route and waste classification

Section 13 for CAS 101-77-9 states the disposal route and any contaminated-packaging handling. Laboratories are audited on whether their waste stream matches what the sheet declares, so a vague section here becomes a finding on the laboratory rather than on the supplier.

Is 4,4′-diaminodiphenylmethane classified as a CMR substance?

CAS 101-77-9 is classified as a CMR substance (H350). That status changes the obligations attached to every shipment: workplace exposure documentation, restrictions on supply to the general public, and substitution pressure from downstream users who must justify continued use. A safety data sheet for a CMR substance is read more closely than any other, because the classification itself invites scrutiny.

What is the CLP classification of 4,4′-diaminodiphenylmethane?

The harmonised classification for CAS 101-77-9 carries 6 hazard statements: H350, H341, H370, H373, H317, H411. In plain terms this means may cause cancer; suspected of causing genetic defects; causes damage to organs; may cause damage to organs through prolonged or repeated exposure. A harmonised entry is binding across the Union — an importer may not soften it, and a self-classification that diverges from it will not survive an enforcement check.

Why a correct sheet stops being correct

Classification under CLP moves with each Adaptation to Technical Progress. A sheet for CAS 101-77-9 written before the amendment that touched its entry keeps stating a classification the register no longer holds. Nothing in the document announces this — it reads exactly as it did on the day it was issued, which is precisely why revision dates are checked before content.

In which language must the SDS for 4,4′-diaminodiphenylmethane be supplied?

Language compliance is mandatory rather than optional. When 4,4′-diaminodiphenylmethane is delivered to a customer, the receiving Member State may mandate the use of its official language, and several do so without exception. An English original that meets an auditor’s requirements in one country can be rejected at the subsequent border, with no alteration to the content but due solely to the choice of language.

Which GHS pictograms apply to 4,4′-diaminodiphenylmethane?

The label for 4,4′-diaminodiphenylmethane carries GHS07 (exclamation mark), GHS08 (health hazard), GHS09 (environment), with the signal word Danger. These are not chosen by the supplier: CLP Annex VI states them for CAS 101-77-9, and the precedence rules in Annex I decide which pictogram is dropped when two would say the same thing. A label showing a different set from the register is wrong even if every hazard statement on it is correct.

Questions about documentation for 4,4′-diaminodiphenylmethane

What is the CAS number of 4,4′-diaminodiphenylmethane?

CAS 101-77-9. In CLP Annex VI the same substance carries index number 612-[CAS?], and both identifiers should appear in the documentation.

Is 4,4′-diaminodiphenylmethane a CMR substance?

Yes. The harmonised classification places it among substances classified as carcinogenic, mutagenic or toxic for reproduction, which changes workplace documentation and supply restrictions.

What hazard statements apply to CAS 101-77-9?

The harmonised entry lists H350, H341, H370, H373. These are binding across the Union and may not be softened by a self-classification.

In which language must the sheet be supplied?

In an official language of each Member State where 4,4′-diaminodiphenylmethane is placed on the market, unless that State has stated otherwise.

MolGod.org issues documentation and does not sell, supply or ship chemical substances. CAS 101-77-9 identifies the subject of this document.