2,3-epoxypropan-1-ol (CAS 556-52-5) — Safety Data Sheet

2,3-epoxypropan-1-ol — CAS 556-52-5, Annex VI index 603-[CAS?]. Below: what the regulatory file for this substance must contain and where such files usually fail.

2,3-epoxypropan-1-ol (CAS 556-52-5) at a glance

• Substance – 2,3-epoxypropan-1-ol
• CAS number – 556-52-5
• EC number – 209-128-3
• CLP Annex VI index number – 603-[CAS?]
• Also known as – glycidol, oxiranemethanol
• Hazard statements – H350 (may cause cancer); H341 (suspected of causing genetic defects); H360F (may damage fertility); H331 (toxic if inhaled); H312 (harmful in contact with skin); H302 (harmful if swallowed)
• Hazard classes – Carc. 1B, Muta. 2, Repr. 1B, Acute Tox. 3 *, Acute Tox. 4 *, Acute Tox. 4 *
• Label pictograms – GHS06, GHS08
• Signal word – Danger
• Entry current as of – CLP00
• CMR classification – yes, classified as carcinogenic, mutagenic or toxic for reproduction
• Documentation issued – safety data sheet in REACH Annex II structure; working draft or signed card
• What is supplied – a document. MolGod.org does not sell, supply or ship chemical substances.

In which language must the SDS for 2,3-epoxypropan-1-ol be supplied?

A safety data sheet must be supplied in an official language of every Member State where 2,3-epoxypropan-1-ol is placed on the market, unless that State has stated otherwise. This is the requirement most often missed by importers who hold a technically correct English document and assume it travels. A sheet in the wrong language is a refusal ground on its own, independent of the accuracy of its content.

What happens if a consignment of 2,3-epoxypropan-1-ol is refused?

Refusals involving 2,3-epoxypropan-1-ol cluster around three causes: a classification overtaken by an amendment, transport data contradicting the shipping papers, and a language the receiving authority does not accept. None of the three is visible to a reader satisfied that the document looks professional.

Is 2,3-epoxypropan-1-ol classified as a CMR substance?

CAS 556-52-5 is classified as a CMR substance (H350, H360F). That status changes the obligations attached to every shipment: workplace exposure documentation, restrictions on supply to the general public, and substitution pressure from downstream users who must justify continued use. A safety data sheet for a CMR substance is read more closely than any other, because the classification itself invites scrutiny.

Who is responsible for REACH compliance for 2,3-epoxypropan-1-ol?

Anyone importing 2,3-epoxypropan-1-ol into the European Union is responsible for providing the required documentation, and this obligation does not revert to previous entities in the supply chain through contractual means. Section 1 mandates the designation of a contactable entity within the Union; a foreign address is considered invalid for this purpose and is one of the first elements verified by inspectors due to its straightforward confirmation.

Stability, reactivity and incompatibilities

Incompatibilities for 2,3-epoxypropan-1-ol belong in section 10 and must not contradict the storage guidance in section 7. Where a sheet lists a material as incompatible in one section and acceptable in another, the document has stopped being usable.

Where is regulatory status recorded for 2,3-epoxypropan-1-ol?

Section 15 records regulatory status for 2,3-epoxypropan-1-ol: whether it appears on the candidate list, whether it is subject to authorisation or restriction, and any national provisions. Downstream users ask this question routinely, and a sheet that answers it saves an exchange of emails per customer.

Disposal route and waste classification

Section 13 for CAS 556-52-5 states the disposal route and any contaminated-packaging handling. Laboratories are audited on whether their waste stream matches what the sheet declares, so a vague section here becomes a finding on the laboratory rather than on the supplier.

What must the label for 2,3-epoxypropan-1-ol contain?

The supply label for 2,3-epoxypropan-1-ol is generated from the same classification that drives the safety data sheet: pictograms selected by precedence, one signal word derived from the highest hazard class present, and the hazard statements H350, H341, H360F… reproduced in full. Where the container is too small to carry the complete set at a legible size, there are lawful ways to handle it and unlawful ones that look identical to a non-specialist.

What is the CLP classification of 2,3-epoxypropan-1-ol?

The harmonised classification for CAS 556-52-5 carries 9 hazard statements: H350, H341, H360F, H331, H312, H302, H335, H315, H319. In plain terms this means may cause cancer; suspected of causing genetic defects; may damage fertility; toxic if inhaled. A harmonised entry is binding across the Union — an importer may not soften it, and a self-classification that diverges from it will not survive an enforcement check.

Can I import 2,3-epoxypropan-1-ol into the EU?

Introducing 2,3-epoxypropan-1-ol into the Union requires documentation to be prepared prior to logistics arrangements. The documentation file must already be available at the time of import, not merely upon request; for this purpose, alcohols and ethers is evaluated within the context of solvent shipments. Index 603-[CAS?] establishes the classification that Section 2 must mirror accordingly.

How is 2,3-epoxypropan-1-ol classified for road, sea and air transport?

The transport classification for 2,3-epoxypropan-1-ol falls under section 14 and varies depending on the mode of transport: ADR for road, IMDG for sea, and IATA for air. A document that prints all three classifications without specifying which one applies places the responsibility on the shipper to select the correct one, and it is the shipper who faces penalties for making an incorrect choice.

Which GHS pictograms apply to 2,3-epoxypropan-1-ol?

The label for 2,3-epoxypropan-1-ol carries GHS06 (skull and crossbones), GHS08 (health hazard), with the signal word Danger. These are not chosen by the supplier: CLP Annex VI states them for CAS 556-52-5, and the precedence rules in Annex I decide which pictogram is dropped when two would say the same thing. A label showing a different set from the register is wrong even if every hazard statement on it is correct.

Identifiers that must agree

Identity verification must be conducted prior to hazard assessment. If discrepancies exist between the label, safety data sheet, and certificate regarding the CAS 556-52-5 number or if the index 603-[CAS?] refers to a location where the name does not match, a reviewer will lose trust in all three documents simultaneously, despite their internal consistency. This is because inconsistencies among these key documentation elements undermine their reliability as a unified source of information.

Documentation demand on the EU market

CAS 556-52-5 has a recorded presence on the European trading market, which means documentation for it is requested routinely rather than exceptionally. Substances that move in commerce attract repeat scrutiny: the same sheet is read by successive customers, carriers and authorities, and a defect that survives the first reading rarely survives the tenth.

Accidental release and containment

Emergency procedures for 2,3-epoxypropan-1-ol are read at the moment of the incident, so section 6 is written for speed: what to evacuate, what to contain with, and what must not be used.

What is the EC number for 2,3-epoxypropan-1-ol?

Alongside CAS 556-52-5, this substance carries EC number 209-128-3 and Annex VI index 603-[CAS?]. European documentation is built around the EC number as often as around the CAS: registration dossiers, the candidate list and customs systems key on it. A safety data sheet quoting only one of the two forces every downstream reader to look up the other.

Why a correct sheet stops being correct

Classification under CLP moves with each Adaptation to Technical Progress. A sheet for CAS 556-52-5 written before the amendment that touched its entry keeps stating a classification the register no longer holds. Nothing in the document announces this — it reads exactly as it did on the day it was issued, which is precisely why revision dates are checked before content.

Which SDS sections decide whether a shipment clears?

The sheet for CAS 556-52-5 must be read numerically rather than narratively; subsections carry the same weight as sections: an inspector seeking information under point 3.1 will not accept data presented within a paragraph elsewhere, regardless of that paragraph’s completeness. Completeness is initially assessed by structure, followed by content evaluation.

Questions about documentation for 2,3-epoxypropan-1-ol

Do I need a safety data sheet to import 2,3-epoxypropan-1-ol into the EU?

Yes. A sheet compiled to Annex II of REACH must exist before the first consignment moves, and it must be held by the entity placing the substance on the Union market.

What is the CAS number of 2,3-epoxypropan-1-ol?

CAS 556-52-5. In CLP Annex VI the same substance carries index number 603-[CAS?], and both identifiers should appear in the documentation.

Is 2,3-epoxypropan-1-ol a CMR substance?

Yes. The harmonised classification places it among substances classified as carcinogenic, mutagenic or toxic for reproduction, which changes workplace documentation and supply restrictions.

What hazard statements apply to CAS 556-52-5?

The harmonised entry lists H350, H341, H360F, H331. These are binding across the Union and may not be softened by a self-classification.

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