4-Methyl-5-(2-hydroxyethyl)thiazole

CAS 137-00-8 · C₆H₉NOS · MW 143.21 g/mol

Full record: 4-Methyl-5-(2-hydroxyethyl)thiazole — Safety Data Sheet →

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4-Methyl-5-(2-hydroxyethyl)thiazole (CAS 137-00-8), C6H9NOS - 3D ball-and-stick molecular model, engraved element symbols (C H N O S), MolGod STL preview

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Download 3D model: 4-Methyl-5-(2-hydroxyethyl)thiazole, C₆H₉NOS, CAS 137-00-8 · ENGRAVED (C, H, N, O, S) · 11 MB

4-Methyl-5-(2-hydroxyethyl)thiazole (CAS 137-00-8), C6H9NOS - 3D ball-and-stick molecular model, MolGod STL preview

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About 4-Methyl-5-(2-hydroxyethyl)thiazole

4-Methyl-5-(2-hydroxyethyl)thiazole is a chemical compound registered under number CAS 137-00-8, with the molecular formula C₆H₉NOS, and a molar mass of 143.21 g/mol.

The molecule contains 18 atoms connected by 18 chemical bonds. The full systematic IUPAC name of this compound is 2-(4-methyl-1,3-thiazol-5-yl)ethanol. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = 0.8 (positive value, a lipophilic compound), polar surface area PSA = 61.4 Å², 1 donors and 3 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The interactive 3D model and the viewer images are protected by copyright (© MolGod.org) — terms of use: molgod.org/copyright/.

Physicochemical properties

Molecular formula	C₆H₉NOS
Molar mass	143.21 g/mol
IUPAC	2-(4-methyl-1,3-thiazol-5-yl)ethanol
SMILES	`CC1=C(SC=N1)CCO`
InChIKey	`BKAWJIRCKVUVED-UHFFFAOYSA-N`
logP (XLogP3)	0.8
PSA	61.4 Å²
HBD / HBA	1 / 3
PubChem CID	CID 1136 ↗

GHS safety

Signal word: Warning

GHS07

GHS07

H315 — Causes skin irritation

H319 — Causes serious eye irritation

H335 — May cause respiratory irritation

Scientific literature

Related literature

2 articles · 1 open access · Sources: PubMed, OpenAlex, Semantic Scholar

📈 Publication timeline (number of articles: 2)

Bar height = number of articles in a given year. Hover over a bar to see details.

🔓

RIFM fragrance ingredient safety assessment, 4-methyl-5-thiazoleethanol, CAS Registry Number 137-00-8.

Api AM, Belsito D, Botelho D et al. (2020) · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Cytowania: 3ReviewOpen AccessDOI ↗PubMed ↗PDF ↗

Transport of thiamine and 4-methyl-5-hydroxyethylthiazole by Salmonella typhimurium.

Bellion E, Lash TD, McKellar BR (1983) · Biochimica et biophysica acta

$ PaywallDOI ↗PubMed ↗

Data from PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary generated by Semantic Scholar TLDR. Articles marked with require paid access.

Synonyms

4-METHYL-5-THIAZOLEETHANOL · 137-00-8 · 5-(2-Hydroxyethyl)-4-methylthiazole · Hemineurine · 5-Thiazoleethanol, 4-methyl- · 2-(4-Methyl-1,3-thiazol-5-yl)ethanol · 4-Methyl-5-thiazolethanol · 4-Methyl-5-(2-hydroxyethyl)thiazole · 4-Methyl-5-thiazolylethanol · 2-(4-Methylthiazole-5-yl)ethanol · 4-Methyl-5-hydroxyethylthiazole · 4-Methyl-5-hydroxethylthiazole · 2-(4-Methyl-1,3-Thiazol-5-Yl)Ethan-1-Ol · FEMA No. 3204 · 5-(beta-Hydroxyethyl)-4-methylthiazole

Data sources

📊 PubChem CID 1136 — NIH
🔬 NIST WebBook — spectroscopy
💊 ChEMBL — bioactivity

📜 License & provenanceMolGod_License_1

COMPUTED — PubChem3D · 3D conformer computed by PubChem using OMEGA; not an experimental structure.

Model: 4-Methyl-5-(2-hydroxyethyl)thiazole · 137-00-8
InChIKey: BKAWJIRCKVUVED-UHFFFAOYSA-N
License: CC BY-SA 4.0 International
Attribution: MolGod Scientific — 4-Methyl-5-(2-hydroxyethyl)thiazole (CAS 137-00-8)
License & provenance record: 4-Methyl-5-(2-hydroxyethyl)thiazole (CAS 137-00-8) →
MolGod molecule record: 4-Methyl-5-(2-hydroxyethyl)thiazole →
Source data: PubChem CID 1136 ↗
Model information: STL generated by MolGod · MolGod STL Exporter build 48804cd20b0d · generated 2026-10-14
SHA-256 (STL): 57f2a9867731079295e3c3e6123409a090f8dbb1b34437531546d54a891ac356
MD5 (STL): 0f956fc628af7e2f8c0f26d6cfd77e3d
MolGod Identification Number: MG_295-018-015-49
Transformation: MolGod Scientific ball-and-stick mesh
Changes: Converted into a triangulated molecular mesh; atomic coordinates and connectivity unchanged.
Wikimedia Commons: not published yet

📄 Download 3D model: 4-Methyl-5-(2-hydroxyethyl)thiazole, C₆H₉NOS, CAS 137-00-8 · NORMAL · 375 KB 📄 Download 3D model: 4-Methyl-5-(2-hydroxyethyl)thiazole, C₆H₉NOS, CAS 137-00-8 · ENGRAVED (C, H, N, O, S) · 11 MB

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