Tetramethoxypropane

Name: Tetramethoxypropane (CAS 102-52-3) — complete chemical dataset
Creator: MolGod.org
License: https://molgod.org/copyright/#data

CAS 102-52-3 · C₇H₁₆O₄ · MW 164.20 g/mol

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About Tetramethoxypropane

Tetramethoxypropane is a chemical compound registered under number CAS 102-52-3, with the molecular formula C₇H₁₆O₄, and a molar mass of 164.20 g/mol.

The molecule contains 27 atoms connected by 26 chemical bonds. The full systematic IUPAC name of this compound is 1,1,3,3-tetramethoxypropane. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = 0.3 (positive value, a lipophilic compound), polar surface area PSA = 36.9 Å², 0 donors and 4 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The interactive 3D model and the viewer images are protected by copyright (© MolGod.org) — terms of use: molgod.org/copyright/.

Physicochemical properties

Molecular formula	C₇H₁₆O₄
Molar mass	164.20 g/mol
IUPAC	1,1,3,3-tetramethoxypropane
SMILES	`COC(CC(OC)OC)OC`
InChIKey	`XHTYQFMRBQUCPX-UHFFFAOYSA-N`
logP (XLogP3)	0.3
PSA	36.9 Å²
HBD / HBA	0 / 4
PubChem CID	CID 66019 ↗

GHS safety

Signal word: Warning

GHS02

H226 — Flammable liquid and vapour

Scientific literature

Related literature

19 articles · 3 open access · Sources: PubMed, OpenAlex, Semantic Scholar

📈 Publication timeline (number of articles: 19)

Bar height = number of articles in a given year. Hover over a bar to see details.

Efficient synthesis of salicylates by catalytic [3 + 3] cyclizations of 1,3-bis(silyl enol ethers) with 1,1,3,3-tetramethoxypropane.

et al. (2007)

Cytowania: 4$ PaywallDOI ↗PubMed ↗

Synthesis of Nucleoside and Nucleotide Analogues by Cyclization of the Guanine Base with 1,1,3,3-Tetramethoxypropane.

et al. (2022)

Cytowania: 5$ PaywallDOI ↗PubMed ↗

Fluorescent malondialdehyde polymers from hydrolysed 1,1,3,3-tetramethoxypropane

J.M.C. Gutteridge, A.D. Heys, J. Lunec (1977) · Analytica Chimica Acta

Cytowania: 22$ PaywallDOI ↗

Stereoselective Transacetalization of 1,1,3,3-Tetramethoxypropane andN-Benzoylaminodiols

Lanrong Bi, Ming Zhao, Chao Wang et al. (2000) · European Journal of Organic Chemistry

Cytowania: 14$ PaywallDOI ↗

🔓

Hydrolysis of 1,1,3,3-tetramethoxypropane and spectrophotometric determination of its product, malondialdehyde.

Hiromu IMAI, Zenichi ARAI (1991) · BUNSEKI KAGAKU

Cytowania: 4Open AccessDOI ↗PDF ↗

Condensation of ferrocene with 1,1,3,3-tetramethoxypropane

Paula Dudnik, Jean M. Tancrede, M. Rosenblum (1969) · Journal of Organometallic Chemistry

Cytowania: 9$ PaywallDOI ↗

Acid-Promoted Cyclization Reaction of the Guanine Base with 1,1,3,3-Tetramethoxypropane: A Method for the Preparation of M<sub>1</sub> dG and its Derivatives.

et al. (2023)

Cytowania: 1$ PaywallDOI ↗PubMed ↗

🔓

3-Hydroxy-2,2-bis(1H-pyrazol-1-yl)cyclopentanone

Marina A. Yurovskaya, Alexander V. Kurkin, Victor B. Rybakov et al. (2012) · Acta Crystallographica Section E

Cytowania: 1Open AccessDOI ↗PDF ↗

Regioselective Synthesis of 2-(Arylthio)benzoates by the First Catalytic [3+3] Cyclocondensations of 3-(Arylthio)-1-(trimethylsilyloxy)-1,3-butadienes with 1,1,3,3-Tetramethoxypropane

Muhammad Imran, Inam Iqbal, Nasir Rasool et al. (2008) · Synlett

$ PaywallDOI ↗

Infrared and ultraviolet-visible spectroscopic studies of plasma polymerized 1, 1, 3, 3 - tetramethoxypropane thin films

Tamanna Afroze, A.H. Bhuiyan (2011) · Thin Solid Films

Cytowania: 19$ PaywallDOI ↗

Alternating Current Electrical Properties of Thin Films of Plasma Polymerized 1, 1, 3, 3‐Tetramethoxypropane

Tamanna Afroze, A. H. Bhuiyan (2013) · Advances in Polymer Technology

Cytowania: 8$ PaywallDOI ↗

Effect of Aging on the Optical Properties of Plasma Polymerized 1,1,3,3‐Tetramethoxypropane Thin Films

Tamanna Afroze, A. H. Bhuiyan (2013) · Advances in Polymer Technology

Cytowania: 5$ PaywallDOI ↗

Synthesis of Nucleoside and Nucleotide Analogues by Cyclization of the Guanine Base with 1,1,3,3-Tetramethoxypropane

$ PaywallDOI ↗

Efficient Synthesis of Salicylates by Catalytic [3 + 3] Cyclizations of 1,3-Bis(silyl enol ethers) with 1,1,3,3-Tetramethoxypropane

$ PaywallDOI ↗

🔓

Efficient Synthesis of Salicylates by Catalytic [3 + 3] Cyclizations of 1,3‐Bis(silyl enol ethers) with 1,1,3,3‐Tetramethoxypropane.

Muhammad Sher, T. H. Tam Dang, Zafar Ahmed et al. (2007) · ChemInform

Open AccessDOI ↗PDF ↗

1,1,3,3‐tetramethoxypropane

(2007) · Hawley's Condensed Chemical Dictionary

$ PaywallDOI ↗

1,1,1,3-Tetramethoxypropane

Stanley Raucher (2001) · Encyclopedia of Reagents for Organic Synthesis

$ PaywallDOI ↗

ChemInform Abstract: Stereoselective Transacetalization of 1,1,3,3‐Tetramethoxypropane and N‐Benzoylaminodiols.

Lanrong Bi, Ming Zhao, Chao Wang et al. (2001) · ChemInform

$ PaywallDOI ↗

ChemInform Abstract: Condensation of 1‐Methylphthalazinium Perchlorates with Triethyl Orthoformate and 1,1,3,3‐Tetramethoxypropane. Synthesis of Carbocyanines from Phthalazinium Salts.

I. G. OVCHINNIKOVA, I. V. SAMARTSEVA, L. A. PAVLOVA (1990) · ChemInform

$ PaywallDOI ↗

Data from PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary generated by Semantic Scholar TLDR. Articles marked with require paid access.

Synonyms

1,1,3,3-Tetramethoxypropane · 102-52-3 · Propane, 1,1,3,3-tetramethoxy- · Tetramethoxypropane · Malonaldehyde tetramethyl acetal · Malonaldehyde, bis(dimethyl acetal) · GUB3D2SV2S · NSC-27794 · RefChem:70935 · DTXCID7032684 · 1,1,3,3-TMP · 203-037-2 · Malonaldehyde bis(dimethyl acetal) · MFCD00008488 · 1,1,3,3-tetrakis(methyloxy)propane

Data sources

📊 PubChem CID 66019 — NIH
🔬 NIST WebBook — spectroscopy
💊 ChEMBL — bioactivity

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COMPUTED — PubChem3D · 3D conformer computed by PubChem using OMEGA; not an experimental structure.

ENGRAVEDNORMAL

Tetramethoxypropane (CAS 102-52-3), C7H16O4 - 3D ball-and-stick molecular model, engraved element symbols (C H O), MolGod STL preview

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Tetramethoxypropane (CAS 102-52-3), C7H16O4 - 3D ball-and-stick molecular model, MolGod STL preview

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Model: Tetramethoxypropane · 102-52-3
InChIKey: XHTYQFMRBQUCPX-UHFFFAOYSA-N
License: CC BY-SA 4.0 International
Attribution: MolGod Scientific — Tetramethoxypropane (CAS 102-52-3)
License & provenance record: Tetramethoxypropane (CAS 102-52-3) →
MolGod molecule record: Tetramethoxypropane →
Source data: PubChem CID 66019 ↗
Model information: STL generated by MolGod · MolGod STL Exporter build 48804cd20b0d · generated 2026-10-14
SHA-256 (STL): fa249cb0bcd193b5498e93f4e90cde8fde888208b0c2ceb39e4eec3e7034f04d
MD5 (STL): c976ce0821e38f94baa4e8f9b0945ae8
MolGod Identification Number: MG_364-436-300-23
Transformation: MolGod Scientific ball-and-stick mesh
Changes: Converted into a triangulated molecular mesh; atomic coordinates and connectivity unchanged.
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