Tetrahydrofuran (THF) (CAS 96-49-1)

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Tetrahydrofuran (THF) | High. CAS 96-49-1.

⚠️ Note: This safety data sheet is provided in English; a localized version is being prepared.

Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.

REACH 2020/878
v1 · 02.09.2026
Download Safety Data Sheet (PDF)CAS 96-49-1 · PDF · 160 KBWorking draft — not yet reviewed and approved.

Section 9 — physicochemical properties: 8 of 22 established.

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Przegląd chemiczny: Ethylene carbonate
Wzór sumarycznyC3H4O3[1]
Masa cząsteczkowa88.06 g/mol[1]
LogP (lipofilowość)0.3[1]
Nazwa IUPAC1,3-dioxolan-2-one[1]
SMILESC1COC(=O)O1[1]
InChIKeyKMTRUDSVKNLOMY-UHFFFAOYSA-N[1]

Synonimy: Ethylene carbonate · 1,3-DIOXOLAN-2-ONE · 96-49-1 · Glycol carbonate · Ethylene glycol carbonate

Data sources: PubChem (NLM/NIH)
Last updated: 2026-09-02

📚 Naukowe referencje (Chicago Author-Date) (1 źródeł)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: Wzór sumaryczny · Masa cząsteczkowa · LogP (lipofilowość) · Nazwa IUPAC · SMILES · InChIKey

BADANIA NAUKOWE

[1]PubMed2025
Berthod A, Armstrong DW. (2025). "On the use of ethylene carbonate as a green solvent in mobile phases.". Journal of chromatography. A. https://doi.org/10.1016/j.chroma.2025.466259
[2]PubMed2024
Teherpuria H, Yadav H, Mohapatra S et al.. (2024). "Pectin alignment induced changes in ion solvation structure in ethylene carbonate-based liquid electrolytes.". International journal of biological m
[3]PubMed2022
Eilmes A, Kubisiak P, Wróbel P. (2022). "Explicit and Hybrid Solvent Models for Estimates of Parameters Relevant to the Reduction Potential of Ethylene Carbonate.". International journal of molecular
[4]PubMed2022
Wang Z, Yu K, Zhao Y et al.. (2022). "Aggregation induced spectral splitting and Fermi resonance of Ethylene Carbonate in binary mixture.". Spectrochimica acta. Part A, Molecular and biomolecular spec
[5]PubMed2020
Bohr A, Nascimento TL, Harmankaya N et al.. (2020). "Antioxidant-mediated control of degradation and drug release from surface-eroding poly(ethylene carbonate).". Acta biomaterialia. https://doi.org/1
[6]PubMed2020
von Seggern N, Schindler T, Naumann S. (2020). "Dual Catalytic Ring-Opening Polymerization of Ethylene Carbonate for the Preparation of Degradable PEG.". Biomacromolecules. https://doi.org/10.1021/acs
[7]PubMed2018
Chaudhari MI, Muralidharan A, Pratt LR et al.. (2018). "Assessment of Simple Models for Molecular Simulation of Ethylene Carbonate and Propylene Carbonate as Solvents for Electrolyte Solutions.". Topi
[8]PubMed1998
Yang YL, Ramaswamy SG, Jakoby WB. (1998). "Enzymatic hydrolysis of organic cyclic carbonates.". The Journal of biological chemistry. https://doi.org/10.1074/jbc.273.14.7814
📚 Naukowe referencje (Chicago Author-Date) 9 refs · 1 baz

MOLECULE Bibliografia per-CAS (live z 13+ baz)

Źródła: db:pubmed (9)

  1. db:pubmed Berthod A, Armstrong DW. (2025). "On the use of ethylene carbonate as a green solvent in mobile phases.". Journal of chromatography. A. https://doi.org/10.1016/j.chroma.2025.466259
  2. db:pubmed Teherpuria H, Yadav H, Mohapatra S et al.. (2024). "Pectin alignment induced changes in ion solvation structure in ethylene carbonate-based liquid electrolytes.". International journal of biological macromolecules. https://doi.org/10.1016/j.ijbiomac.2024.137395
  3. db:pubmed Eilmes A, Kubisiak P, Wróbel P. (2022). "Explicit and Hybrid Solvent Models for Estimates of Parameters Relevant to the Reduction Potential of Ethylene Carbonate.". International journal of molecular sciences. https://doi.org/10.3390/ijms232415590
  4. db:pubmed Wang Z, Yu K, Zhao Y et al.. (2022). "Aggregation induced spectral splitting and Fermi resonance of Ethylene Carbonate in binary mixture.". Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. https://doi.org/10.1016/j.saa.2022.121593
  5. db:pubmed Bohr A, Nascimento TL, Harmankaya N et al.. (2020). "Antioxidant-mediated control of degradation and drug release from surface-eroding poly(ethylene carbonate).". Acta biomaterialia. https://doi.org/10.1016/j.actbio.2020.06.041
  6. db:pubmed von Seggern N, Schindler T, Naumann S. (2020). "Dual Catalytic Ring-Opening Polymerization of Ethylene Carbonate for the Preparation of Degradable PEG.". Biomacromolecules. https://doi.org/10.1021/acs.biomac.0c00360
  7. db:pubmed Chaudhari MI, Muralidharan A, Pratt LR et al.. (2018). "Assessment of Simple Models for Molecular Simulation of Ethylene Carbonate and Propylene Carbonate as Solvents for Electrolyte Solutions.". Topics in current chemistry (Cham). https://doi.org/10.1007/s41061-018-0187-2
  8. db:pubmed Yang YL, Ramaswamy SG, Jakoby WB. (1998). "Enzymatic hydrolysis of organic cyclic carbonates.". The Journal of biological chemistry. https://doi.org/10.1074/jbc.273.14.7814
  9. db:pubmed Hanley TR Jr, Schumann AM, Langvardt PW et al.. (1989). "Metabolism and disposition of ethylene carbonate in male Fischer 344 rats.". Toxicology and applied pharmacology. https://doi.org/10.1016/0041-008x(89)90088-4
Status regulacyjny substancji
Ta substancja podlega wymogom regulacyjnym: gospodarka odpadami niebezpiecznymi (BDO). Szczegoly w sekcji "Status regulacyjny (REACH/ECHA/CLP)" oraz na karcie SDS. Informacja regulacyjna — nie ogranicza zakupu w sklepie.
🧪 Dane chemiczne
Numer CAS
96-49-1
Wzór sumaryczny
C3H4O3
Masa molowa
88.06 g/mol
Nazwa IUPAC (EN)
1,3-dioxolan-2-one
SMILES
C1COC(=O)O1
InChIKey
KMTRUDSVKNLOMY-UHFFFAOYSA-N
⚗️ Physicochemical properties
Temp. topnienia
36.9
Density
1.322

Source: PubChem, NIST WebBook. Last updated: 2026-09-02

🔍 Identyfikatory zewnętrzne
12 z 16 systemów ID75%
BazaIdentyfikatorAkcje
CAS Registry Number96-49-1Otwórz →
PubChem CID7303[1]Otwórz →
InChIKeyKMTRUDSVKNLOMY-UHFFFAOYSA-N[1]Otwórz →
InChIInChI=1S/C3H4O3/c4-3-5-1-2-6-3/h1-2H2[1]
SMILESC1COC(=O)O1[1]
EC Number202-510-0[2]Otwórz →
ChEMBLCHEMBL3181803[3]Otwórz →
HMDBHMDB0252067Otwórz →
ChemSpider7030[4]Otwórz →
UNII (FDA)RGJ96TB7R7Otwórz →
NSC Number (NCI)16568Otwórz →
WikiData QIDQ421145Otwórz →

Źródła: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Naukowe referencje (Chicago Author-Date) (4 źródeł)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · InChI · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChEMBL. European Bioinformatics Institute (EMBL-EBI), bioactivity database. dotyczy: ChEMBL
  4. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

Dalsza literatura

Publications topically related to this CAS. They are not the source of any value given on this card.

Bibliografia (rozszerzona) (5)

  1. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Esteban, Jesús, Ladero, Miguel, García-Ochoa, Félix. 2015. "Liquid–liquid equilibria for the systems ethylene carbonate + ethylene glycol + glycerol; ethylene carbonate + glycerol carbonate + glycerol and ethylene carbonate + ethylene glycol + glycerol carbonate + glycerol at catalytic reacting temperatures." Chemical Engineering Research and Design 94: 440-448. https://doi.org/10.1016/j.cherd.2014.08.024. link [dostep: 2026-09-03] CC0 (metadata)
  2. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Anonymous. "MeTFSI (Me = Li, Na) Solvation in Ethylene Carbonate and Fluorinated Ethylene Carbonate: A Molecular Dynamics Study.". https://doi.org/10.1021/acs.jpcb.0c10622.s001. link [dostep: 2026-09-03] CC0 (metadata)
  3. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Anonymous. "Not All Fluorination Is the Same: Unique Effects of Fluorine Functionalization of Ethylene Carbonate for Tuning Solid-Electrolyte Interphase in Li Metal Batteries.". https://doi.org/10.1021/acs.langmuir.0c01652.s001. link [dostep: 2026-09-03] CC0 (metadata)
  4. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Anonymous. "StructureProperty Relationships of Poly(ethylene carbonate) and Poly(propylene carbonate).". https://doi.org/10.1021/acsomega.7b00964.s001. link [dostep: 2026-09-03] CC0 (metadata)
  5. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Anonymous. "Dielectric Relaxation of Ethylene Carbonate and Propylene Carbonate from Molecular Dynamics Simulations.". https://doi.org/10.1021/acs.jpcb.5b09561.s001. link [dostep: 2026-09-03] CC0 (metadata)

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Tetrahydrofuran (THF) | High — CAS 96-49-1. Listed by Anhui Eapearl. Prepared from the supplier’s public catalogue; not verified against their internal data.

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