Pharmaceutical Grade L-Lysine Hydrochloride (CAS 657-27-2)

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Pharmaceutical Grade L-Lysine Hydrochloride. CAS 657-27-2.

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Données transcrites à partir de registres réglementaires et de la littérature spécialisée, avec indication de la source et de l'édition. Elles ne remplacent pas la fiche de données de sécurité du fournisseur. Les champs sans source enregistrée sont signalés comme tels.

Aperçu chimique: L-Lysine monohydrochloride
Formule bruteC₆H₁₅ClN₂O₂[1]
Masse moléculaire182.65 g/mol[1]
Nom IUPAC(2S)-2,6-diaminohexanoic acid;hydrochloride[1]
SMILESC(CCN)C[C@@H](C(=O)O)N.Cl[1]
InChIKeyBVHLGVCQOALMSV-JEDNCBNOSA-N[1]

Synonymes: L-Lysine hydrochloride · 657-27-2 · L-Lysine monohydrochloride · lysine hydrochloride · L-Lysine, monohydrochloride

Sources de données : PubChem (NLM/NIH)
Dernière mise à jour : 2026-09-02

📚 Références scientifiques (Chicago Author-Date) (1 sources)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: Formule brute · Masse moléculaire · Nom IUPAC · SMILES · InChIKey

RECHERCHE SCIENTIFIQUE

[1]PubMed2026
Betrancourt A, Cinko MT, Varanda AB et al.. (2026). "Lysine-11 ubiquitination drives type-I/III interferon induction by cGAS-STING and Toll-like receptors 3 and 4.". Nature cell biology. https://doi.o
[2]PubMed2026
Cheng Y, Tian Y, Chen H et al.. (2026). "Lysine malonylation regulates human sperm motility.". Communications biology. https://doi.org/10.1038/s42003-026-09683-y
[3]PubMed2026
Yuan Y, Xiao Y, Zou J et al.. (2026). "Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar.". Na
[4]PubMed2026
Schmöker O, Girbardt B, Schulze S et al.. (2026). "Reprogramming of bacterial virulence by lysine acetylation.". Nature communications. https://doi.org/10.1038/s41467-026-72244-8
[5]PubMed2025
Zhao F, Wang J, Liang W et al.. (2025). "Lysine restriction attenuates obesity-related anxiety-like behaviors via increasing Oscillibacter ruminantium-mediated tryptophol regulation.". Microbiome. htt
[6]PubMed2025
Xu G, Liang S, Hu G et al.. (2025). "HDAC2 as a therapeutic target in bladder cancer: insights into the altered epigenetic regulation and lysine lactylation.". Journal of experimental & clinical cance
[7]PubMed2025
Yan M, Tu H, Tang S et al.. (2025). "Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.". Molecular & cellular proteomics : MCP. https://doi.org/
[8]CrossRef2020
(2020). "Glutamic Acid Hydrochloride". Definitions. https://doi.org/10.32388/dn1lg6
📚 Références scientifiques (Chicago Author-Date) 10 refs · 2 baz

MOLECULE Bibliographie par CAS (en direct depuis 13+ bases de données)

Sources : db:pubmed (7) · db:crossref (3)

  1. db:pubmed Betrancourt A, Cinko MT, Varanda AB et al.. (2026). "Lysine-11 ubiquitination drives type-I/III interferon induction by cGAS-STING and Toll-like receptors 3 and 4.". Nature cell biology. https://doi.org/10.1038/s41556-026-01886-z
  2. db:pubmed Cheng Y, Tian Y, Chen H et al.. (2026). "Lysine malonylation regulates human sperm motility.". Communications biology. https://doi.org/10.1038/s42003-026-09683-y
  3. db:pubmed Yuan Y, Xiao Y, Zou J et al.. (2026). "Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar.". Nature communications. https://doi.org/10.1038/s41467-026-69388-y
  4. db:pubmed Schmöker O, Girbardt B, Schulze S et al.. (2026). "Reprogramming of bacterial virulence by lysine acetylation.". Nature communications. https://doi.org/10.1038/s41467-026-72244-8
  5. db:pubmed Zhao F, Wang J, Liang W et al.. (2025). "Lysine restriction attenuates obesity-related anxiety-like behaviors via increasing Oscillibacter ruminantium-mediated tryptophol regulation.". Microbiome. https://doi.org/10.1186/s40168-025-02217-4
  6. db:pubmed Xu G, Liang S, Hu G et al.. (2025). "HDAC2 as a therapeutic target in bladder cancer: insights into the altered epigenetic regulation and lysine lactylation.". Journal of experimental & clinical cancer research : CR. https://doi.org/10.1186/s13046-025-03610-5
  7. db:pubmed Yan M, Tu H, Tang S et al.. (2025). "Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.". Molecular & cellular proteomics : MCP. https://doi.org/10.1016/j.mcpro.2025.101439
  8. db:crossref (2020). "Glutamic Acid Hydrochloride". Definitions. https://doi.org/10.32388/dn1lg6
  9. db:crossref Zhimao Zhou, Yixin Qu, Shui Wang et al.. (2013). "Comment on “Measurement and Correlation of the Solubility of 2,6-Diaminohexanoic Acid Hydrochloride in Aqueous Methanol and Aqueous Ethanol Mixtures”". Journal of Chemical & Engineering Data. https://doi.org/10.1021/je300525z
  10. db:crossref Hua Sun, Min Li, Jingtan Jia et al.. (2012). "Measurement and Correlation of the Solubility of 2,6-Diaminohexanoic Acid Hydrochloride in Aqueous Methanol and Aqueous Ethanol Mixtures". Journal of Chemical & Engineering Data. https://doi.org/10.1021/je300173v
Statut réglementaire de la substance
Aucune entrée pour ce CAS dans les listes de restrictions vérifiées (liste candidate SVHC, REACH Annexe XVII ; ensembles de données incomplets - il ne s'agit pas d'une confirmation de conformité). Classification CLP et statut de transport (ADR) : voir la section GHS et la fiche de données de sécurité (SDS).
🧪 Données chimiques
Numéro CAS
657-27-2
Formule brute
C₆H₁₅ClN₂O₂
Masse molaire
182.65 g/mol
Nom IUPAC (EN)
(2S)-2,6-diaminohexanoic acid;hydrochloride
SMILES
C(CCN)C[C@@H](C(=O)O)N.Cl
InChIKey
BVHLGVCQOALMSV-JEDNCBNOSA-N
🔍 Identifiants externes
12 sur 16 systèmes d'ID75%
Base de donnéesIdentifiantActions
CAS Registry Number657-27-2Ouvrir →
PubChem CID69568[1]Ouvrir →
InChIKeyBVHLGVCQOALMSV-JEDNCBNOSA-N[1]Ouvrir →
InChIInChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5…[1]
SMILESC(CCN)C[C@@H](C(=O)O)N.Cl[1]
EC Number211-519-9[2]Ouvrir →
ChEMBLCHEMBL2105886[3]Ouvrir →
HMDBHMDB0301757Ouvrir →
ChemSpider62772[4]Ouvrir →
UNII (FDA)JNJ23Q2COMOuvrir →
NSC Number (NCI)9253Ouvrir →
WikiData QIDQ27124123Ouvrir →

Sources : PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Références scientifiques (Chicago Author-Date) (4 sources)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · InChI · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChEMBL. European Bioinformatics Institute (EMBL-EBI), bioactivity database. dotyczy: ChEMBL
  4. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

Dalsza literatura

Publications topically related to this CAS. They are not the source of any value given on this card.

Bibliographie (étendue) (5)

  1. ★★☆☆☆ CROSSREF 🔓 LIBRE ❓ non vérifié Anonymous. 2023. "RP1052 Assessment of the Application for L-lysine Monohydrochloride and Concentrated Liquid L-lysine (Base) Produced by Fermentation With Corynebacterium Glutamicum KCCM 80216 or KCTC 12307BP as a Feed Additive for All Animal Species." FSA Research and Evidence. https://doi.org/10.46756/001c.157938. lien [consulté: 2026-09-02] CC0 (metadata)
  2. ★★☆☆☆ CROSSREF 🔓 LIBRE ❓ non vérifié Anonymous. 2014. "Scientific Opinion on the safety and efficacy of concentrated liquid L‐lysine (base), concentrated liquid L‐lysine monohydrochloride and L‐lysine monohydrochloride technically pure produced using Escherichia coli (FERM BP‐11355) for all animal species based on a dossier submitted by Ajinomoto Eurolysine S.A.S." EFSA Journal 12 (11). https://doi.org/10.2903/j.efsa.2014.3895. lien [consulté: 2026-09-02] CC0 (metadata)
  3. ★★☆☆☆ CROSSREF 🔓 LIBRE ❓ non vérifié Anonymous. 2013. "Scientific opinion on the safety and efficacy of concentrated liquid L‐lysine (base), concentrated liquid L‐lysine monohydrochloride and L‐lysine monohydrochloride produced by Escherichia coli (FERM BP‐10941) for all animal species, based on three dossiers submitted by Ajinomoto Eurolysine SAS." EFSA Journal 11 (10). https://doi.org/10.2903/j.efsa.2013.3365. lien [consulté: 2026-09-02] CC0 (metadata)
  4. ★★☆☆☆ CROSSREF 🔓 LIBRE ❓ non vérifié Anonymous. 2004. "<scp>L</scp> ‐Lysine Monohydrochloride 657‐27‐2." Sax's Dangerous Properties of Industrial Materials. https://doi.org/10.1002/0471701343.sdp15835. lien [consulté: 2026-09-02] CC0 (metadata)
  5. ★★☆☆☆ CROSSREF 🔓 LIBRE ❓ non vérifié Anonymous. "l-Lysine Monohydrochloride.". https://doi.org/10.31003/fcc_f101016_05_01. lien [consulté: 2026-09-02] CC0 (metadata)

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Pharmaceutical Grade L-Lysine Hydrochloride — CAS 657-27-2. Listed by Xilong Scientific. Prepared from the supplier’s public catalogue; not verified against their internal data.

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