N,N-Dimethylacetamide (CAS 127-19-5)
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N,N-Dimethylacetamide. CAS 127-19-5.
⚠️ Note: This safety data sheet is provided in English; a localized version is being prepared.
Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.
Section 9 — physicochemical properties: 10 of 22 established.
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Daten transkribiert aus regulatorischen Registern und Fachliteratur, unter Angabe von Quelle und Ausgabe. Sie ersetzen nicht das Sicherheitsdatenblatt des Lieferanten. Felder ohne hinterlegte Quelle sind als solche gekennzeichnet.
Chemische Übersicht: Dimethylacetamide
| Summenformel | C4H9NO[1] |
| Molekulargewicht | 87.12 g/mol[1] |
| LogP (Lipophilie) | -0.8[1] |
| IUPAC-Name | N,N-dimethylacetamide[1] |
| SMILES | CC(=O)N(C)C[1] |
| InChIKey | FXHOOIRPVKKKFG-UHFFFAOYSA-N[1] |
Synonyme: N,N-DIMETHYLACETAMIDE · 127-19-5 · Dimethylacetamide · Acetamide, N,N-dimethyl- · Acetdimethylamide
Datenquellen: PubChem (NLM/NIH)
Zuletzt aktualisiert: 2026-09-02
📚 Wissenschaftliche Referenzen (Chicago Author-Date) (1 Quellen)
- PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. ↗ dotyczy: Summenformel · Molekulargewicht · LogP (Lipophilie) · IUPAC-Name · SMILES · InChIKey
WISSENSCHAFTLICHE FORSCHUNG
📚 Wissenschaftliche Referenzen (Chicago Author-Date) 16 refs · 3 baz
MOLECULE Bibliografie pro CAS (live aus 13+ Datenbanken)
Quellen: db:pubmed (13) · db:semantic_scholar (2) · db:crossref (1)
- db:pubmed Nomiyama T, Tsukahara T, Hasegawa K. (2025). "Health risks of N,N-dimethylacetamide (DMAC) in humans.". Journal of occupational health. https://doi.org/10.1093/joccuh/uiaf010 →
- db:pubmed Wei ZH, Koya J, Acharekar N et al.. (2023). "N,N-dimethylacetamide targets neuroinflammation in Alzheimer's disease in in-vitro and ex-vivo models.". Scientific reports. https://doi.org/10.1038/s41598-023-34355-w →
- db:pubmed Yuan B, Yao J, Wang Z et al.. (2022). "Increasing N,N-dimethylacetamide degradation and mineralization efficiency by co-culture of Rhodococcus ruber HJM-8 and Paracoccus communis YBH-X.". Chemosphere. https://doi.org/10.1016/j.chemosphere.2022.134935 →
- db:pubmed Zaniboni L, Madeddu M, Mosca F et al.. (2022). "Concentration dependent effect of dimethylacetamide and N-methylacetamide on the quality and fertility of cryopreserved chicken semen.". Cryobiology. https://doi.org/10.1016/j.cryobiol.2022.04.001 →
- db:pubmed Gatti NLS , Corcini CD , Filho JS et al.. (2021). "Dimethylacetamide in Rooster Semen Cryopreservation.". Cryo letters.
- db:pubmed Khera N, Ghayor C, Lindholm AK et al.. (2020). "N, N-Dimethylacetamide, an FDA approved excipient, acts post-meiotically to impair spermatogenesis and cause infertility in rats.". Chemosphere. https://doi.org/10.1016/j.chemosphere.2020.127001 →
- db:pubmed Ali N, Hamouda HI, Su H et al.. (2020). "Combinations of alkaline hydrogen peroxide and lithium chloride/N,N-dimethylacetamide pretreatments of corn stalk for improved biomethanation.". Environmental research. https://doi.org/10.1016/j.envres.2020.109563 →
- db:pubmed Gorasiya S, Mushi J, Pekson R et al.. (2018). "Repurposing N,N-Dimethylacetamide (DMA), a Pharmaceutical Excipient, as a Prototype Novel Anti-inflammatory Agent for the Prevention and/or Treatment of Preterm Birth.". Current pharmaceutical design. https://doi.org/10.2174/1381612824666180130121706 →
- db:pubmed Du P , Rick SW , Kumar R . (2018). "Towards a coarse-grained model of the peptoid backbone: the case of N,N-dimethylacetamide.". Physical chemistry chemical physics : PCCP. https://doi.org/10.1039/c8cp03283a →
- db:pubmed Chen X, Yang C, Wang W et al.. (2017). "Biodegradation of N,N-dimethylacetamide by Rhodococcus sp. strain B83 isolated from the rhizosphere of pagoda tree.". Journal of environmental sciences (China). https://doi.org/10.1016/j.jes.2016.05.013 →
- db:semantic_scholar Ahmad Rohi Ghazali, S. Inayat-Hussain. (2014). "N,N-Dimethylacetamide". https://doi.org/10.1016/B978-0-12-386454-3.01223-9 →
- db:pubmed Sundaram S, Ashby CR Jr, Pekson R et al.. (2013). "N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth.". The American journal of pathology. https://doi.org/10.1016/j.ajpath.2013.05.006 →
- db:crossref (2012). "N,N‐Dimethylacetamide 127‐19‐5". Sax's Dangerous Properties of Industrial Materials. https://doi.org/10.1002/0471701343.sdp09566.pub2 →
- db:pubmed Morris JP 4th, Berghmans S, Zahrieh D et al.. (2003). "Zebrafish sperm cryopreservation with N,N-dimethylacetamide.". BioTechniques. https://doi.org/10.2144/03355st03 →
- db:pubmed Tanaka S, Nomiyama T, Miyauchi H et al.. (2002). "Monitoring for N,N-dimethylformamide and N,N-dimethylacetamide with a diffusive sampler using distilled water as an absorbent.". AIHA journal : a journal for the science of occupational and environmental health and safety. https://doi.org/10.1080/15428110208984762 →
- db:semantic_scholar T. Nomiyama, K. Omae, C. Ishizuka et al.. (2000). "Dermal absorption of N,N-dimethylacetamide in human volunteers". International Archives of Occupational and Environmental Health. https://doi.org/10.1007/S004200050017 →
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N,N-Dimethylacetamide — CAS 127-19-5. Listed by Xilong Scientific. Prepared from the supplier’s public catalogue; not verified against their internal data.