Luteolin (CAS 491-70-3)
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Luteolin. CAS 491-70-3. 20mg.
⚠️ Note: This safety data sheet is provided in English; a localized version is being prepared.
Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.
Section 9 — physicochemical properties: 4 of 22 established.
We show what is established and name what is not. Classification and identity are complete on every card; section 9 is where public data is thin.
Identity, structure, physical and chemical properties, analytical data and the literature — every value with the source it came from and the date that source was read. The full record is in the data sections further down this page.
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数据转录自法规登记册和专业文献，并注明来源与版本。不能替代供应商的安全数据表。未记录来源的字段已作相应标注。
化学概述: Luteolin
| 分子式 | C15H10O6[1] |
| 分子量 | 286.24 g/mol[1] |
| LogP（亲脂性） | 1.4[1] |
| IUPAC名称 | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one[1] |
| SMILES | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O[1] |
| InChIKey | IQPNAANSBPBGFQ-UHFFFAOYSA-N[1] |
同义词: luteolin · 491-70-3 · 3',4',5,7-Tetrahydroxyflavone · Digitoflavone · Luteolol
数据来源： PubChem (NLM/NIH)
最后更新： 2026-09-03
📚 科学参考文献（芝加哥作者-日期格式） (1 来源)
- PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. ↗ applies to: 分子式 · 分子量 · LogP（亲脂性） · IUPAC名称 · SMILES · InChIKey
科学研究
📚 科学参考文献（芝加哥作者-日期格式） 12 refs · 1 baz
MOLECULE 按CAS号参考文献（实时来自13+数据库）
来源： db:pubmed (12)
- db:pubmed Luo L, Huang F, Fang G et al.. (2026). "Luteolin Inhibits NLRP3 Inflammasome Activation to Ameliorate DSS-Induced Colitis by Regulating AMPK Signalling.". Cell proliferation. https://doi.org/10.1111/cpr.70134 →
- db:pubmed Hao X, Yuan S, Ning J et al.. (2025). "Luteolin improves precancerous conditions of the gastric mucosa by binding STAT3 and inhibiting LCN2 expression.". International journal of biological sciences. https://doi.org/10.7150/ijbs.111636 →
- db:pubmed Gu M, Pang Z. (2025). "Luteolin inhibits inflammation and M1 macrophage polarization in the treatment of Pseudomonas aeruginosa-induced acute pneumonia through suppressing EGFR/PI3K/AKT/NF-κB and EGFR/ERK/AP-1 signaling pathways.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2025.156663 →
- db:pubmed Ye Z, Yang S, Chen L et al.. (2025). "Luteolin alleviated calcium oxalate crystal induced kidney injury by inhibiting Nr4a1-mediated ferroptosis.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2024.156302 →
- db:pubmed Cao Q, Ding S, Zheng X et al.. (2025). "Luteolin Induces GPX4-dependent Ferroptosis and Enhances Immune Activation in Colon Cancer.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2025.157117 →
- db:pubmed Zhu M, Sun Y, Su Y et al.. (2024). "Luteolin: A promising multifunctional natural flavonoid for human diseases.". Phytotherapy research : PTR. https://doi.org/10.1002/ptr.8217 →
- db:pubmed Chai S, Yang Y, Wei L et al.. (2024). "Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2024.155516 →
- db:pubmed Han Z, Batudeligen, Chen H et al.. (2024). "Luteolin attenuates CCl4-induced hepatic injury by inhibiting ferroptosis via SLC7A11.". BMC complementary medicine and therapies. https://doi.org/10.1186/s12906-024-04486-2 →
- db:pubmed Zhang N, Chen P, Liang X et al.. (2024). "Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis.". Aging. https://doi.org/10.18632/aging.205969 →
- db:pubmed Li Y, Wang Y, Ding Y et al.. (2024). "A Double Network Composite Hydrogel with Self-Regulating Cu(2+)/Luteolin Release and Mechanical Modulation for Enhanced Wound Healing.". ACS nano. https://doi.org/10.1021/acsnano.4c04816 →
- db:pubmed Quan J, Xie D, Li Z et al.. (2024). "Luteolin alleviates airway remodeling in asthma by inhibiting the epithelial-mesenchymal transition via β-catenin regulation.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2024.156090 →
- db:pubmed Yu X, Xu L, Su C et al.. (2024). "Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy.". The AAPS journal. https://doi.org/10.1208/s12248-024-00982-y →
Why this page can be checked
Identity
CAS, EC and molecular formula, resolved across the identifier systems a buyer uses. The count of systems resolved is shown, so you can see how well characterised this substance is rather than assuming.
Data
Every physicochemical value carries the source it came from and the date that source was read. Open any of them.
Classification
Read against the harmonised entry where one exists, with the index number stated. Self-classification is shown separately and labelled.
Regulatory
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Documentation
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The Gap Report Guarantee
If the available evidence cannot support a defensible document for your CAS number and product specification, we will not invent the missing values. You receive a documented gap report and choose: a refund, store credit, or the report on its own.
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If a signed card is rejected by an authority or by a customer’s compliance officer on one of the points we checked and reported as passed, we re-issue it corrected at no charge and credit the original fee.
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Luteolin — CAS 491-70-3, purity 分析对照品试剂, 20mg. Listed by Beijing Tong Guang. Prepared from the supplier’s public catalogue; not verified against their internal data.