Ethyl Acetate (CAS 141-78-6)

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Ethyl Acetate. CAS 141-78-6.

⚠️ Note: This safety data sheet is provided in English; a localized version is being prepared.

Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.

REACH 2020/878
v1 · 02.09.2026

Section 9 — physicochemical properties: 14 of 22 established.

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Chemisch overzicht: Ethyl Acetate
MolecuulformuleC4H8O2[1]
Molecuulmassa88.11 g/mol[1]
Smeltpunt-83.6 °C[2][3]
Kookpunt77.1 °C (760 mmHg)[2][3]
Dichtheid0.9003 g/cm³[2]
LogP (lipofiliteit)0.73[1]
IUPAC-naamethyl acetate[1]
SMILESCCOC(=O)C[1]
InChIKeyXEKOWRVHYACXOJ-UHFFFAOYSA-N[1]

Synoniemen: ETHYL ACETATE · 141-78-6 · Ethyl ethanoate · Acetic acid ethyl ester · Vinegar naphtha

Gegevensbronnen: PubChem (NLM/NIH), Reid, Prausnitz, Poling 4th ed. (1987)
Laatst bijgewerkt: 2026-09-02

📚 Wetenschappelijke referenties (Chicago Author-Date) (3 bronnen)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: Molecuulformule · Molecuulmassa · LogP (lipofiliteit) · IUPAC-naam · SMILES · InChIKey
  2. DECHEMA, PTB, and BAM. CHEMSAFE - Database of Evaluated Safety Characteristics for the Avoidance of Explosions. Frankfurt am Main: DECHEMA e.V.; Braunschweig/Berlin: Physikalisch-Technische Bundesanstalt and Bundesanstalt fur Materialforschung und -prufung. dotyczy: Smeltpunt · Kookpunt · Dichtheid
  3. NIST. Chemistry WebBook, SRD 69. National Institute of Standards and Technology. dotyczy: Smeltpunt · Kookpunt

WETENSCHAPPELIJK ONDERZOEK

[1]PubMed2026
Zhu W, Chen R, Wu L et al.. (2026). "Ethyl acetate fraction from Dendrobium officinale inhibits IL-17A signaling pathway to mitigate acute lung injury.". Journal of ethnopharmacology. https://doi.org/
[2]PubMed2026
Zeng J, Tang Y, Zhao A et al.. (2026). "Ethyl acetate fraction of Chaidangbo prescription (EAFC) improves hippocampal neural plasticity in CUMS mice: involving glucocorticoid receptors and Akt-related
[3]Europe PMC2026
et al.. (2026). "The Role of Ethyl Acetate Fraction from Phyllanthus amarus in Down-Regulation of Allergic Inflammatory Responses.". https://doi.org/10.3390/molecules31111806
[4]Europe PMC2026
et al.. (2026). "Ethyl acetate extract from Platycladus orientalis leaves ameliorates diabetic cardiomyopathy via alleviating oxidative stress and suppressing myocardial fibrosis.". https://doi.org/10
[5]Europe PMC2026
(2026). "2-(Propyloxy)ethyl acetate: MAK Value Documentation, addendum - Translation of the German version from 2024.". https://doi.org/10.34865/mb280730e11_1ad
[6]Europe PMC2026
(2026). "A Safe Natural Alternative to Phenylthiourea: Ethyl Acetate Extract of Alchemilla vulgaris for Zebrafish Embryo Depigmentation.". https://doi.org/10.3390/ph19050714
[7]Europe PMC2026
et al.. (2026). "Experimental and Modeling Assessment of Polyphenol Solubility in Alcohol + Ethyl Acetate Mixtures for Extraction Applications.". https://doi.org/10.1021/acsomega.5c10953
[8]Europe PMC2026
et al.. (2026). "A non-conventional biodiesel process route from waste palm fatty acid distillate and ethyl acetate via esterification.". https://doi.org/10.1038/s41598-026-41785-9
📚 Wetenschappelijke referenties (Chicago Author-Date) 23 refs · 2 baz

MOLECULE Bibliografie per CAS (live uit 13+ databases)

Bronnen: db:pubmed (10) · db:Europe PMC (14)

  1. db:pubmed Zhu W, Chen R, Wu L et al.. (2026). "Ethyl acetate fraction from Dendrobium officinale inhibits IL-17A signaling pathway to mitigate acute lung injury.". Journal of ethnopharmacology. https://doi.org/10.1016/j.jep.2026.121176
  2. db:pubmed Zeng J, Tang Y, Zhao A et al.. (2026). "Ethyl acetate fraction of Chaidangbo prescription (EAFC) improves hippocampal neural plasticity in CUMS mice: involving glucocorticoid receptors and Akt-related signaling pathway.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2026.158411
  3. db:Europe PMC et al.. (2026). "The Role of Ethyl Acetate Fraction from Phyllanthus amarus in Down-Regulation of Allergic Inflammatory Responses.". https://doi.org/10.3390/molecules31111806
  4. db:Europe PMC et al.. (2026). "Ethyl acetate extract from Platycladus orientalis leaves ameliorates diabetic cardiomyopathy via alleviating oxidative stress and suppressing myocardial fibrosis.". https://doi.org/10.3389/fphar.2026.1771512
  5. db:Europe PMC (2026). "2-(Propyloxy)ethyl acetate: MAK Value Documentation, addendum - Translation of the German version from 2024.". https://doi.org/10.34865/mb280730e11_1ad
  6. db:Europe PMC (2026). "A Safe Natural Alternative to Phenylthiourea: Ethyl Acetate Extract of Alchemilla vulgaris for Zebrafish Embryo Depigmentation.". https://doi.org/10.3390/ph19050714
  7. db:Europe PMC et al.. (2026). "Experimental and Modeling Assessment of Polyphenol Solubility in Alcohol + Ethyl Acetate Mixtures for Extraction Applications.". https://doi.org/10.1021/acsomega.5c10953
  8. db:Europe PMC et al.. (2026). "A non-conventional biodiesel process route from waste palm fatty acid distillate and ethyl acetate via esterification.". https://doi.org/10.1038/s41598-026-41785-9
  9. db:Europe PMC et al.. (2026). "In Vitro and In Silico Investigations of Antifungal Activity of Ethyl Acetate Extracts of Various Species of Swertia Against Aspergillus fumigatus.". https://doi.org/10.1002/cbdv.71468
  10. db:Europe PMC et al.. (2026). "Antibacterial and toxicological evaluation of (E)-2-((3,7-dimethylocta-2,6-dien-1-yl)oxy)ethyl acetate.". https://doi.org/10.1590/1519-6984.302367
  11. db:Europe PMC et al.. (2026). "Fluorination Site and Degree Regulate the Decomposition of Fluorinated Ethyl Acetate Solvents on Lithium Metal: A First-Principles Molecular Dynamics Study.". https://doi.org/10.3390/nano16130810
  12. db:Europe PMC et al.. (2026). "Ethyl acetate extract of Elephantopus mollis Kunth. induced apoptosis, senescence, and inhibited metastasis-associated traits of human lung cancer cells.". https://doi.org/10.4103/rps.rps_115_25
  13. db:pubmed Yu Q, Shao P, Liu X et al.. (2025). "Ethyl acetate extract of Sargentodoxa cuneata and Patrinia villosa alleviates pelvic inflammation by shifting macrophages polarization.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2025.157345
  14. db:pubmed Liu Y, Yu T, Liu M et al.. (2025). "Artemisia argyi ethyl acetate fraction suppresses ovarian cancer progression via JUN/MAPK10 signaling: An integrated multi-omics investigation.". Phytomedicine : international journal of phytotherapy and phytopharmacology. https://doi.org/10.1016/j.phymed.2025.157533
  15. db:pubmed Zhao M, Zeng L, Zhou Y et al.. (2025). "Ethyl Acetate Fraction of Zanthoxylum bungeanum Ameliorates Cognitive Deficit by Facilitating the PHGDH-Dependent Astrocyte-Neuron Serine Shuttle in Aging Mice.". Journal of agricultural and food chemistry. https://doi.org/10.1021/acs.jafc.4c12077
  16. db:pubmed Liu MJ, Xu ZP, Guan YQ et al.. (2025). "Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.". Journal of ethnopharmacology. https://doi.org/10.1016/j.jep.2024.118776
  17. db:pubmed Suryaningtyas IT, Jung WK, Lee SJ et al.. (2025). "Salicornia europaea L. Ethyl Acetate Fraction Induces Adipocyte Browning and Exhibits Anti-Obesity Effect in 3T3-L1 Preadipocytes.". Chemistry & biodiversity. https://doi.org/10.1002/cbdv.202501190
  18. db:Europe PMC et al.. (2025). "Direct Conversion of Ethanol to Ethyl Acetate by Dynamic Polyoxometalate/Carbon Nanohorn Electrocatalytic Interfaces.". https://doi.org/10.1021/jacs.5c10817
  19. db:Europe PMC et al.. (2025). "Toxicity Profile of Plectranthus glandulosus Hook. F. (Lamiaceae) Aqueous Extract, Hydro-Ethanolic Extract, and Ethyl Acetate Fraction.". https://doi.org/10.1155/bri/7453400
  20. db:Europe PMC et al.. (2025). "Exploring a Water-Ethyl Acetate System for the Efficient Synthesis of 4-Aryl Quinolines.". https://doi.org/10.1002/open.202400470
  21. db:Europe PMC et al.. (2025). "Mycochemistry, antioxidant activity and anticancer potentiality of ethyl acetate extract of Daldinia eschscholtzii against A549 lung cancer cell line.". https://doi.org/10.1038/s41598-025-22756-y
  22. db:pubmed Zhang S, Hou B, Xu A et al.. (2024). "Ganlu formula ethyl acetate extract (GLEE) blocked the development of experimental arthritis by inhibiting NLRP3 activation and reducing M1 type macrophage polarization.". Journal of ethnopharmacology. https://doi.org/10.1016/j.jep.2024.118377
  23. db:pubmed Williams ES, Ryder VE. (2023). "Spaceflight Maximum Allowable Concentrations for Ethyl Acetate.". Aerospace medicine and human performance. https://doi.org/10.3357/AMHP.6057.2023
Regelgevingsstatus van de stof
Deze stof is onderworpen aan reglementaire vereisten: beheer van gevaarlijke afvalstoffen (BDO-register). Details in de sectie "Regelgevingsstatus (REACH/ECHA/CLP)" en op de SDS. Regelgevingsinformatie — beperkt de aankoop in deze winkel niet.
🧪 Chemische gegevens
CAS-nummer
141-78-6
Molecuulformule
C4H8O2
Molaire massa
88.11 g/mol
IUPAC-naam (EN)
ethyl acetate
SMILES
CCOC(=O)C
InChIKey
XEKOWRVHYACXOJ-UHFFFAOYSA-N
⚗️ Physicochemical properties
Temp. wrzenia
77.1
Temp. topnienia
-83.2
Density
0.9

Source: PubChem, NIST WebBook. Last updated: 2026-09-02

🔍 Externe identificatoren
13 van 16 ID-systemen81%
DatabaseIdentificatorActies
CAS Registry Number141-78-6Openen →
PubChem CID8857[1]Openen →
InChIKeyXEKOWRVHYACXOJ-UHFFFAOYSA-N[1]Openen →
InChIInChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3[1]
SMILESCCOC(=O)C[1]
EC Number205-500-4[2]Openen →
ChEMBLCHEMBL14152[3]Openen →
KEGG CompoundD02319Openen →
HMDBHMDB0031217Openen →
ChemSpider8525[4]Openen →
UNII (FDA)76845O8NMZOpenen →
NSC Number (NCI)70930Openen →
WikiData QIDQ407153Openen →

Bronnen: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Wetenschappelijke referenties (Chicago Author-Date) (4 bronnen)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · InChI · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChEMBL. European Bioinformatics Institute (EMBL-EBI), bioactivity database. dotyczy: ChEMBL
  4. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

Dalsza literatura

Publications topically related to this CAS. They are not the source of any value given on this card.

Bibliografie (uitgebreid) (5)

  1. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ niet-geverifieerd Anonymous. "Specification for Ethyl Acetate (All Grades).". https://doi.org/10.1520/d4614-11. link [geraadpleegd: 2026-09-02] CC0 (metadata)
  2. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ niet-geverifieerd Anonymous. "Specification for Ethyl Acetate (All Grades).". https://doi.org/10.1520/d4614-05. link [geraadpleegd: 2026-09-02] CC0 (metadata)
  3. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ niet-geverifieerd Anonymous. "Specification for Ethyl Acetate (All Grades).". https://doi.org/10.1520/d4614. link [geraadpleegd: 2026-09-02] CC0 (metadata)
  4. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ niet-geverifieerd Anonymous. "Specification for Ethyl Acetate (All Grades).". https://doi.org/10.1520/d4614-95. link [geraadpleegd: 2026-09-02] CC0 (metadata)
  5. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ niet-geverifieerd Anonymous. "Specification for Ethyl Acetate (All Grades).". https://doi.org/10.1520/d4614-11r19. link [geraadpleegd: 2026-09-02] CC0 (metadata)

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Ethyl Acetate — CAS 141-78-6. Listed by Xilong Scientific. Prepared from the supplier’s public catalogue; not verified against their internal data.

Gegevens van PubChemBron: PubChem (NIH) · ChEMBL