CAS 139-33-3

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Динатриевая соль этилендиаминтетрауксусной кислоты ЭДТА (Трилон Б; EDTA. CAS 139-33-3.

⚠️ Note: This safety data sheet is provided in English; a localized version is being prepared.

Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.

REACH 2020/878
v1 · 03.09.2026

Section 9 — physicochemical properties: 1 of 22 established.

We show what is established and name what is not. Classification and identity are complete on every card; section 9 is where public data is thin.

What is in the buyer pack

Everything your compliance officer will ask for, in one file.

  • The product page as PDF — the record as published, so what you forward matches what you read.
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  • The specification, and the certificate of analysis where batch data exists.
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Your European buyer is going to forward this to somebody who was not on the call. The pack exists so that what they forward is complete, self-explanatory and traceable — rather than four attachments and a sentence beginning “I think this is everything”.

These switch the language of this page. Single substances. Mixtures on enquiry. One document, one language — additional languages are priced separately. Every version, including the Chinese one, is written to EU law — (EC) No 1907/2006 (REACH) Annex II and (EU) 2020/878 — and translated from it. The Chinese version is a reference translation, not a legally valid document for the Chinese market: an SDS for China must be compiled separately to GB/T 16483 and GB/T 17519.

Dane transkrybowane z rejestrów regulacyjnych i literatury fachowej, z podaniem źródła i wydania. Nie zastępują karty charakterystyki dostawcy. Pola bez zapisanego źródła oznaczone jako takie.

Przegląd chemiczny: EDTA disodium salt
Wzór sumarycznyC₁₀H₁₄N₂Na₂O₈
Masa cząsteczkowa336.21 g/mol
Nazwa IUPACdisodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate
SMILESC(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].[Na+].[Na+]
InChIKeyZGTMUACCHSMWAC-UHFFFAOYSA-L

Synonimy: 139-33-3 · EDTA disodium salt · Disodium EDTA · Edta disodium · Titriplex III

Data sources: PubChem (NLM/NIH)
Last updated: 2026-09-03

BADANIA NAUKOWE

[1]PubMed2026
Ornowska M, Wittmann J, Blitz S et al.. (2026). "4% Tetrasodium EDTA to Prevent Central Venous Access Device-Associated Complications: A Randomized Clinical Trial.". JAMA. https://doi.org/10.1001/jama
[2]PubMed2026
Buteau JP, Moon D, Fahey MT et al.. (2026). "Effect of [(68)Ga]Ga-PSMA-11 PET-CT in the diagnosis of prostate cancer in men with equivocal or clinically high-risk non-suspicious findings on multiparam
[3]PubMed2026
Gronauer TF, Merl-Pham J, von Toerne C et al.. (2026). "Blood Matrices and Sample Preparation Influence Blood Marker Discovery.". Journal of proteome research. https://doi.org/10.1021/acs.jproteome.5c
[4]PubMed2026
Giesel FL, Koerber SA, Hadaschik B et al.. (2026). "The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 (68)Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer
[5]PubMed2026
Khan S, Papa N, Kneebone A et al.. (2026). "Prospective Comparison of (64)Copper [(64)Cu]SAR-bisPSMA vs (68)Gallium[(68)Ga] PSMA-11 PET/CT for Biochemical Recurrence of Prostate Cancer Following Radic
[6]PubMed2026
Muñoz A, Fontanés Ulloa M, Madrigal G et al.. (2026). "Uso del protocolo de higiene de la herida para controlar biofilm y optimizar costos en heridas de difícil cicatrización: casos de estudio.". Jour
[7]PubMed2026
Küçüker C, Kaya G, Ergün EL et al.. (2026). "Imaging Discordance Between [⁶⁸Ga]-PSMA PET and [¹⁷⁷Lu]-PSMA SPECT in mCRPC.". Clinical nuclear medicine. https://doi.org/10.1097/RLU.0000000000006293
[8]PubMed2025
Ujueta F, Lamas GA, Anstrom KJ et al.. (2025). "Multivitamins After Myocardial Infarction in Patients With Diabetes: A Randomized Clinical Trial.". JAMA internal medicine. https://doi.org/10.1001/jama
📚 Naukowe referencje (Chicago Author-Date) 20 refs · 2 baz

MOLECULE Bibliografia per-CAS (live z 13+ baz)

Źródła: db:pubmed (15) · db:crossref (5)

  1. db:pubmed Ornowska M, Wittmann J, Blitz S et al.. (2026). "4% Tetrasodium EDTA to Prevent Central Venous Access Device-Associated Complications: A Randomized Clinical Trial.". JAMA. https://doi.org/10.1001/jama.2026.6025
  2. db:pubmed Buteau JP, Moon D, Fahey MT et al.. (2026). "Effect of [(68)Ga]Ga-PSMA-11 PET-CT in the diagnosis of prostate cancer in men with equivocal or clinically high-risk non-suspicious findings on multiparametric MRI (PRIMARY2): a multicentre, non-inferiority, phase 3, randomised controlled trial.". The Lancet. Oncology. https://doi.org/10.1016/S1470-2045(26)00120-8
  3. db:pubmed Gronauer TF, Merl-Pham J, von Toerne C et al.. (2026). "Blood Matrices and Sample Preparation Influence Blood Marker Discovery.". Journal of proteome research. https://doi.org/10.1021/acs.jproteome.5c00836
  4. db:pubmed Giesel FL, Koerber SA, Hadaschik B et al.. (2026). "The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 (68)Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer: Safety and diagnostic accuracy compared to histopathology and their impact on patient management.". European journal of nuclear medicine and molecular imaging. https://doi.org/10.1007/s00259-025-07540-4
  5. db:pubmed Khan S, Papa N, Kneebone A et al.. (2026). "Prospective Comparison of (64)Copper [(64)Cu]SAR-bisPSMA vs (68)Gallium[(68)Ga] PSMA-11 PET/CT for Biochemical Recurrence of Prostate Cancer Following Radical Prostatectomy (Co-PSMA Trial).". European urology. https://doi.org/10.1016/j.eururo.2026.03.001
  6. db:pubmed Muñoz A, Fontanés Ulloa M, Madrigal G et al.. (2026). "Uso del protocolo de higiene de la herida para controlar biofilm y optimizar costos en heridas de difícil cicatrización: casos de estudio.". Journal of wound care. https://doi.org/10.12968/jowc.2026.0252
  7. db:pubmed Küçüker C, Kaya G, Ergün EL et al.. (2026). "Imaging Discordance Between [⁶⁸Ga]-PSMA PET and [¹⁷⁷Lu]-PSMA SPECT in mCRPC.". Clinical nuclear medicine. https://doi.org/10.1097/RLU.0000000000006293
  8. db:pubmed Ujueta F, Lamas GA, Anstrom KJ et al.. (2025). "Multivitamins After Myocardial Infarction in Patients With Diabetes: A Randomized Clinical Trial.". JAMA internal medicine. https://doi.org/10.1001/jamainternmed.2024.8408
  9. db:pubmed Huang Y, Wan S, Wen X et al.. (2025). "Fracture of retraction fibers is crucial for the harvesting of migrasomes.". Cell communication and signaling : CCS. https://doi.org/10.1186/s12964-025-02495-3
  10. db:pubmed Abaza MM, Harhash TAH, Zaky AA. (2025). "Comparative analysis of laser and ultrasonic irrigation techniques for smear layer removal in endodontics.". Lasers in medical science. https://doi.org/10.1007/s10103-025-04766-4
  11. db:pubmed Zhang H, Jiang X, Yang G et al.. (2025). "Machine learning-based construction and validation of an radiomics model for predicting ISUP grading in prostate cancer: a multicenter radiomics study based on [68Ga]Ga-PSMA PET/CT.". European journal of nuclear medicine and molecular imaging. https://doi.org/10.1007/s00259-025-07412-x
  12. db:pubmed Beintner-Skawran S, Gafita A, Lorenzini T et al.. (2025). "[(68)Ga]Ga-PSMA-11 PET Tumor Volume Predicts Overall Survival of Patients with Metastatic Prostate Cancer Undergoing Taxane-Based Chemotherapy.". Journal of nuclear medicine : official publication, Society of Nuclear Medicine. https://doi.org/10.2967/jnumed.125.269584
  13. db:pubmed Ballal NV, Narkedamalli R, Shenoy PA et al.. (2025). "Biological and chemical properties of new multi-functional root canal irrigants.". Journal of dentistry. https://doi.org/10.1016/j.jdent.2024.105551
  14. db:pubmed Fiorillo L, D'Amico C, Meto A et al.. (2024). "Sodium Hypochlorite Accidents in Endodontic Practice: Clinical Evidence and State of the Art.". The Journal of craniofacial surgery. https://doi.org/10.1097/SCS.0000000000010407
  15. db:pubmed Pabst KM, Mei R, Lückerath K et al.. (2024). "Detection of tumour heterogeneity in patients with advanced, metastatic castration-resistant prostate cancer on [(68)Ga]Ga-/[(18)F]F-PSMA-11/-1007, [(68)Ga]Ga-FAPI-46 and 2-[(18)F]FDG PET/CT: a pilot study.". European journal of nuclear medicine and molecular imaging. https://doi.org/10.1007/s00259-024-06891-8
  16. db:crossref (2018). "PPS News". International Polymer Processing. https://doi.org/10.3139/217.018014
  17. db:crossref Adil ÇORUK. (2014). "YÜKSEKÖĞRETİM KURUMLARINDA GÖREV YAPAN İ". Ondokuz Mayis Univ. Egitim Fakultesi. https://doi.org/10.7822/egt171
  18. db:crossref (2013). "Conclusion". Clinical Drug Investigation. https://doi.org/10.1007/s40261-012-0038-9
  19. db:crossref (1984). "33". Country Teacher. https://doi.org/10.1515/9780824887841-035
  20. db:crossref (1898). "The Spectator". Notes and Queries. https://doi.org/10.1093/nq/s9-ii.33.139b
Status regulacyjny substancji
Brak wpisów dla tego CAS w sprawdzonych wykazach ograniczeń (lista kandydacka SVHC, REACH Załącznik XVII; zbiory niepełne - nie jest to potwierdzenie zgodności). Klasyfikacja CLP i status transportowy (ADR): patrz sekcja GHS oraz karta charakterystyki (SDS).
🧪 Dane chemiczne
Numer CAS
139-33-3
Wzór sumaryczny
C₁₀H₁₄N₂Na₂O₈
Masa molowa
336.21 g/mol
Nazwa IUPAC (EN)
disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate
SMILES
C(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].[Na+].[Na+]
InChIKey
ZGTMUACCHSMWAC-UHFFFAOYSA-L
🔍 Identyfikatory zewnętrzne
12 z 16 systemów ID75%
BazaIdentyfikatorAkcje
CAS Registry Number139-33-3Otwórz →
PubChem CID8759[1]Otwórz →
InChIKeyZGTMUACCHSMWAC-UHFFFAOYSA-L[1]Otwórz →
SMILESC(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].[Na…[1]
EC Number205-358-3[2]Otwórz →
DrugBankDB14600Otwórz →
KEGG CompoundD03945Otwórz →
HMDBHMDB0303556Otwórz →
ChemSpider8429[3]Otwórz →
UNII (FDA)8NLQ36F6MMOtwórz →
NSC Number (NCI)2760Otwórz →
WikiData QIDQ4532977Otwórz →

Źródła: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Naukowe referencje (Chicago Author-Date) (3 źródeł)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

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Динатриевая соль этилендиаминтетрауксусной кислоты ЭДТА (Трилон Б; EDTA — CAS 139-33-3. Listed by Uts Shanghai. Prepared from the supplier’s public catalogue; not verified against their internal data.

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