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Safety data sheet documentation for 1,2-dichloroethane (CAS 107-06-2), compiled to REACH Annex II with classification read against the harmonised entry in CLP Annex VI (H225, H350, H302, H335). Two options: a working draft sent by e-mail immediately, or a signed card issued within 72 hours of complete input. The item supplied is a document — MolGod.org does not sell, supply or ship chemical substances.
Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.
第 9 部分 — 理化特性:已确定 12 项,共 22 项。
我们展示已确定的内容,并指明尚未确定的内容。每张卡片上的分类和标识信息都是完整的;公开数据较少的是第9部分。
标识、结构、物理和化学性质、分析数据及文献 — 每个数值均注明其来源及该来源的查阅日期。完整记录见本页下方的数据部分。
标识符覆盖情况以数量显示,而非质量评级。它说明该物质在公开数据中的表征程度 — 这与物质本身好坏是不同的问题;在判断其背后的文件是否站得住脚时,这个问题更有用。
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该物质可提供的文件: 安全数据表 · CLP 标签 · 分析证书(应要求提供) · 规格书。语言:您目标市场的官方语言,按每份文件单独制作。
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合规专员会检查哪些内容,以及它们在文件中的位置。具体数值见下方的法规部分。
尚无确定状态的字段会如实注明。本页从不声明不适用任何限制 — 未出现在数据集中并不等于获准,而将其视为获准的文件是该领域最危险的一类文件。
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sources.txt — 每条引用均注明查阅日期。您的欧洲买方会把这些资料转发给没有参加通话的人。资料包的意义在于,让其转发的内容完整、不言自明且可追溯 — 而不是四个附件加一句以 “我想就这些了” 开头的话。
这些选项用于切换本页面的语言。 Single substances. Mixtures on enquiry. One document, one language — additional languages are priced separately. Every version, including the Chinese one, is written to EU law — (EC) No 1907/2006 (REACH) Annex II and (EU) 2020/878 — and translated from it. The Chinese version is a reference translation, not a legally valid document for the Chinese market: an SDS for China must be compiled separately to GB/T 16483 and GB/T 17519.
数据转录自法规登记册和专业文献,并注明来源与版本。不能替代供应商的安全数据表。未记录来源的字段已作相应标注。
C(CCl)Cl 最后更新: 2026-08-25
| 分子式 | C2H4Cl2[1] |
| 分子量 | 98.96 g/mol[1] |
| 熔点 | -35.56 °C |
| 沸点 | 83.5 °C[2] |
| 密度 | 1.2 g/cm³ |
| LogP(亲脂性) | 1.5[1] |
| IUPAC名称 | 1,2-dichloroethane[1] |
| SMILES | C(CCl)Cl[1] |
| InChIKey | WSLDOOZREJYCGB-UHFFFAOYSA-N[1] |
同义词: 1,2-dichloroethane · Ethylene dichloride · 107-06-2 · Ethylene chloride · Glycol dichloride
数据来源: PubChem (NLM/NIH)
最后更新: 2026-08-25
科学研究
MOLECULE 按CAS号参考文献(实时来自13+数据库)
来源: db:pubmed (3) · db:Europe PMC (1)
GHS/CLP分类——(EC) No 1272/2008法规 + UN GHS Rev. 9 (2021)。
✓ 根据CLP法规(EC) 1272/2008附件VI的统一分类(官方、具有约束力的分类)。 索引号:602-012-00-7。
参考文献(芝加哥格式): European Chemicals Agency. "1,2-dichloroethane; ethylene dichloride, Index No. 602-012-00-7." In Table 3 of Annex VI to Regulation (EC) No 1272/2008 (CLP Regulation), 23rd Adaptation to Technical Progress (harmonised list as of 2026-07-07). Helsinki: European Chemicals Agency, 2026. https://echa.europa.eu/information-on-chemicals/annex-vi-to-clp.
翻译:CLP 法规 (EC) 1272/2008,附件 III 和 IV。数据:PubChem/NLM。
从所有Safety Hub选项卡收集的参考文献。CAS号: 107-06-2 ·
PubChem ↗
具有自身参考文献的选项卡(紧急情况、个人防护装备、储存、废物)在其各自章节中包含额外的书目条目。
粘贴一系列重复测量结果(CSV或每行一个数字)。计算器将计算平均值、标准差和95%置信区间,并检测异常值(Grubbs + Dixon Q)。
x̄ = Σxᵢ / n — 算术平均值s² = Σ(xᵢ - x̄)² / (n-1) — 样本方差s = √s² — 标准差RSD% = (s / x̄) × 100% — 相对标准差CI₉₅ = x̄ ± t(0.05, n-1) × s / √n — Student's tG = |xᵢ - x̄| / s — Grubbs检验Q = |xsuspect - xnearest| / |xmax - xmin| — Dixon Q-test来源:ICH Q2(R2) 分析方法验证 · ICH PDF ↗
从 20 种常用缓冲体系列表中选择 → 输入目标 pH → 获得精确配方,包括称量质量。
规划您的整个实验室项目:添加实验(含试剂、重复次数和持续时间)。您将获得甘特图、购物清单(含商店链接!)、预算(含10%余量)和GHS风险矩阵。
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类药性雷达图(Lipinski Ro5 / Veber)。绿色区域 = 符合标准。
预测数据 — 通过计算机模拟(SMILES/RDKit)计算的属性。不能替代临床研究。未经实验验证,不得用于药物评估。
| 属性 | 值 | 评级 |
|---|---|---|
| 吸收(GI) | 高 | ✓ |
| 血脑屏障通透性 | 是(可透过) | |
| 生物利用度(Daina 2017) | 55% | |
| CYP450概况 | CYP1A2 non-inhibitorCYP2C9 non-inhibitorCYP2C19 non-inhibitorCYP2D6 non-inhibitorCYP3A4 non-inhibitor | |
| PAINS警告 | 0 | ✓ |
| Brenk警告 | 0 | ✓ |
| pKa (pH 7.4) | — | |
| hERG(心脏毒性) | ✓ 否 | |
| P-gp底物 | — | |
| Ames致突变性 | ⚠ 是 | |
| DILI(肝毒性) | — | |
| LogS(水溶性) | — | |
107-06-2
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CAS、EC 和分子式,已在买方使用的各标识符系统中完成解析。页面显示已解析的系统数量,让您看到该物质的表征程度,而不是凭假设。
每个理化数值都标明其来源及该来源的查阅日期。任何一条都可以打开查看。
如有统一分类条目,则以其为准并注明索引号。自我分类单独列出并加以标注。
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If the available evidence cannot support a defensible document for your CAS number and product specification, we will not invent the missing values. You receive a documented gap report and choose: a refund, store credit, or the report on its own.
A visible gap is worth more than a plausible number, because the plausible number is the one that fails when somebody checks it.
If a signed card is rejected by an authority or by a customer’s compliance officer on one of the points we checked and reported as passed, we re-issue it corrected at no charge and credit the original fee.
This covers the checks we performed and named. It does not cover registration status, tonnage, or your role in the supply chain — those are not ours to hold, and a guarantee that pretended otherwise would be worth nothing.
1,2-dichloroethane carries a harmonised entry in CLP Annex VI under index 602-012-00-7. This page covers the safety data sheet issued for it — a document, not a supply of the material.
The first-aid information for CAS 107-06-2 must be understandable and actionable by someone without a chemistry background when following instructions under time pressure. Section 4 includes additional notes intended for medical professionals, where the classification’s clinical relevance is detailed.
Section 14 for CAS 107-06-2 includes the UN number, correct shipping name, class, packing group, and environmental hazard where applicable. If the substance is not hazardous for transportation, Section 14 explicitly states this rather than being left empty; an empty Section 14 is interpreted as an omission rather than a lack of hazard.
The supply label for 1,2-dichloroethane is generated from the same classification that drives the safety data sheet: pictograms selected by precedence, one signal word derived from the highest hazard class present, and the hazard statements H225, H350, H302… reproduced in full. Where the container is too small to carry the complete set at a legible size, there are lawful ways to handle it and unlawful ones that look identical to a non-specialist.
Whoever brings 1,2-dichloroethane across the Union border carries the documentation duty, and it does not transfer back up the supply chain by contract. Section 1 has to name a contactable entity inside the Union: a foreign address there is treated as no address at all, and it is among the first things an inspector verifies because it takes seconds.
CAS 107-06-2 has a recorded presence on the European trading market, which means documentation for it is requested routinely rather than exceptionally. Substances that move in commerce attract repeat scrutiny: the same sheet is read by successive customers, carriers and authorities, and a defect that survives the first reading rarely survives the tenth.
When a consignment of 1,2-dichloroethane is stopped at the border, the document examined first is rarely the invoice. It is section 14 of the safety data sheet and its agreement with the transport papers. A missing packing group, an absent UN number or a proper shipping name that contradicts the classification of CAS 107-06-2 will hold the pallet regardless of how complete the remaining fifteen sections are.
Yes — 1,2-dichloroethane appears on the candidate list of substances of very high concern. That triggers duties that classification alone does not: notification to ECHA above the tonnage threshold, and an obligation to inform recipients where the substance is present in an article above 0.1 % by weight. It is also listed in Annex XIV, with a sunset date of 2017-11-22. Once a substance reaches Annex XIV, continued use in the Union requires an authorisation granted for a named use — a supplier relationship alone is not a legal basis. Outside the Union the same substance appears on DSL — toxic (CA), TSCA (US). Exporters are read against the list of the destination, not of the origin.
CAS 107-06-2 is classified as a CMR substance (H350). That status changes the obligations attached to every shipment: workplace exposure documentation, restrictions on supply to the general public, and substitution pressure from downstream users who must justify continued use. A safety data sheet for a CMR substance is read more closely than any other, because the classification itself invites scrutiny.
Section 6 covers accidental release of 1,2-dichloroethane: personal precautions, environmental precautions and the containment method. Where the classification carries an aquatic hazard, the environmental part stops being a formality and becomes the operative instruction.
Bringing 1,2-dichloroethane into the Union is a documentation exercise before it is a logistics one. The file has to exist at the moment of import, not at the moment somebody asks for it, and for substances listed in CLP Annex VI it is examined in the context of regulated consignments. Index 602-012-00-7 fixes the classification that section 2 must reproduce.
If a document concerning 1,2-dichloroethane is already in circulation, the initial consideration should be whether it is incorrect rather than whether to replace it, and if incorrect, in which specific sections. Errors tend to recur across a range of documents; therefore, examining three documents often provides insights that would otherwise require reviewing three hundred.
The CAS 107-06-2 number and index number 602-012-00-7 are not interchangeable or decorative elements; they serve distinct purposes. The index number connects to the harmonised classification system, whereas the CAS number links to chemical literature. A document containing one without the other requires readers to independently reconstruct this relationship, which may lead to errors during reconstruction.
The label for 1,2-dichloroethane carries GHS02 (flame), GHS07 (exclamation mark), GHS08 (health hazard), with the signal word Danger. These are not chosen by the supplier: CLP Annex VI states them for CAS 107-06-2, and the precedence rules in Annex I decide which pictogram is dropped when two would say the same thing. A label showing a different set from the register is wrong even if every hazard statement on it is correct.
Alongside CAS 107-06-2, this substance carries EC number 203-458-1 and Annex VI index 602-012-00-7. European documentation is built around the EC number as often as around the CAS: registration dossiers, the candidate list and customs systems key on it. A safety data sheet quoting only one of the two forces every downstream reader to look up the other.
The harmonised classification for CAS 107-06-2 carries 6 hazard statements: H225, H350, H302, H335, H315, H319. In plain terms this means highly flammable liquid and vapour; may cause cancer; harmful if swallowed; may cause respiratory irritation. A harmonised entry is binding across the Union — an importer may not soften it, and a self-classification that diverges from it will not survive an enforcement check.
Yes. A section-by-section reading against Annex II and the current harmonised entry establishes that in one pass, and a sheet that passes is reported as passing.
Yes. A sheet compiled to Annex II of REACH must exist before the first consignment moves, and it must be held by the entity placing the substance on the Union market.
CAS 107-06-2. In CLP Annex VI the same substance carries index number 602-012-00-7, and both identifiers should appear in the documentation.
Yes. The harmonised classification places it among substances classified as carcinogenic, mutagenic or toxic for reproduction, which changes workplace documentation and supply restrictions.
MolGod.org issues documentation and does not sell, supply or ship chemical substances. CAS 107-06-2 identifies the subject of this document.
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| 文件用途 | 工作草稿 €49.99 |
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| 内部起草与审查 | Yes | Yes |
| 核查供应商发给您的数据表 | Yes | Yes |
| 发送给您的客户 | 并非为此编写 | Yes |
| 随出口货物一同寄运 | 并非为此编写 | Yes |
| 供检查员或主管机关审阅 | 并非为此编写 | Yes |
| 根据您的公司、等级和已确定用途进行调整 | No | Yes |
| 由审核人签名并注明日期 | No | Yes |
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以上折叠面板中针对CAS号107-06-2引用的所有科学来源。格式: 《芝加哥格式手册》第17版,作者-日期系统.