L-Valine
CAS 72-18-4 · C5H11NO2 · MW 117.15 g/mol
Scientific literature
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12 articles · 7 open access · Sources: PubMed, OpenAlex, Semantic Scholar
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The application of 4 in the solid-phase synthesis of polo-like kinase 1 (Plk1) polo box domain (PBD)-binding peptides retain PBD binding efficacy similar to a parent pThr containing peptide should be a highly useful reagent for the preparation of signal transduction-directed peptides.
It is indicated that significant amounts of PhIP are bioavailable from ingestion of fried or char-broiled meats, and that urinary PhIP metabolites reflect recent (12-24h) ingestion, and significant interindividual differences in the amounts of urine PhIP metabolite excreted are observed following ingestion of similar amounts ofPhIP.
In vivo and in vitro neuronal activities of both enantiomers of IKM-159 prepared by enantioselective asymmetric synthesis are reported, consistent with a pharmacological action as competitive antagonist of AMPA receptors.
(R,S)-2-Amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid is a potent and selective agonist at the N- methyl-D-aspartic acid (NMDA) subtype of excitatory amino acid receptors.
Perioperative intravenous infusion of a balanced amino acid solution safely reduces the incidence and severity of AKI and improves renal functional parameters after cardiac surgery with CPB, supporting its use as an early nephroprotective strategy.
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