L-Valine

CAS 72-18-4  ·  C5H11NO2  ·  MW 117.15 g/mol

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3D model L-Valine, CAS 72-18-4, molecular formula C5H11NO2, molar mass 117.15 g/mol
About L-Valine

L-Valine is a chemical compound registered under number CAS 72-18-4, with the molecular formula C5H11NO2, and a molar mass of 117.15 g/mol.

The molecule contains 19 atoms connected by 18 chemical bonds. The full systematic IUPAC name of this compound is (2S)-2-amino-3-methylbutanoic acid. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = -2.3 (negative value, a hydrophilic compound), polar surface area PSA = 63.3 Ų, 2 donors and 3 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The widget above may be used for educational, research and commercial purposes.

Physicochemical properties
Molecular formulaC5H11NO2
Masa molowa117.15 g/mol
IUPAC(2S)-2-amino-3-methylbutanoic acid
SMILESCC(C)[C@@H](C(=O)O)N
InChIKeyKZSNJWFQEVHDMF-BYPYZUCNSA-N
logP (XLogP3)-2.3
PSA63.3 Ų
HBD / HBA2 / 3
PubChem CIDCID 6287 ↗
Scientific literature

Related literature

12 articles · 7 open access · Sources: PubMed, OpenAlex, Semantic Scholar

Filtry:Eksport:📄 BibTeX📑 RIS📋 EndNote🔧 CSL-JSON

📈 Publication timeline (12 articles)

1996: 1 articles19962002: 1 articles2009: 2 articles2010: 1 articles2011: 1 articles2013: 1 articles20132022: 1 articles2024: 2 articles2025: 1 articles2026: 1 articles2026

Bar height = number of articles per year. Hover dla szczegółów.

Fa Liu, Jung-Eun Park, Kyung S. Lee et al. (2009) · Tetrahedron
AI Summary
The application of 4 in the solid-phase synthesis of polo-like kinase 1 (Plk1) polo box domain (PBD)-binding peptides retain PBD binding efficacy similar to a parent pThr containing peptide should be a highly useful reagent for the preparation of signal transduction-directed peptides.
Cytowania: 26Influential: 1Open AccessDOI ↗PubMed ↗PDF ↗
P. Strickland, Zheng Qian, M. Friesen et al. (2002) · Mutation research
AI Summary
It is indicated that significant amounts of PhIP are bioavailable from ingestion of fried or char-broiled meats, and that urinary PhIP metabolites reflect recent (12-24h) ingestion, and significant interindividual differences in the amounts of urine PhIP metabolite excreted are observed following ingestion of similar amounts ofPhIP.
Cytowania: 45Influential: 1$ PaywallDOI ↗PubMed ↗
L. Juknaitė, Yutaro Sugamata, K. Tokiwa et al. (2013) · Journal of Medicinal Chemistry
AI Summary
In vivo and in vitro neuronal activities of both enantiomers of IKM-159 prepared by enantioselective asymmetric synthesis are reported, consistent with a pharmacological action as competitive antagonist of AMPA receptors.
Cytowania: 20Open AccessDOI ↗PubMed ↗PDF ↗
T. Kasim, Andrey G. Yavorsky, I. Mandel et al. (2026) · Journal of Clinical Practice
AI Summary
Perioperative intravenous infusion of a balanced amino acid solution safely reduces the incidence and severity of AKI and improves renal functional parameters after cardiac surgery with CPB, supporting its use as an early nephroprotective strategy.
Open AccessDOI ↗PDF ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

Synonyms
L-valine · valine · 72-18-4 · (S)-Valine · (2S)-2-amino-3-methylbutanoic acid · (S)-2-Amino-3-methylbutanoic acid · 2-Amino-3-methylbutyric acid · (S)-2-Amino-3-methylbutyric acid · valina · L-alpha-Amino-beta-methylbutyric acid · L-valin · Valinum · (S)-alpha-Amino-beta-methylbutyric acid · NSC-76038 · l-(+)-alpha-Aminoisovaleric acid
Data sources
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License & Provenance

MolGod 3D molecular model
L-Valine — CAS 72-18-4

License: CC BY-SA 4.0 (source rights NIEUSTALONE — not yet granted for this model)

MolGod License & Provenance Record:
L-Valine (CAS 72-18-4) — License & Provenance

Source:
L-Valine (CAS 72-18-4) — MolGod molecule record

Source data: PubChem CID 6287

STL: Download 3D model (381 KB)

SHA-256: 3856ca8392740a0e99aef18524150c064377a54f9d4ddb28ff6aa54fe917c9e8

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Source data: PubChem CID 6287

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