4-Chloro-N-methylpicolinamide

CAS 220000-87-3  ·  C7H7ClN2O  ·  MW 170.59 g/mol

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3D模型4-Chloro-N-methylpicolinamide,CAS 220000-87-3,分子式C7H7ClN2O, 摩尔质量 170.59 g/mol
关于 4-Chloro-N-methylpicolinamide

4-Chloro-N-methylpicolinamide 是一种化学品,登记号为 CAS 220000-87-3,分子式为 C7H7ClN2O,摩尔质量为 170.59 g/mol。

该分子包含 18 个原子,通过 18 个化学键连接。 该化合物的完整系统 IUPAC 名称为 4-chloro-N-methylpyridine-2-carboxamide。 上方的交互式 3D 模型可查看原子的空间排列——您可以用鼠标旋转、用滚轮缩放,并在骨架 / 球棍 (Ball & Stick) / 空间填充 (Space Fill) 显示模式之间切换。

在理化性质方面, 分配系数 logP = 1.1 (正值,亲脂性化合物),极性表面积 PSA = 42 Ų,1 个氢键供体和 2 个氢键受体。 这些参数对于评估生物利用度以及与生物分子的相互作用至关重要。

该化合物的化学数据来自 PubChem(NIH NLM NCBI),全球最大的化学数据库之一。所有信息均自动更新,并附有符合 CLP 法规(EC 1272/2008)的 GHS 危险说明翻译。上方的小部件可用于教育、研究和商业用途。

理化性质
Molecular formulaC7H7ClN2O
Masa molowa170.59 g/mol
IUPAC4-chloro-N-methylpyridine-2-carboxamide
SMILESCNC(=O)C1=NC=CC(=C1)Cl
InChIKeyBGVBBMZMEKXUTR-UHFFFAOYSA-N
logP (XLogP3)1.1
PSA42 Ų
HBD / HBA1 / 2
PubChem CIDCID 1476814 ↗
GHS 安全

Signal word: Warning

GHS07
GHS07

H315 — Działa drażniąco na skórę

H319 — Działa drażniąco na oczy

H335 — Może powodować podrażnienie dróg oddechowych

科学文献

Related literature

20 articles · 10 open access · Sources: PubMed, OpenAlex, Semantic Scholar

Filtry:Eksport:📄 BibTeX📑 RIS📋 EndNote🔧 CSL-JSON

📈 Publication timeline (20 articles)

1987: 1 articles19871991: 1 articles1993: 1 articles2002: 1 articles2005: 1 articles2006: 1 articles2016: 1 articles2017: 1 articles20172018: 2 articles2020: 2 articles2021: 1 articles2022: 1 articles2023: 2 articles2024: 3 articles2026: 1 articles2026

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Christopher J L Aleksandr Y Peng Cristiana Kaja M Mohsen Foad Murray Aravkin Zheng Abbafati Abbas Abbasi-Kangeva, C. Murray, A. Aravkin et al. (2020) · The Lancet
AI Summary
The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.
Cytowania: 6049Influential: 361Open AccessDOI ↗PubMed ↗PDF ↗
E. Chelysheva, J. Apperley, A. Turkina et al. (2024) · Leukemia
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Treatment options balance the efficacy and safety for mother and infant: interferon-α can commence in the 1st trimester and continued throughout in cases of good disease control and tolerability and selected tyrosine kinase inhibitors seem to be safe and effective options in 2nd and 3rd trimester while hydroxycarbamide offers few benefits.
Cytowania: 24Influential: 1Open AccessDOI ↗PubMed ↗PDF ↗
Walid El Ansari, A. El-Menyar, Kareem El-Ansari et al. (2024) · Obesity Surgery
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This study is the first to generate detailed estimates of the incidence and patterns of VTE after MBS over time, and North American and earlier studies had higher incidence than non-North American and more recent studies.
Cytowania: 15Influential: 3Open AccessDOI ↗PubMed ↗PDF ↗
Q. Li, Lingxiao Wang, Chao Tang et al. (2023) · Molecular Neurobiology
AI Summary
The current study showed that the Drosophila brain could obtain circ_sxc by uptake of adipose tissue exosomes which crossed the blood-brain barrier and suppressed brain miR-87-3p expression through sponge adsorption, which regulated the expression of neurological receptor ligand proteins and ensured brain neuronal synaptic signaling normal function of synaptic signaling.
Cytowania: 11$ PaywallDOI ↗PubMed ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

同义词
220000-87-3 · 4-Chloro-N-methylpicolinamide · 4-Chloro-N-methylpyridine-2-carboxamide · RefChem:521896 · DTXCID80314152 · 606-888-1 · N-Methyl-4-chloropyridine-2-carboxamide · 4-Chloro-N-methyl-2-pyridinecarboxamide · MFCD02185921 · 2-Pyridinecarboxamide, 4-chloro-N-methyl- · N-METHYL 4-CHLOROPICOLINAMIDE · Sorafenib Tosylate Impurity P · CHEMBL4163507 · 4-Chloro-N-methylpyridine-2-carboxamide (>90%) · AKOS001123699
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