4-Chloro-N-methylpicolinamide

CAS 220000-87-3  ·  C7H7ClN2O  ·  MW 170.59 g/mol

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3D model 4-Chloro-N-methylpicolinamide, CAS 220000-87-3, molecular formula C7H7ClN2O, molar mass 170.59 g/mol
About 4-Chloro-N-methylpicolinamide

4-Chloro-N-methylpicolinamide is a chemical compound registered under number CAS 220000-87-3, with the molecular formula C7H7ClN2O, and a molar mass of 170.59 g/mol.

The molecule contains 18 atoms connected by 18 chemical bonds. The full systematic IUPAC name of this compound is 4-chloro-N-methylpyridine-2-carboxamide. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = 1.1 (positive value, a lipophilic compound), polar surface area PSA = 42 Ų, 1 donors and 2 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The widget above may be used for educational, research and commercial purposes.

Physicochemical properties
Molecular formulaC7H7ClN2O
Masa molowa170.59 g/mol
IUPAC4-chloro-N-methylpyridine-2-carboxamide
SMILESCNC(=O)C1=NC=CC(=C1)Cl
InChIKeyBGVBBMZMEKXUTR-UHFFFAOYSA-N
logP (XLogP3)1.1
PSA42 Ų
HBD / HBA1 / 2
PubChem CIDCID 1476814 ↗
GHS safety

Signal word: Warning

GHS07
GHS07

H315 — Działa drażniąco na skórę

H319 — Działa drażniąco na oczy

H335 — Może powodować podrażnienie dróg oddechowych

Scientific literature

Related literature

20 articles · 10 open access · Sources: PubMed, OpenAlex, Semantic Scholar

Filtry:Eksport:📄 BibTeX📑 RIS📋 EndNote🔧 CSL-JSON

📈 Publication timeline (20 articles)

1987: 1 articles19871991: 1 articles1993: 1 articles2002: 1 articles2005: 1 articles2006: 1 articles2016: 1 articles2017: 1 articles20172018: 2 articles2020: 2 articles2021: 1 articles2022: 1 articles2023: 2 articles2024: 3 articles2026: 1 articles2026

Bar height = number of articles per year. Hover dla szczegółów.

Christopher J L Aleksandr Y Peng Cristiana Kaja M Mohsen Foad Murray Aravkin Zheng Abbafati Abbas Abbasi-Kangeva, C. Murray, A. Aravkin et al. (2020) · The Lancet
AI Summary
The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.
Cytowania: 6049Influential: 361Open AccessDOI ↗PubMed ↗PDF ↗
E. Chelysheva, J. Apperley, A. Turkina et al. (2024) · Leukemia
AI Summary
Treatment options balance the efficacy and safety for mother and infant: interferon-α can commence in the 1st trimester and continued throughout in cases of good disease control and tolerability and selected tyrosine kinase inhibitors seem to be safe and effective options in 2nd and 3rd trimester while hydroxycarbamide offers few benefits.
Cytowania: 24Influential: 1Open AccessDOI ↗PubMed ↗PDF ↗
Walid El Ansari, A. El-Menyar, Kareem El-Ansari et al. (2024) · Obesity Surgery
AI Summary
This study is the first to generate detailed estimates of the incidence and patterns of VTE after MBS over time, and North American and earlier studies had higher incidence than non-North American and more recent studies.
Cytowania: 15Influential: 3Open AccessDOI ↗PubMed ↗PDF ↗
Q. Li, Lingxiao Wang, Chao Tang et al. (2023) · Molecular Neurobiology
AI Summary
The current study showed that the Drosophila brain could obtain circ_sxc by uptake of adipose tissue exosomes which crossed the blood-brain barrier and suppressed brain miR-87-3p expression through sponge adsorption, which regulated the expression of neurological receptor ligand proteins and ensured brain neuronal synaptic signaling normal function of synaptic signaling.
Cytowania: 11$ PaywallDOI ↗PubMed ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

Synonyms
220000-87-3 · 4-Chloro-N-methylpicolinamide · 4-Chloro-N-methylpyridine-2-carboxamide · RefChem:521896 · DTXCID80314152 · 606-888-1 · N-Methyl-4-chloropyridine-2-carboxamide · 4-Chloro-N-methyl-2-pyridinecarboxamide · MFCD02185921 · 2-Pyridinecarboxamide, 4-chloro-N-methyl- · N-METHYL 4-CHLOROPICOLINAMIDE · Sorafenib Tosylate Impurity P · CHEMBL4163507 · 4-Chloro-N-methylpyridine-2-carboxamide (>90%) · AKOS001123699
Data sources
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License & Provenance

MolGod 3D molecular model
4-Chloro-N-methylpicolinamide — CAS 220000-87-3

License: CC BY-SA 4.0 (source rights NIEUSTALONE — not yet granted for this model)

MolGod License & Provenance Record:
4-Chloro-N-methylpicolinamide (CAS 220000-87-3) — License & Provenance

Source:
4-Chloro-N-methylpicolinamide (CAS 220000-87-3) — MolGod molecule record

Source data: PubChem CID 1476814

STL: Download 3D model (366 KB)

SHA-256: 9c8d56764afc546f81d2e5b307a917c6f3195e8dd822364c4a95e1bea054b3ff

Wikimedia Commons: not published yet

Source data: PubChem CID 1476814

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