Emtricitabine

Emtricitabine is a chemical compound registered under number CAS 143491-57-0, with the molecular formula C₈H₁₀FN₃O₃S, and a molar mass of 247.25 g/mol.

The molecule contains 26 atoms connected by 27 chemical bonds. The full systematic IUPAC name of this compound is 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = -0.6 (negative value, a hydrophilic compound), polar surface area PSA = 113 Ų, 2 donors and 5 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The widget above may be used for educational, research and commercial purposes.

Molecular formula	C8H10FN3O3S
Masa molowa	247.25 g/mol
IUPAC	4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
SMILES	C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F
InChIKey	XQSPYNMVSIKCOC-NTSWFWBYSA-N
logP (XLogP3)	-0.6
PSA	113 Ų
HBD / HBA	2 / 5
PubChem CID	CID 60877 ↗

Emtricitabine · 143491-57-0 · Coviracil · Emtriva · 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one · 524W91 · dOTFC · BW-524W91 · 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one · 2-FTC · (-)-2'-Deoxy-5-fluoro-3'-thiacytidine · (-)-emtricitabine · 2'-Deoxy-5-fluoro-3'-thiacytidine · Emtricitabina · Emtricitabinum

• 📊 PubChem CID 60877 — NIH
• 🔬 NIST WebBook — spektroskopia
• 🌐 Wikidata
• 💊 ChEMBL — bioaktywność