N-(2-Hydroxyethyl)ethylenediamine (CAS 111-41-1)

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Аминоэтилэтаноламин (AEEA/АЭЭА). CAS 111-41-1.

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REACH 2020/878
v1 · 03.09.2026

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Chemical Overview: N-(2-Hydroxyethyl)ethylenediamine
Molecular formulaC4H12N2O
Molecular weight104.15 g/mol
LogP (lipophilicity)-1.7
IUPAC name2-(2-aminoethylamino)ethanol
SMILESC(CNCCO)N
InChIKeyLHIJANUOQQMGNT-UHFFFAOYSA-N

Synonyms: N-(2-Hydroxyethyl)ethylenediamine · monoethanol ethylenediamine · RefChem:112035 · 111-41-1 · 2-(2-Aminoethylamino)ethanol

Data sources: PubChem (NLM/NIH)
Last updated: 2026-09-02

SCIENTIFIC RESEARCH

[1]Semantic Scholar2024
Wan Meng, Lingyu Xiao, Liwang Wang et al.. (2024). "Experimental study on CO2 capture using 2‐(2‐aminoethylamino)ethanol/N,N‐diethyl‐ethanolamine/sulfolane phase‐change absorbents". Canadian Journal o
[2]CrossRef2023
(2023). "Review for "Experimental study on CO2 capture using 2‐(2‐aminoethylamino)ethanol/N,N‐diethyl‐ethanolamine/sulfolane phase‐change absorbents"". https://doi.org/10.1002/cjce.25176/v1/review1
[3]PubMed2022
Aso D, Orimoto Y, Higashino M et al.. (2022). "Why does 2-(2-aminoethylamino)ethanol have superior CO(2) separation performance to monoethanolamine? A computational study.". Physical chemistry chemica
[4]Semantic Scholar2022
Why does 2-(2-aminoethylamino)ethanol (AEEA) have superior CO 2 separation performance to monoethanolamine (MEA)?: A computational study
Daiki Asoa, Yuuichi Orimotob, Makoto Higashinoc et al.. (2022). "Why does 2-(2-aminoethylamino)ethanol (AEEA) have superior CO 2 separation performance to monoethanolamine (MEA)?: A computational stud
[5]CrossRef2021
Daiki Aso, Yuuichi Orimoto, Makoto Higashino et al.. (2021). "Computational approach for investigating the mechanism of carbon dioxide interaction by 2-(2-aminoethylamino)ethanol: A significant role o
[6]CrossRef2020
(2020). "Thermodynamic Modeling the Solubility of CO2 in Aqua System of Methyldiethanolamine and 2-(2-Aminoethylamino)ethanol Using the Nonelectrolyte Wilson Nonrandom Factor". International Journal o
[7]CrossRef2020
Ehsan Asadi, Ali Haghtalab, Habib Allah Shirazizadeh. (2020). "Experimental Measurement of Carbon Dioxide Solubility in Aqueous N-Methyldiethanolamine + 2-(2-Aminoethylamino) Ethanol + Sulfolane and D
[8]Semantic Scholar2017
Shuying Wu, Liangliang Zhang, Baochang Sun et al.. (2017). "Mass-Transfer Performance for CO2 Absorption by 2-(2-Aminoethylamino)ethanol Solution in a Rotating Packed Bed". https://doi.org/10.1021/ACS
📚 Scientific references (Chicago Author-Date) 14 refs · 4 baz

MOLECULE Per-CAS bibliography (live from 13+ databases)

Sources: db:semantic_scholar (6) · db:crossref (7) · db:pubmed (1) · db:doaj (1)

  1. db:semantic_scholar Wan Meng, Lingyu Xiao, Liwang Wang et al.. (2024). "Experimental study on CO2 capture using 2‐(2‐aminoethylamino)ethanol/N,N‐diethyl‐ethanolamine/sulfolane phase‐change absorbents". Canadian Journal of Chemical Engineering. https://doi.org/10.1002/cjce.25176
  2. db:crossref (2023). "Review for "Experimental study on CO2 capture using 2‐(2‐aminoethylamino)ethanol/N,N‐diethyl‐ethanolamine/sulfolane phase‐change absorbents"". https://doi.org/10.1002/cjce.25176/v1/review1
  3. db:pubmed Aso D, Orimoto Y, Higashino M et al.. (2022). "Why does 2-(2-aminoethylamino)ethanol have superior CO(2) separation performance to monoethanolamine? A computational study.". Physical chemistry chemical physics : PCCP. https://doi.org/10.1039/d2cp01136k
  4. db:semantic_scholar Daiki Asoa, Yuuichi Orimotob, Makoto Higashinoc et al.. (2022). "Why does 2-(2-aminoethylamino)ethanol (AEEA) have superior CO 2 separation performance to monoethanolamine (MEA)?: A computational study".
  5. db:crossref Daiki Aso, Yuuichi Orimoto, Makoto Higashino et al.. (2021). "Computational approach for investigating the mechanism of carbon dioxide interaction by 2-(2-aminoethylamino)ethanol: A significant role of water molecule". Chemical Physics Letters. https://doi.org/10.1016/j.cplett.2021.139070
  6. db:crossref (2020). "Thermodynamic Modeling the Solubility of CO2 in Aqua System of Methyldiethanolamine and 2-(2-Aminoethylamino)ethanol Using the Nonelectrolyte Wilson Nonrandom Factor". International Journal of Engineering. https://doi.org/10.5829/ije.2020.33.12c.01
  7. db:crossref Ehsan Asadi, Ali Haghtalab, Habib Allah Shirazizadeh. (2020). "Experimental Measurement of Carbon Dioxide Solubility in Aqueous N-Methyldiethanolamine + 2-(2-Aminoethylamino) Ethanol + Sulfolane and Diethanolamine + 2-(2-Aminoethylamino) Ethanol + Sulfolane Hybrid Solvents at Various Temperatures and High Pressure". Journal of Chemical & Engineering Data. https://doi.org/10.1021/acs.jced.0c00739
  8. db:semantic_scholar Shuying Wu, Liangliang Zhang, Baochang Sun et al.. (2017). "Mass-Transfer Performance for CO2 Absorption by 2-(2-Aminoethylamino)ethanol Solution in a Rotating Packed Bed". https://doi.org/10.1021/ACS.ENERGYFUELS.7B03002
  9. db:semantic_scholar Loghman Kord, M. Nasr‐Esfahani. (2015). "Corrosion behavior of carbon steel in HCl solution by Fe and Cr complexes with a Schiff-base ligand derived from salicylaldehyde and 2-(2-aminoethylamino)ethanol". https://doi.org/10.3103/S1068375515050087
  10. db:semantic_scholar H. Kierzkowska‐Pawlak, A. Chacuk, Marta Siemieniec. (2014). "Reaction kinetics of CO2 in aqueous 2-(2-aminoethylamino)ethanol solutions using a stirred cell reactor". https://doi.org/10.1016/J.IJGGC.2014.03.004
  11. db:crossref Sülin Taşcıoğlu, Bahattin Yalçın, Fatih Dumludağ et al.. (2013). "Synthesis in water-free DMF, characterization, electrical, and gas sensing properties of bis[2-(2-aminoethylamino)ethanol]copper(II) dibromide". Chemical Papers. https://doi.org/10.2478/s11696-013-0362-4
  12. db:doaj Reza Azadbakht, Hadi Amiri Rudbari, Giuseppe Bruno. (2011). "Bis[2-(2-aminoethylamino)ethanol]copper(II) dinitrate". Acta Crystallographica Section E. https://doi.org/10.1107/S1600536811030637
  13. db:crossref B. F. Kukharev, V. K. Stankevich, N. A. Lobanova et al.. (2007). "Reaction of acetylene with 2-(2-aminoethylamino)ethanol". Russian Journal of Organic Chemistry. https://doi.org/10.1134/s1070428007120263
  14. db:crossref Leon Segal, F. V. Eggerton. (1961). "Infrared Spectra of Diethylenetriamine and 2-(2-Aminoethylamino)ethanol". Applied Spectroscopy. https://doi.org/10.1366/000370261774426902
Regulatory status of the substance
This substance is subject to regulatory requirements: hazardous waste management (BDO register). Details in the \"Regulatory Status (REACH/ECHA/CLP)\" section and on the SDS. Regulatory information — does not restrict purchase in this store.
🧪 Chemical Data
CAS Number
111-41-1
Molecular formula
C4H12N2O
Molar mass
104.15 g/mol
IUPAC name (EN)
2-(2-aminoethylamino)ethanol
SMILES
C(CNCCO)N
InChIKey
LHIJANUOQQMGNT-UHFFFAOYSA-N
⚗️ Physicochemical properties
Density
1.028

Source: PubChem, NIST WebBook. Last updated: 2026-09-02

🔍 External identifiers
12 of 16 ID systems75%
DatabaseIdentifierActions
CAS Registry Number111-41-1Open →
PubChem CID8112[1]Open →
InChIKeyLHIJANUOQQMGNT-UHFFFAOYSA-N[1]Open →
InChIInChI=1S/C4H12N2O/c5-1-2-6-3-4-7/h6-7H,1-5H2[1]
SMILESC(CNCCO)N[1]
EC Number203-867-5[2]Open →
ChEMBLCHEMBL3186403[3]Open →
HMDBHMDB0244916Open →
ChemSpider7821[4]Open →
UNII (FDA)RC78W6NPXTOpen →
NSC Number (NCI)461Open →
WikiData QIDQ209289Open →

Sources: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Scientific references (Chicago Author-Date) (4 sources)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · InChI · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChEMBL. European Bioinformatics Institute (EMBL-EBI), bioactivity database. dotyczy: ChEMBL
  4. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

Dalsza literatura

Publications topically related to this CAS. They are not the source of any value given on this card.

Extended Bibliography (3)

  1. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Hall, J. 1976. "A polarographic study of the complexes formed in alkaline solution by the cadmium(II) ion with ethylenediamine, N-(2-hydroxyethyl)ethylenediamine, and N,N′-bis(2-hydroxyethyl)ethylenediamine." Journal of Electroanalytical Chemistry 68 (2): 217-222. https://doi.org/10.1016/0368-1874(76)80049-4. link [accessed: 2026-09-03] CC0 (metadata)
  2. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Zimmerman, Donald N., Hall, James L.. 1973. "Preparation, infrared spectra, visible reflectance spectra, and magnetic moments of copper(II) complexes of N,N'-di(2-hydroxyethyl)ethylenediamine, N-(2-hydroxyethyl)ethylenediamine, and N-(2-hydroxypropyl)ethylenediamine." Inorganic Chemistry 12 (11): 2616-2620. https://doi.org/10.1021/ic50129a025. link [accessed: 2026-09-03] CC0 (metadata)
  3. ★★☆☆☆ CROSSREF 🔓 OPEN ❓ unverified Hall, J. 1972. "A polarographic study of the complexes formed in alkaline solution by the copper(II) ion with ethylenediamine, N-(2-hydroxyethyl)ethylenediamine, and N,N′-bis(2-hydroxyethyl)ethylenediamine." Journal of Electroanalytical Chemistry 34 (2): 529-533. https://doi.org/10.1016/0368-1874(72)80030-3. link [accessed: 2026-09-03] CC0 (metadata)

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Аминоэтилэтаноламин (AEEA/АЭЭА) — CAS 111-41-1. Listed by Uts Shanghai. Prepared from the supplier’s public catalogue; not verified against their internal data.

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