D-Gluconic acid solution (CAS 526-95-4)

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D-Gluconic acid solution. CAS 526-95-4. 500ml.

Free, and generated automatically from the sources listed on this page. No person has reviewed it, and it describes the substance in general — not your material, your process or your intended market.

REACH 2020/878
v1 · 03.09.2026

Section 9 — physicochemical properties: 5 of 22 established.

We show what is established and name what is not. Classification and identity are complete on every card; section 9 is where public data is thin.

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Data transcribed from regulatory registers and technical literature, with the source and edition stated. It does not replace the supplier's safety data sheet. Fields without a recorded source are marked as such.

Chemical Overview: Gluconic Acid
Molecular formulaC6H12O7[1]
Molecular weight196.16 g/mol[1]
LogP (lipophilicity)-3.4[1]
IUPAC name(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid[1]
SMILESC([C@H]([C@H]([C@@H]([C@H](C(=O)O)O)O)O)O)O[1]
InChIKeyRGHNJXZEOKUKBD-SQOUGZDYSA-N[1]

Synonyms: gluconic acid · D-gluconic acid · 526-95-4 · dextronic acid · maltonic acid

Data sources: PubChem (NLM/NIH)
Last updated: 2026-09-03

📚 Scientific references (Chicago Author-Date) (1 sources)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: Molecular formula · Molecular weight · LogP (lipophilicity) · IUPAC name · SMILES · InChIKey

SCIENTIFIC RESEARCH

[1]PubMed2025
Del Rio EA, Valenzano MC, DiGuilio KM et al.. (2025). "Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a
[2]Semantic Scholar2024
Ling-Qiong Jiang, Ruo-Di Zhang, H. A. Musonye et al.. (2024). "Hormonal and reproductive factors in relation to the risk of rheumatoid arthritis in women: a prospective cohort study with 223 526 parti
[3]Semantic Scholar2024
Rohan Borschmann, S. Kinner. (2024). "Rates and causes of death after release from incarceration among 1 471 526 people in eight high-income and middle-income countries: an individual participant data
[4]PubMed2024
Nault D, Machingo TA, Shipper AG et al.. (2024). "Zinc for prevention and treatment of the common cold.". The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.CD014914.pub2
[5]PubMed2024
Devarshi PP, Mao Q, Grant RW et al.. (2024). "Comparative Absorption and Bioavailability of Various Chemical Forms of Zinc in Humans: A Narrative Review.". Nutrients. https://doi.org/10.3390/nu1624426
[6]PubMed2024
Furuichi M, Kawaguchi T, Pust MM et al.. (2024). "Commensal consortia decolonize Enterobacteriaceae via ecological control.". Nature. https://doi.org/10.1038/s41586-024-07960-6
[7]PubMed2024
Bergen A, Roemhild S, Santoro D. (2024). "Minimum inhibitory and bactericidal/fungicidal concentration of commercially available products containing essential oils, zinc gluconate, or 4% chlorhexidine
[8]Semantic Scholar2022
H. Shah, Kim Seongho, A. Halwani et al.. (2022). "HL-526 Improved Survival of Elderly Patients With Classical Hodgkin Lymphoma (cHL) in the Modern Era - A SEER-Registry Analysis.". Clinical Lymphoma,
📚 Scientific references (Chicago Author-Date) 18 refs · 3 baz

MOLECULE Per-CAS bibliography (live from 13+ databases)

Sources: db:pubmed (12) · db:semantic_scholar (7) · db:crossref (1)

  1. db:pubmed Del Rio EA, Valenzano MC, DiGuilio KM et al.. (2025). "Orally Administered Zinc Gluconate Induces Tight Junctional Remodeling and Reduces Passive Transmucosal Permeability Across Human Intestine in a Patient-Based Study.". International journal of molecular sciences. https://doi.org/10.3390/ijms26178540
  2. db:pubmed Furuichi M, Kawaguchi T, Pust MM et al.. (2024). "Commensal consortia decolonize Enterobacteriaceae via ecological control.". Nature. https://doi.org/10.1038/s41586-024-07960-6
  3. db:pubmed Bergen A, Roemhild S, Santoro D. (2024). "Minimum inhibitory and bactericidal/fungicidal concentration of commercially available products containing essential oils, zinc gluconate, or 4% chlorhexidine for Malassezia pachydermatis, Pseudomonas aeruginosa, and multi-drug resistant Staphylococcus pseudintermedius canine clinical isolates.". Veterinary research communications. https://doi.org/10.1007/s11259-024-10528-4
  4. db:semantic_scholar Ling-Qiong Jiang, Ruo-Di Zhang, H. A. Musonye et al.. (2024). "Hormonal and reproductive factors in relation to the risk of rheumatoid arthritis in women: a prospective cohort study with 223 526 participants". RMD Open. https://doi.org/10.1136/rmdopen-2023-003338
  5. db:semantic_scholar Rohan Borschmann, S. Kinner. (2024). "Rates and causes of death after release from incarceration among 1 471 526 people in eight high-income and middle-income countries: an individual participant data meta-analysis.". The Lancet. https://doi.org/10.1016/s0140-6736(24)00344-1
  6. db:pubmed Nault D, Machingo TA, Shipper AG et al.. (2024). "Zinc for prevention and treatment of the common cold.". The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.CD014914.pub2
  7. db:pubmed Devarshi PP, Mao Q, Grant RW et al.. (2024). "Comparative Absorption and Bioavailability of Various Chemical Forms of Zinc in Humans: A Narrative Review.". Nutrients. https://doi.org/10.3390/nu16244269
  8. db:semantic_scholar H. Shah, Kim Seongho, A. Halwani et al.. (2022). "HL-526 Improved Survival of Elderly Patients With Classical Hodgkin Lymphoma (cHL) in the Modern Era - A SEER-Registry Analysis.". Clinical Lymphoma, Myeloma & Leukemia. https://doi.org/10.1016/s2152-2650(22)00997-1
  9. db:semantic_scholar K. Heath, J. Levi, A. Hill. (2021). "The Joint United Nations Programme on HIV/AIDS 95–95–95 targets: worldwide clinical and cost benefits of generic manufacture". AIDS (London). https://doi.org/10.1097/QAD.0000000000002983
  10. db:pubmed Qiao Y, Li M, Qiu D et al.. (2019). "Response-Retaliation Behavior in Synthetic Protocell Communities.". Angewandte Chemie (International ed. in English). https://doi.org/10.1002/anie.201909313
  11. db:semantic_scholar B. Lehmann, P. Messerli, B. Keogh. (2019). "Journal of Alpine Research | Revue de géographie alpine, 95-4 | 2007".
  12. db:pubmed Cervantes J, Eber AE, Perper M et al.. (2018). "The role of zinc in the treatment of acne: A review of the literature.". Dermatologic therapy. https://doi.org/10.1111/dth.12576
  13. db:semantic_scholar Thamrong Lertudomphonwanit, M. Kelly, K. Bridwell et al.. (2017). "Rod fracture in adult spinal deformity surgery fused to the sacrum: prevalence, risk factors, and impact on health-related quality of life in 526 patients.". The spine journal. https://doi.org/10.1016/j.spinee.2018.02.008
  14. db:pubmed Singh M, Das RR. (2015). "WITHDRAWN: Zinc for the common cold.". The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.CD001364.pub5
  15. db:pubmed Gulani A, Sachdev HS. (2014). "Zinc supplements for preventing otitis media.". The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.CD006639.pub4
  16. db:pubmed Singh M, Das RR. (2013). "Zinc for the common cold.". The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.CD001364.pub4
  17. db:semantic_scholar D. Quah. (1993). "Galton's Fallacy and Tests of the Convergence Hypothesis (Now published in Scandinavian Journal of Economics 95 (4), 1993, pp.427-443.)". https://doi.org/10.2307/3440905
  18. db:crossref J.C. Longhurst. (1988). "Gastrointestinal reflexes". Gastroenterology. https://doi.org/10.1016/0016-5085(88)90514-8
Regulatory status of the substance
This substance is subject to regulatory requirements: hazardous waste management (BDO register). Details in the \"Regulatory Status (REACH/ECHA/CLP)\" section and on the SDS. Regulatory information — does not restrict purchase in this store.
🧪 Chemical Data
CAS Number
526-95-4
Molecular formula
C6H12O7
Molar mass
196.16 g/mol
IUPAC name (EN)
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
SMILES
C([C@H]([C@H]([C@@H]([C@H](C(=O)O)O)O)O)O)O
InChIKey
RGHNJXZEOKUKBD-SQOUGZDYSA-N
⚗️ Physicochemical properties
Density
1.24

Source: PubChem, NIST WebBook. Last updated: 2026-09-02

🔍 External identifiers
12 of 16 ID systems75%
DatabaseIdentifierActions
CAS Registry Number526-95-4Open →
PubChem CID10690[1]Open →
InChIKeyRGHNJXZEOKUKBD-SQOUGZDYSA-N[1]Open →
SMILESC([C@H]([C@H]([C@@H]([C@H](C(=O)O)O)O)O)O)O[1]
EC Number208-401-4[2]Open →
DrugBankDB13180Open →
KEGG CompoundC00257Open →
HMDBHMDB0000625Open →
ChemSpider10240[3]Open →
UNII (FDA)R4R8J0Q44BOpen →
NSC Number (NCI)77381Open →
WikiData QIDQ407569Open →

Sources: PubChem (NIH), Wikidata SPARQL, KEGG, ChEMBL (EBI), CompTox CTX (EPA).

📚 Scientific references (Chicago Author-Date) (3 sources)
  1. PubChem. National Center for Biotechnology Information (NIH/NLM), chemical compound database. dotyczy: PubChem CID · InChIKey · SMILES
  2. ECHA. EC Inventory — EINECS, ELINCS, NLP and List Numbers assigned under REACH. Helsinki: European Chemicals Agency. dotyczy: EC Number
  3. ChemSpider. Royal Society of Chemistry, chemical structure database. dotyczy: ChemSpider

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D-Gluconic acid solution — CAS 526-95-4, purity 49-53 wt. %(溶剂:H2O), 500ml. Listed by Beijing Tong Guang. Prepared from the supplier’s public catalogue; not verified against their internal data.

Data from PubChemSource: PubChem (NIH)