L-Valine (CAS 72-18-4)

L-Valine

CAS 72-18-4  ·  C5H11NO2  ·  MW 117.15 g/mol

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3D模型L-Valine,CAS 72-18-4,分子式C5H11NO2, 摩尔质量 117.15 g/mol
关于 L-Valine (CAS 72-18-4)

L-Valine (CAS 72-18-4) 是一种化学品,登记号为 CAS 72-18-4,分子式为 C5H11NO2,摩尔质量为 117.15 g/mol。

该分子包含 19 个原子,通过 18 个化学键连接。 该化合物的完整系统 IUPAC 名称为 (2S)-2-amino-3-methylbutanoic acid。 上方的交互式 3D 模型可查看原子的空间排列——您可以用鼠标旋转、用滚轮缩放,并在骨架 / 球棍 (Ball & Stick) / 空间填充 (Space Fill) 显示模式之间切换。

在理化性质方面, 分配系数 logP = -2.3 (负值,亲水性化合物),极性表面积 PSA = 63.3 Ų2 个氢键供体和 3 个氢键受体。 这些参数对于评估生物利用度以及与生物分子的相互作用至关重要。

该化合物的化学数据来自 PubChem(NIH NLM NCBI),全球最大的化学数据库之一。所有信息均自动更新,并附有符合 CLP 法规(EC 1272/2008)的 GHS 危险说明翻译。上方的小部件可用于教育、研究和商业用途。

理化性质
Wzór sumarycznyC5H11NO2
Masa molowa117.15 g/mol
IUPAC(2S)-2-amino-3-methylbutanoic acid
SMILESCC(C)[C@@H](C(=O)O)N
InChIKeyKZSNJWFQEVHDMF-BYPYZUCNSA-N
logP (XLogP3)-2.3
PSA63.3 Ų
HBD / HBA2 / 3
PubChem CIDCID 6287 ↗
科学文献

Related literature

20 artykułów · 14 open access · Źródła: PubMed, OpenAlex, Semantic Scholar

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📈 Timeline publikacji (20 artykułów)

1996: 1 artykułów19962002: 1 artykułów2009: 2 artykułów2010: 1 artykułów2011: 1 artykułów2013: 1 artykułów20132022: 1 artykułów2023: 1 artykułów2024: 7 artykułów2025: 3 artykułów2026: 1 artykułów2026

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Fa Liu, Jung-Eun Park, Kyung S. Lee et al. (2009) · Tetrahedron
AI Summary
The application of 4 in the solid-phase synthesis of polo-like kinase 1 (Plk1) polo box domain (PBD)-binding peptides retain PBD binding efficacy similar to a parent pThr containing peptide should be a highly useful reagent for the preparation of signal transduction-directed peptides.
Cytowania: 26Influential: 1Open AccessDOI ↗PubMed ↗PDF ↗
P. Strickland, Zheng Qian, M. Friesen et al. (2002) · Mutation research
AI Summary
It is indicated that significant amounts of PhIP are bioavailable from ingestion of fried or char-broiled meats, and that urinary PhIP metabolites reflect recent (12-24h) ingestion, and significant interindividual differences in the amounts of urine PhIP metabolite excreted are observed following ingestion of similar amounts ofPhIP.
Cytowania: 45Influential: 1$ PaywallDOI ↗PubMed ↗
L. Juknaitė, Yutaro Sugamata, K. Tokiwa et al. (2013) · Journal of Medicinal Chemistry
AI Summary
In vivo and in vitro neuronal activities of both enantiomers of IKM-159 prepared by enantioselective asymmetric synthesis are reported, consistent with a pharmacological action as competitive antagonist of AMPA receptors.
Cytowania: 20Open AccessDOI ↗PubMed ↗PDF ↗
T. Kasim, Andrey G. Yavorsky, I. Mandel et al. (2026) · Journal of Clinical Practice
AI Summary
Perioperative intravenous infusion of a balanced amino acid solution safely reduces the incidence and severity of AKI and improves renal functional parameters after cardiac surgery with CPB, supporting its use as an early nephroprotective strategy.
Open AccessDOI ↗PDF ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

同义词
L-valine · valine · 72-18-4 · (S)-Valine · (2S)-2-amino-3-methylbutanoic acid · (S)-2-Amino-3-methylbutanoic acid · 2-Amino-3-methylbutyric acid · (S)-2-Amino-3-methylbutyric acid · valina · L-alpha-Amino-beta-methylbutyric acid · L-valin · Valinum · (S)-alpha-Amino-beta-methylbutyric acid · NSC-76038 · l-(+)-alpha-Aminoisovaleric acid
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