L-Valine (CAS 72-18-4)

L-Valine

CAS 72-18-4  ·  C5H11NO2  ·  MW 117.15 g/mol

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3D model L-Valine, CAS 72-18-4, molecular formula C5H11NO2, molar mass 117.15 g/mol
About L-Valine (CAS 72-18-4)

L-Valine (CAS 72-18-4) is a chemical compound registered under number CAS 72-18-4, with the molecular formula C5H11NO2, and a molar mass of 117.15 g/mol.

The molecule contains 19 atoms connected by 18 chemical bonds. The full systematic IUPAC name of this compound is (2S)-2-amino-3-methylbutanoic acid. The interactive 3D model above lets you view the spatial arrangement of the atoms — you can rotate it with the mouse, zoom with the scroll wheel, and switch between skeletal / Ball & Stick / Space Fill visualization modes.

In terms of physicochemical properties, the partition coefficient logP = -2.3 (negative value, a hydrophilic compound), polar surface area PSA = 63.3 Ų, 2 donors and 3 hydrogen bond acceptors. These parameters are key when assessing bioavailability and interaction with biomolecules.

Chemical data for this compound comes from PubChem (NIH NLM NCBI), one of the world's largest chemical databases. All information is updated automatically and enriched with GHS hazard statement translations compliant with the CLP Regulation (EC 1272/2008). The widget above may be used for educational, research and commercial purposes.

Physicochemical properties
Wzór sumarycznyC5H11NO2
Masa molowa117.15 g/mol
IUPAC(2S)-2-amino-3-methylbutanoic acid
SMILESCC(C)[C@@H](C(=O)O)N
InChIKeyKZSNJWFQEVHDMF-BYPYZUCNSA-N
logP (XLogP3)-2.3
PSA63.3 Ų
HBD / HBA2 / 3
PubChem CIDCID 6287 ↗
Scientific literature

Related literature

20 artykułów · 14 open access · Źródła: PubMed, OpenAlex, Semantic Scholar

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📈 Timeline publikacji (20 artykułów)

1996: 1 artykułów19962002: 1 artykułów2009: 2 artykułów2010: 1 artykułów2011: 1 artykułów2013: 1 artykułów20132022: 1 artykułów2023: 1 artykułów2024: 7 artykułów2025: 3 artykułów2026: 1 artykułów2026

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Fa Liu, Jung-Eun Park, Kyung S. Lee et al. (2009) · Tetrahedron
AI Summary
The application of 4 in the solid-phase synthesis of polo-like kinase 1 (Plk1) polo box domain (PBD)-binding peptides retain PBD binding efficacy similar to a parent pThr containing peptide should be a highly useful reagent for the preparation of signal transduction-directed peptides.
Cytowania: 26Influential: 1Open AccessDOI ↗PubMed ↗PDF ↗
P. Strickland, Zheng Qian, M. Friesen et al. (2002) · Mutation research
AI Summary
It is indicated that significant amounts of PhIP are bioavailable from ingestion of fried or char-broiled meats, and that urinary PhIP metabolites reflect recent (12-24h) ingestion, and significant interindividual differences in the amounts of urine PhIP metabolite excreted are observed following ingestion of similar amounts ofPhIP.
Cytowania: 45Influential: 1$ PaywallDOI ↗PubMed ↗
L. Juknaitė, Yutaro Sugamata, K. Tokiwa et al. (2013) · Journal of Medicinal Chemistry
AI Summary
In vivo and in vitro neuronal activities of both enantiomers of IKM-159 prepared by enantioselective asymmetric synthesis are reported, consistent with a pharmacological action as competitive antagonist of AMPA receptors.
Cytowania: 20Open AccessDOI ↗PubMed ↗PDF ↗
T. Kasim, Andrey G. Yavorsky, I. Mandel et al. (2026) · Journal of Clinical Practice
AI Summary
Perioperative intravenous infusion of a balanced amino acid solution safely reduces the incidence and severity of AKI and improves renal functional parameters after cardiac surgery with CPB, supporting its use as an early nephroprotective strategy.
Open AccessDOI ↗PDF ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

Synonyms
L-valine · valine · 72-18-4 · (S)-Valine · (2S)-2-amino-3-methylbutanoic acid · (S)-2-Amino-3-methylbutanoic acid · 2-Amino-3-methylbutyric acid · (S)-2-Amino-3-methylbutyric acid · valina · L-alpha-Amino-beta-methylbutyric acid · L-valin · Valinum · (S)-alpha-Amino-beta-methylbutyric acid · NSC-76038 · l-(+)-alpha-Aminoisovaleric acid
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