# Edetate Calcium Disodium Anhydrous **CAS:** 23411-34-9 **PubChem CID:** [6093170](https://pubchem.ncbi.nlm.nih.gov/compound/6093170) **Molecular formula:** C₁₀H₁₈CaN₂Na₂O₁₁ **Molar mass:** 374.27 g/mol **IUPAC:** calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate **SMILES:** `C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Ca+2]` **InChIKey:** `SHWNNYZBHZIQQV-UHFFFAOYSA-J` **InChI:** `InChI=1S/C10H16N2O8.Ca.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;/q;+2;2*+1/p-4` ## Physicochemical properties | Parameter | Value | |---|---| | PSA | 167 Ų | | Hydrogen bond donors | 0 | | Hydrogen bond acceptors | 10 | | Rotatable bonds | 7 | | Heavy atoms | 23 | ## 3D structure The molecule contains 35 atoms connected by 31 chemical bonds. Interactive 3D model available at: https://molgod.org/molecule/23411-34-9/ ## GHS classification **Signal word:** Warning **Pictograms:** GHS07 ### Precautionary statements (P) - **P261** — Avoid breathing dust/fume/gas/mist/vapours/spray ## Synonyms - Edetate calcium disodium - EDTA calcium disodium - Detoxamin - Calcium disodium ethylenediaminetetraacetate - Edetate calcium disodium anhydrous - INS NO.385 - INS-385 - Edetate Calcium Disodium (anhydrous) - NSC-310151 - C10H12CaN2Na2O8 ## Regulatory compliance checklist Status based on: ADR 2025 (Table A), REACH Annex XVII, CLP Annex VI (harmonised classification), hazard class from the m14-spill DB, SVHC, GIS and the Polish OEL list. Principle: no data = no claim (we do NOT declare "no restrictions" without a basis). 4 required / 12 items ### SDS (Safety Data Sheet) available - **required** (required / sds) - How to comply: Requirement: current SDS compliant with Reg. 1907/2006 (REACH) Annex II, 16-section format. - [Source / form](https://echa.europa.eu/information-on-chemicals) ### Compliant CLP label (pictograms + signal word + H/P) - **required** (required / clp_label) - How to comply: The label must include: GHS pictograms, the signal word (Danger/Warning), hazard (H) and precautionary (P) statements, and manufacturer details. Required since 2010 (substances) and 2015 (mixtures). - [Source / form](https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1272) ### Chemical OSH training (substance-specific) - **required** (required / bhp_training) - How to comply: Laboratory staff: initial training (general induction + job-specific) + refresher training every 5 years (or every 3 for engineering/technical positions). Documentation kept in personnel files. - [Source / form](https://isap.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20040180169) ### BDO registration (Polish Waste Database) - **not applicable** (not_applicable / bdo_registration) - How to comply: The verified GHS classification does not indicate classes resulting in hazardous waste — BDO registration for this substance is not required. Verify the EWC code for the specific waste form. - [Source / form](https://bdo.mos.gov.pl/) ### ADR transport (international agreement) - **to be verified** (unknown / adr_transport) - How to comply: No ADR data in the MOL-GOD dataset for this CAS number. Do NOT assume there are no restrictions — before shipping, verify the transport classification in ADR 2025 (Table A) and in section 14 of the safety data sheet (SDS). - [Source / form](https://unece.org/transport/dangerous-goods/adr-2025-files) ### REACH registration (>1 t/year EU import) - **conditional** (conditional / reach_registration) - How to comply: Importers/manufacturers ≥1 tonne/year must register the substance with ECHA (technical dossier + Chemical Safety Report if ≥10 t). Check the ECHA Annex VI / registered substances list. - [Source / form](https://echa.europa.eu/regulations/reach/registration) ### SVHC notification (Substances of Very High Concern) - **to be verified** (unknown / svhc_declaration) - How to comply: SVHC status not verified against the available dataset — check the current ECHA candidate list; do not assume the absence of an entry. - [Source / form](https://echa.europa.eu/candidate-list-table) ### REACH Annex XIV (authorisation list) - **to be verified** (unknown / reach_annex_xiv) - How to comply: Not verified against the ECHA Authorisation List — check REACH Annex XIV. - [Source / form](https://echa.europa.eu/authorisation-list) ### REACH Annex XVII (use/marketing restrictions) - **to be verified** (unknown / reach_annex_xvii) - How to comply: No entry in the harmonised classification dataset (CLP Annex VI) for this CAS number — status of entries 28–30 (CMR ban) NOT VERIFIED; do not assume the restriction does not apply. The dataset of Annex XVII restrictions is also incomplete — check the consolidated Annex XVII and the harmonised CMR classification on the ECHA website. - [Source / form](https://echa.europa.eu/substances-restricted-under-reach) ### OEL — Occupational Exposure Limit in the working environment - **to be verified** (unknown / nds_workplace) - How to comply: No NDS data in the MOL-GOD dataset (incomplete set — ~41 of ~600 substances in the list). Absence does NOT mean there is no NDS — check the full list in Dz.U. 2024 poz. 1017 (Regulation of the Ministry of Family and Social Policy of 4 September 2024), and where none exists apply the OEL from EU directives or values recommended by NIOSH/ACGIH. - [Source / form](https://isap.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20240001017) ### GIS register (precursors / psychotropics) - **to be verified** (unknown / gis_register) - How to comply: Does not appear in the available working set of precursors (list incomplete). Absence is NOT a confirmation — verify against Annex I of Reg. (EC) 273/2004 and the GIS list before placing on the market. - [Source / form](https://www.gov.pl/web/gis) ### Safety Data Sheet in Polish - **required** (required / sds_pl) - How to comply: Requirement: SDS in Polish for trade in PL (Art. 31 REACH + Chemical Substances Act Art. 17). - [Source / form](https://isap.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20012112135) ## Data sources - [PubChem CID 6093170](https://pubchem.ncbi.nlm.nih.gov/compound/6093170) - [NIST WebBook](https://webbook.nist.gov/cgi/cbook.cgi?ID=23411-34-9) - [ChEMBL](https://www.ebi.ac.uk/chembl/g/#search_results/all/query=23411-34-9) --- - Canonical: https://molgod.org/molecule/23411-34-9/ **Licence:** Chemical facts in this record come from the public sources credited above; MolGod.org claims no rights in them. The selection, arrangement and texts of this record are © MolGod.org, all rights reserved. Details: https://molgod.org/copyright/#data **How to cite:** MolGod.org. "Edetate Calcium Disodium Anhydrous (CAS 23411-34-9)." Last modified 2026-09-03. https://molgod.org/molecule/23411-34-9/ — for a chemical fact, cite its primary source (PubChem CID 6093170); for a 3D model file, cite its MolGod ID, the variant and the SHA-256 from its licence record. *Last updated: 2026-09-03 · Generator: MOL-GOD v3.12.33*