# Poly(N-isopropylacrylamide-co-methacrylic acid)

**CAS:** 151954-97-1  
**PubChem CID:** [3081324](https://pubchem.ncbi.nlm.nih.gov/compound/3081324)  
**Molecular formula:** C₁₀H₁₇NO₃  
**Molar mass:** 199.25 g/mol  
**IUPAC:** 2-methylprop-2-enoic acid;N-propan-2-ylprop-2-enamide  
**SMILES:** `CC(C)NC(=O)C=C.CC(=C)C(=O)O`  
**InChIKey:** `BGJOTKHBFYMJST-UHFFFAOYSA-N`  
**InChI:** `InChI=1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)`  

## Physicochemical properties

| Parameter | Value |
|---|---|
| PSA | 66.4 Ų |
| Hydrogen bond donors | 2 |
| Hydrogen bond acceptors | 3 |
| Rotatable bonds | 3 |
| Heavy atoms | 14 |

## 3D structure

The molecule contains 31 atoms connected by 29 chemical bonds. Interactive 3D model available at: https://molgod.org/molecule/151954-97-1/

## Synonyms

- 151954-97-1
- N-(isopropylacrylamide)methacrylic acid copolymer
- DTXCID4087408
- NIPAM-MAA copolymer
- P(NIPAM-co-MAA)
- RefChem:175099
- 2-methylprop-2-enoic acid;N-propan-2-ylprop-2-enamide
- SCHEMBL2527192
- Poly(N-isopropylacrylamide-r-methacrylic acid) random polymer
- 2-Methylprop-2-enoic acid--N-(propan-2-yl)prop-2-enamide (1/1)

## Data sources

- [PubChem CID 3081324](https://pubchem.ncbi.nlm.nih.gov/compound/3081324)
- [Wikidata](https://www.wikidata.org/wiki/Q83034007)
- [NIST WebBook](https://webbook.nist.gov/cgi/cbook.cgi?ID=151954-97-1)
- [ChEMBL](https://www.ebi.ac.uk/chembl/g/#search_results/all/query=151954-97-1)

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*Last updated: 2026-10-17 · Generator: MOL-GOD v3.12.33*